{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T20:39:31Z","timestamp":1777927171709,"version":"3.51.4"},"reference-count":15,"publisher":"Georg Thieme Verlag KG","issue":"01","license":[{"start":{"date-parts":[[2026,1,5]],"date-time":"2026-01-05T00:00:00Z","timestamp":1767571200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["World J Nucl Med"],"published-print":{"date-parts":[[2026,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Pheochromocytomas and paragangliomas are relatively rare tumors, with an incidence of approximately 0.6 cases per 100,000 person-years. Moreover, the co-occurrence of these tumors is extremely rare and is often associated with pheochromocytomas\/paragangliomas-related pathogenic mutations. We present the case of a 33-year-old female diagnosed with bilateral carotid body paragangliomas and a concurrently detected pheochromocytoma, with metastases to the abdominal lymph nodes and lung. DNA analysis revealed a mutation in the succinate dehydrogenase subunit D gene. The tumors displayed high-grade SSTR expression (Krenning grade 4 uptake) on Gallium-68 [\u2076\u2078Ga]-DOTA-(Tyr3)-octreotate Positron Emission Tomography\/Computed Tomography, with no significant tracer concentration on the I-131 MIBG scan. Another notable feature in this case was the visually evident intra- and inter-tumoral metabolic heterogeneity on 18F-fluorodeoxyglucose positron emission tomography\/computed tomography, especially within the multiple carotid paragangliomas. With the adoption of a multimodality diagnostic approach (MRI, FDG PET\/CT, SSTR PET\/CT, and I-131 MIBG scintigraphy), a holistic theranostic approach was employed with the most rational therapeutic option offered to the patient.<\/jats:p>","DOI":"10.1055\/s-0045-1814731","type":"journal-article","created":{"date-parts":[[2026,1,5]],"date-time":"2026-01-05T23:53:55Z","timestamp":1767657235000},"page":"087-092","source":"Crossref","is-referenced-by-count":0,"title":["Synchronous Bilateral Shamblin Type III Carotid Body Tumors and Adrenal Pheochromocytoma with SDHD Mutation: A Rare Presentation, with Multimodality Imaging Findings"],"prefix":"10.1055","volume":"25","author":[{"given":"Roopal","family":"Agrawal","sequence":"additional","affiliation":[{"name":"Radiation Medicine Centre, Bhabha Atomic Research Centre, Tata Memorial Centre Annexe, Parel, Mumbai, Maharashtra, India"},{"name":"Homi Bhabha National Institute, Mumbai, Maharashtra, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Keerti","family":"Sitani","sequence":"additional","affiliation":[{"name":"Radiation Medicine Centre, Bhabha Atomic Research Centre, Tata Memorial Centre Annexe, Parel, Mumbai, Maharashtra, India"},{"name":"Homi Bhabha National Institute, Mumbai, Maharashtra, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6607-2558","authenticated-orcid":false,"given":"Sandip","family":"Basu","sequence":"additional","affiliation":[{"name":"Radiation Medicine Centre, Bhabha Atomic Research Centre, Tata Memorial Centre Annexe, Parel, Mumbai, Maharashtra, India"},{"name":"Homi Bhabha National Institute, Mumbai, Maharashtra, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2026,1,5]]},"reference":[{"issue":"06","key":"ref1","doi-asserted-by":"crossref","first-page":"552","DOI":"10.1056\/NEJMra1806651","article-title":"Pheochromocytoma and paraganglioma","volume":"381","author":"H PH Neumann","year":"2019","journal-title":"N Engl J Med"},{"key":"ref2","doi-asserted-by":"crossref","first-page":"824076","DOI":"10.3389\/fsurg.2022.824076","article-title":"Composite paraganglioma of the celiac trunk: a case report and a comprehensive review of the literature","volume":"9","author":"G Tzikos","year":"2022","journal-title":"Front Surg"},{"issue":"03","key":"ref3","first-page":"271","article-title":"Pheochromocytoma and paraganglioma: from clinical findings to diagnosis","volume":"54","author":"N Aygun","year":"2020","journal-title":"Sisli Etfal Hastan Tip Bul"},{"issue":"10","key":"ref4","first-page":"1613","article-title":"Comparison of 6 different 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Robertson","year":"2019","journal-title":"Eur J Vasc Endovasc Surg"},{"issue":"01","key":"ref14","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1097\/MNM.0000000000000209","article-title":"The current place and indications of 131I-metaiodobenzylguanidine therapy in the era of peptide receptor radionuclide therapy: determinants to consider for evolving the best practice and envisioning a personalized approach","volume":"36","author":"S Basu","year":"2015","journal-title":"Nucl Med Commun"},{"issue":"06","key":"ref15","doi-asserted-by":"crossref","first-page":"1029","DOI":"10.3390\/cancers17061029","article-title":"Pheochromocytomas and paragangliomas\u2014current management","volume":"17","author":"A Brewczy\u0144ski","year":"2025","journal-title":"Cancers (Basel)"}],"container-title":["World Journal of Nuclear 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