{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,18]],"date-time":"2026-05-18T23:11:32Z","timestamp":1779145892633,"version":"3.51.4"},"reference-count":24,"publisher":"Georg Thieme Verlag KG","issue":"02","license":[{"start":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T00:00:00Z","timestamp":1772150400000},"content-version":"vor","delay-in-days":26,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Arq Neuropsiquiatr"],"published-print":{"date-parts":[[2026,2]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Palliative care has been shown to yield benefits in terms of quality of life and therapeutic planning in oncological and non-oncological diseases, but its integration in neurology remains limited.<\/jats:p>\n                  <jats:p>To evaluate the predictive factors of mortality in neurological patients to improve prognosis.<\/jats:p>\n                  <jats:p>In this 1-year cohort study, we followed patients aged\u2009&gt;\u200918 years hospitalized in a neurological Semi-Intensive Care Unit in Brazil. The patients were categorized into two groups based on palliative care indication: those with and those without indication. The palliative care criteria included a \u201cno\u201d response to the Surprise Question, a Palliative Performance Scale (PPS) score below 70%, or significant weight loss (&gt; 5%) with associated body changes.<\/jats:p>\n                  <jats:p>We included 166 patients, 87 with indication and 79 without it. The group with indication had a 29.8% mortality rate (26 deaths) and a 27.7-fold higher risk of death. The factors associated with increased mortality risk within 1 year included PPS score\u2009&lt;\u200940%, answering \u201cno\u201d to the Surprise Question, and weight loss. Notably, 62% (n\u2009=\u200954) of the group with indication were admitted to the Intensive Care Unit (ICU), compared to 12% (n\u2009=\u200912) in the group without indication. Advanced directives were only documented in 31% (n\u2009=\u200927) of the group with indication and in 59% (n\u2009=\u200916) of the patients who died. Prognostic assessment in neurological diseases is challenging due to limited data.<\/jats:p>\n                  <jats:p>In the present study, we found that the PPS score, the Surprise Question, and weight loss were significant predictors of mortality within 1 year. These findings highlight the need for further research to provide better end-of-life markers and ensure greater autonomy in neurological disease management.<\/jats:p>","DOI":"10.1055\/s-0046-1816036","type":"journal-article","created":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T23:30:41Z","timestamp":1772235041000},"page":"001-008","source":"Crossref","is-referenced-by-count":0,"title":["Analysis of mortality predictors in a 1-year cohort of neuropalliative care patients"],"prefix":"10.1055","volume":"84","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8782-5982","authenticated-orcid":false,"given":"Diego Belandrino","family":"Swerts","sequence":"additional","affiliation":[{"name":"Hospital Israelita Albert Einstein, Faculdade Israelita de Ci\u00eancias da Sa\u00fade Albert Einstein, S\u00e3o Paulo SP, Brazil."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7200-2289","authenticated-orcid":false,"given":"Polyana Vulcano de Toledo","family":"Piza","sequence":"additional","affiliation":[{"name":"Hospital Israelita Albert Einstein, S\u00e3o Paulo SP, Brazil."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4210-1489","authenticated-orcid":false,"given":"Ana Lu\u00edza","family":"Ara\u00fajo","sequence":"additional","affiliation":[{"name":"Hospital Israelita Albert Einstein, S\u00e3o Paulo SP, Brazil."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1146-8146","authenticated-orcid":false,"given":"Bernard Lobato","family":"Prado","sequence":"additional","affiliation":[{"name":"Hospital Israelita Albert Einstein, S\u00e3o Paulo SP, Brazil."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-7204-9439","authenticated-orcid":false,"given":"Rafael Ferreira","family":"Docema","sequence":"additional","affiliation":[{"name":"Hospital Israelita Albert Einstein, Faculdade Israelita de Ci\u00eancias da Sa\u00fade Albert Einstein, S\u00e3o Paulo SP, Brazil."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-4499-0707","authenticated-orcid":false,"given":"Caroline","family":"Miyake","sequence":"additional","affiliation":[{"name":"Hospital Israelita Albert Einstein, Faculdade Israelita de Ci\u00eancias da Sa\u00fade Albert Einstein, S\u00e3o Paulo SP, Brazil."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-4364-357X","authenticated-orcid":false,"given":"Hye Sol","family":"Hwang","sequence":"additional","affiliation":[{"name":"Hospital Israelita Albert Einstein, Faculdade Israelita de Ci\u00eancias da Sa\u00fade Albert Einstein, S\u00e3o Paulo SP, Brazil."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0068-1905","authenticated-orcid":false,"given":"Mario Fernando Prieto","family":"Peres","sequence":"additional","affiliation":[{"name":"Hospital Israelita Albert Einstein, S\u00e3o Paulo SP, Brazil."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2026,2,27]]},"reference":[{"issue":"05","key":"ref1","doi-asserted-by":"publisher","first-page":"569","DOI":"10.1055\/s-0038-1668074","article-title":"Neuropalliative Care: A Practical Guide for the Neurologist","volume":"38","author":"K Brizzi","year":"2018","journal-title":"Semin Neurol"},{"issue":"08","key":"ref2","doi-asserted-by":"publisher","first-page":"764","DOI":"10.1212\/WNL.0b013e318282509c","article-title":"Estimating and communicating prognosis in advanced neurologic disease","volume":"80","author":"R G Holloway","year":"2013","journal-title":"Neurology"},{"issue":"02","key":"ref3","doi-asserted-by":"publisher","first-page":"130","DOI":"10.3109\/15360288.2014.911801","article-title":"Strengthening of palliative care as a component of 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