{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T23:10:46Z","timestamp":1790723446095,"version":"4.1.0"},"reference-count":40,"publisher":"Georg Thieme Verlag KG","issue":"04","license":[{"start":{"date-parts":[[2026,1,22]],"date-time":"2026-01-22T00:00:00Z","timestamp":1769040000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Eur J Dent"],"published-print":{"date-parts":[[2026,10]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>The moisture-tolerant resin-based sealant Embrace WetBond (EWB), designed for effective bonding in moist conditions, offers a promising solution for caries prevention in challenging clinical environments. This study aimed to evaluate and compare its retention rate and caries-preventive efficacy in newly erupted permanent molars under two distinct clinical settings.<\/jats:p>\n                  <jats:p>This split-mouth randomized controlled trial assessed EWB sealant under moisture-controlled and non-moisture-controlled conditions in schoolchildren aged 6 to 14 years with bilateral, non-cavitated molars. A total of 37 participants (112 teeth; 56 per group) were randomized, each serving as their own control. Sealant retention, caries prevention, marginal discoloration, marginal adaptation, color match, and smoothness of surface were assessed at 1, 6, and 12 months using modified USPHS criteria. Statistical analysis included the chi-square test, Mann-Whitney U test, and Friedman test to compare retention rates and sealant performance over time.<\/jats:p>\n                  <jats:p>A total of 37 children (56 teeth per group) were included, with balanced baseline characteristics due to the split-mouth design. At 12 months, sealant retention significantly declined in both groups (Group I: 96.4% at 1 month to 49% at 12 months; Group II: 96.4 to 54.9%; p\u2009&lt;\u20090.001), though no significant differences were observed between groups (p\u2009&gt;\u20090.05). Caries incidence was minimal, with only 2% of teeth affected at 12 months in each group. Apart from retention, no other parameters showed significant deterioration over 12 months.<\/jats:p>\n                  <jats:p>Pit and fissure sealants demonstrated similar effectiveness in preventing occlusal caries under both moisture-controlled and non-moisture-controlled conditions over 12 months. Their comparable performance in limited moisture-controlled settings highlights their suitability for real-world clinical practice and public health programs.<\/jats:p>","DOI":"10.1055\/s-0045-1814727","type":"journal-article","created":{"date-parts":[[2026,1,23]],"date-time":"2026-01-23T00:18:34Z","timestamp":1769127514000},"page":"1152-1161","source":"Crossref","is-referenced-by-count":0,"title":["Evaluation of Clinical Performance of Moisture-tolerant Sealant on Pit and Fissure Caries in Two Different Setting Conditions: A Randomized Controlled Trial"],"prefix":"10.1055","volume":"20","author":[{"ORCID":"https:\/\/orcid.org\/0009-0001-6359-1069","authenticated-orcid":false,"given":"Shweta","family":"Dangi","sequence":"additional","affiliation":[{"name":"Nims Dental College and Hospital, Nims University Rajasthan, Jaipur, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0547-7628","authenticated-orcid":false,"given":"Kumar Gaurav","family":"Chhabra","sequence":"additional","affiliation":[{"name":"Nims Dental College and Hospital, Nims University Rajasthan, Jaipur, India"},{"name":"Research and Development Cell, Datta Meghe Institute of Higher Education and Research, Wardha, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8442-2280","authenticated-orcid":false,"given":"Naganandini","family":"S.","sequence":"additional","affiliation":[{"name":"Nims Dental College and Hospital, Nims University Rajasthan, Jaipur, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4709-5054","authenticated-orcid":false,"given":"Pankaj","family":"Chaudhary","sequence":"additional","affiliation":[{"name":"Nims Dental College and Hospital, Nims University Rajasthan, Jaipur, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-6057-3327","authenticated-orcid":false,"given":"Seemadevi","family":"T.","sequence":"additional","affiliation":[{"name":"Nims Dental College and Hospital, Nims University Rajasthan, Jaipur, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-9608-009X","authenticated-orcid":false,"given":"Harshit","family":"Srivastava","sequence":"additional","affiliation":[{"name":"Nims Dental College and Hospital, Nims University Rajasthan, Jaipur, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2026,1,22]]},"reference":[{"issue":"9555","key":"ref1","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/S0140-6736(07)60031-2","article-title":"Dental caries","volume":"369","author":"R H 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Singh","year":"2022","journal-title":"J Pharm Negat Results"},{"issue":"04","key":"ref41","first-page":"306","article-title":"A one-year evaluation of a free fissure sealant program","volume":"3","year":"2016","journal-title":"J Dent Biomater"}],"container-title":["European Journal of 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