{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T20:01:00Z","timestamp":1791403260176,"version":"4.3.3"},"reference-count":26,"publisher":"Georg Thieme Verlag KG","issue":"01","license":[{"start":{"date-parts":[[2026,1,25]],"date-time":"2026-01-25T00:00:00Z","timestamp":1769299200000},"content-version":"vor","delay-in-days":24,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Arq Neuropsiquiatr"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Tarsila do Amaral's painting \u201cAbaporu\u201d is a seminal work in Brazilian modernist art, yet its interpretation continues to intrigue scholars due to its complex symbolism.<\/jats:p>\n                  <jats:p>To examine \u201cAbaporu\u201d through the perspective of neuroesthetics, exploring potential parallels between its visual elements and sensory disturbances characteristics of migraine aura.<\/jats:p>\n                  <jats:p>A structured review of primary and secondary art-historical sources and a systematic literature search in PubMed and Google Scholar were conducted. The analysis focused on Amaral's recurrent use of disproportion and gigantism in the 1920s and on evaluating the plausibility of a neuroesthetic hypothesis in this art-historical context.<\/jats:p>\n                  <jats:p>Our analysis indicated that the gigantism and deliberate deformation in \u201cAbaporu\u201d belong to a consistent program already evident in Amaral's 1920s painting. From this perspective, the painting's oversized feet and hands contrasting with a diminutive head evoke perceptual alterations reminiscent of macropsia and micropsia, phenomena linked to Alice in Wonderland Syndrome and migraine aura. Its vibrant palette and melancholic undertones, likewise, resound the sensory disturbances and affective dimensions associated with migraine, suggesting that Amaral's programmatic distortions also invite a neuroesthetic reading.<\/jats:p>\n                  <jats:p>While no evidence supports a medical diagnosis of migraine in Amaral, the visual motifs and techniques in \u201cAbaporu\u201d can be read both as deliberate esthetic strategies of her Pau-Brasil and Anthropophagic phases and as intuitively resonant with neurological models of altered perception. This dual lens enriches our understanding of art's capacity to embody complex perceptual experiences and encourages further interdisciplinary dialogue between art history and neuroscience.<\/jats:p>","DOI":"10.1055\/s-0045-1814376","type":"journal-article","created":{"date-parts":[[2026,1,25]],"date-time":"2026-01-25T23:30:22Z","timestamp":1769383822000},"page":"001-006","source":"Crossref","is-referenced-by-count":1,"title":["A neurological perspective on Tarsila do Amaral's \u201cAbaporu\u201d: migraine aura inspiring art?"],"prefix":"10.1055","volume":"84","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3122-9484","authenticated-orcid":false,"given":"Wallyson Pablo de Oliveira","family":"Souza","sequence":"additional","affiliation":[{"name":"Universidade Federal do Delta do Parna\u00edba, Parna\u00edba PI, Brazil."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7729-7303","authenticated-orcid":false,"given":"Patrick Emanuell Mesquita","family":"Sousa-Santos","sequence":"additional","affiliation":[{"name":"Universidade Estadual Paulista \u201cJ\u00falio de Mesquita Filho\u201d, Faculdade de Medicina de Botucatu, Botucatu SP, Brazil."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2383-289X","authenticated-orcid":false,"given":"Juliane Prieto Peres","family":"Mercante","sequence":"additional","affiliation":[{"name":"Universidade de S\u00e3o Paulo, Faculdade de Medicina, Hospital das Cl\u00ednicas, S\u00e3o Paulo SP, Brazil."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0068-1905","authenticated-orcid":false,"given":"Mario Fernando Prieto","family":"Peres","sequence":"additional","affiliation":[{"name":"Universidade de S\u00e3o Paulo, Faculdade de Medicina, Hospital das Cl\u00ednicas, S\u00e3o Paulo SP, Brazil."},{"name":"Universidade de S\u00e3o Paulo, Instituto de Psiquiatria, S\u00e3o Paulo SP, Brazil."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2343-9679","authenticated-orcid":false,"given":"Raimundo Pereira","family":"Silva-N\u00e9to","sequence":"additional","affiliation":[{"name":"Universidade Federal do Delta do Parna\u00edba, Parna\u00edba PI, Brazil."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2026,1,25]]},"reference":[{"key":"ref1","volume-title":"A arte moderna de Tarsila do Amaral: um olhar sobre duas de suas principais obras: Abaporu e Oper\u00e1rios","author":"E CS Sousa","year":"2013"},{"issue":"02","key":"ref2","doi-asserted-by":"publisher","first-page":"254","DOI":"10.1080\/13260219.2014.939139","article-title":"Corpos pulsantes: \u2018A Carioca\u2019 de Pedro Am\u00e9rico e \u2018A Negra\u2019 e \u2018Abaporu\u2019 de Tarsila do Amaral","volume":"20","author":"Cd Oliveira","year":"2014","journal-title":"J Iber Lat Am Res."},{"issue":"01","key":"ref3","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1177\/0333102417738202","article-title":"Headache Classification Committee of the International Headache Society (IHS) The International Classification of Headache Disorders, 3rd edition","volume":"38","year":"2018","journal-title":"Cephalalgia"},{"issue":"10","key":"ref4","doi-asserted-by":"publisher","first-page":"979","DOI":"10.1177\/0333102416657147","article-title":"Clinical features of migraine aura: Results from a prospective diary-aided study","volume":"37","author":"M Viana","year":"2017","journal-title":"Cephalalgia"},{"key":"ref5","doi-asserted-by":"publisher","first-page":"1009","DOI":"10.1212\/CON.0000000000000627","article-title":"The migraine aura","volume":"24","author":"A Charles","year":"2018","journal-title":"Continuum (Minneap Minn)"},{"issue":"01","key":"ref6","doi-asserted-by":"publisher","first-page":"10","DOI":"10.48208\/HeadacheMed.2020.4","article-title":"Migraine aura: results from an art contest","volume":"11","author":"BdF Dias","year":"2020","journal-title":"Headache Med"},{"issue":"06","key":"ref7","doi-asserted-by":"publisher","first-page":"17","DOI":"10.1007\/s11910-020-01037-3","article-title":"Migraine Aura: Updates in pathophysiology and management","volume":"20","author":"J Lai","year":"2020","journal-title":"Curr Neurol Neurosci Rep"},{"issue":"06","key":"ref8","doi-asserted-by":"publisher","first-page":"739","DOI":"10.1055\/s-0039-1700525","article-title":"Migraine aura: pathophysiology, mimics, and treatment options","volume":"39","author":"C L Fraser","year":"2019","journal-title":"Semin Neurol"},{"issue":"03","key":"ref9","doi-asserted-by":"publisher","first-page":"259","DOI":"10.1212\/CPJ.0000000000000251","article-title":"Alice in Wonderland syndrome: A systematic review","volume":"6","author":"J D Blom","year":"2016","journal-title":"Neurol Clin Pract"},{"key":"ref10","doi-asserted-by":"publisher","first-page":"5","DOI":"10.1016\/j.pediatrneurol.2017.08.008","article-title":"Alice in Wonderland syndrome: A historical and medical review","volume":"77","author":"O Farooq","year":"2017","journal-title":"Pediatr Neurol"},{"issue":"09","key":"ref11","doi-asserted-by":"publisher","first-page":"1233","DOI":"10.1111\/head.12688","article-title":"Alice in Wonderland syndrome, burning mouth syndrome, cold stimulus headache, and HaNDL: Narrative review","volume":"55","author":"M M Valen\u00e7a","year":"2015","journal-title":"Headache"},{"issue":"04","key":"ref12","doi-asserted-by":"publisher","first-page":"134","DOI":"10.48208\/HeadacheMed.2017.21","article-title":"\u201cA slow-motion world\u201d as a manifestation of Alice in Wonderland syndrome: a case report","volume":"8","author":"L CA Almeida","year":"2017","journal-title":"Headache Med"},{"issue":"04","key":"ref13","doi-asserted-by":"publisher","first-page":"389","DOI":"10.3934\/Neuroscience.2020024","article-title":"Alice in Wonderland syndrome (AIWS): a research overview","volume":"7","author":"M M Hossain","year":"2020","journal-title":"AIMS Neurosci"},{"issue":"08","key":"ref14","doi-asserted-by":"publisher","first-page":"5146","DOI":"10.1007\/s00415-024-12471-5","article-title":"Alice in Wonderland Syndrome (AIWS): prevalence and characteristics in adults with migraine","volume":"271","author":"M P Fitzek","year":"2024","journal-title":"J Neurol"},{"issue":"6664","key":"ref15","doi-asserted-by":"publisher","first-page":"1670","DOI":"10.1136\/bmj.297.6664.1670","article-title":"Migraine aura as artistic inspiration","volume":"297","author":"G N Fuller","year":"1988","journal-title":"BMJ"},{"issue":"10","key":"ref16","doi-asserted-by":"publisher","first-page":"525","DOI":"10.1177\/014107680209501024","article-title":"Inspired by migraine","volume":"95","author":"E H Jellinek","year":"2002","journal-title":"J R Soc Med"},{"issue":"08","key":"ref17","doi-asserted-by":"publisher","first-page":"417","DOI":"10.1258\/jrsm.95.8.417","article-title":"Inspired by migraine: Sarah Raphael's \u2018Strip!\u2019 paintings","volume":"95","author":"K Podoll","year":"2002","journal-title":"J R Soc Med"},{"issue":"08","key":"ref18","doi-asserted-by":"publisher","first-page":"686","DOI":"10.1111\/j.1468-2982.2000.00113.x","article-title":"Migraine aura, illusory vertical splitting, and Picasso","volume":"20","author":"M D Ferrari","year":"2000","journal-title":"Cephalalgia"},{"issue":"01","key":"ref19","first-page":"e2722","article-title":"Tarsila do Amaral: uma escolha pela arte","volume":"1","author":"M E Bonow","year":"2007","journal-title":"Travessias"},{"issue":"11","key":"ref20","first-page":"1","article-title":"Devouring surrealism: Tarsila do Amaral's Abaporu","author":"M Greet","year":"2015","journal-title":"Papers of Surrealism"},{"key":"ref21","volume-title":"Tarsila: Cat\u00e1logo Raisonn\u00e9 Tarsila do Amaral","author":"M E Saturni","year":"2008"},{"key":"ref22","volume-title":"Tarsila do Amaral: Inventing Modern Art in Brazil","author":"S D'Alessandro","year":"2017"},{"issue":"08","key":"ref24","doi-asserted-by":"publisher","first-page":"977","DOI":"10.1111\/head.14380","article-title":"Physical activity pattern and migraine according to aura symptoms in the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil) cohort: A cross-sectional study","volume":"62","author":"A B Oliveira","year":"2022","journal-title":"Headache"},{"issue":"01","key":"ref25","doi-asserted-by":"publisher","first-page":"37","DOI":"10.1186\/s10194-017-0742-1","article-title":"Anxiety and depression symptoms and migraine: a symptom-based approach research","volume":"18","author":"M FP Peres","year":"2017","journal-title":"J Headache Pain"},{"issue":"07","key":"ref26","doi-asserted-by":"publisher","first-page":"741","DOI":"10.1136\/jnnp-2015-312233","article-title":"Migraine and its psychiatric comorbidities","volume":"87","author":"M T Minen","year":"2016","journal-title":"J Neurol Neurosurg Psychiatry"},{"issue":"08","key":"ref27","doi-asserted-by":"publisher","first-page":"1960","DOI":"10.1007\/s00415-012-6725-x","article-title":"Psychiatric comorbidities of episodic and chronic migraine","volume":"260","author":"D C Buse","year":"2013","journal-title":"J Neurol"}],"container-title":["Arquivos de Neuro-Psiquiatria"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/s-0045-1814376.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,25]],"date-time":"2026-01-25T23:30:25Z","timestamp":1769383825000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/s-0045-1814376"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1]]},"references-count":26,"journal-issue":{"issue":"01","published-online":{"date-parts":[[2026,1,25]]},"published-print":{"date-parts":[[2026,1]]}},"alternative-id":["s00451814376"],"URL":"https:\/\/doi.org\/10.1055\/s-0045-1814376","archive":["Portico","CLOCKSS"],"relation":{},"ISSN":["0004-282X","1678-4227"],"issn-type":[{"value":"0004-282X","type":"print"},{"value":"1678-4227","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,1]]}}}