{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T06:49:38Z","timestamp":1777877378965,"version":"3.51.4"},"reference-count":31,"publisher":"Georg Thieme Verlag KG","issue":"02","license":[{"start":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T00:00:00Z","timestamp":1777507200000},"content-version":"vor","delay-in-days":29,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Int Arch Otorhinolaryngol"],"published-print":{"date-parts":[[2026,4]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Cancer patients undergoing potentially-ototoxic chemotherapy may present a series of hearing disorders and risk factors prior to treatment. Thus, it is necessary to know the profile of these patients to promote preventive actions and guidelines regarding the hearing health of these individuals.<\/jats:p>\n                  <jats:p>To describe and relate the hearing characteristics of patients entering a chemotherapy service before the exposure to potentially-ototoxic drugs.<\/jats:p>\n                  <jats:p>We conducted a cross-sectional study of 261 individuals who started chemotherapy between April and December 2022. All patients filled out a hearing case history and underwent otoscopy. Individuals who had a non-altered otoscopy due to obstructive cerumen underwent distortion-product otoacoustic emissions (DPOAEs) at 2, 4, 6, 8, 10, and 12\u2009kHz in both ears.<\/jats:p>\n                  <jats:p>In total, 83% of the patients reported good hearing and 31% described some level of hearing impairment. The most prevalent self-reported hearing issue was tinnitus (35%). Only 12% had a medical diagnosis of hearing loss, and 20% had obstructive cerumen during otoscopy. Individuals who reported hearing impairments such as reduced hearing and difficulty understanding noises demonstrated fewer responses in the DPOAEs at various frequencies. In addition, there were significant differences in DPOAE amplitudes among different age groups. Given the substantial burden of hearing loss with ageing, attention to this population is essential for the possibility of preventing or delaying hearing loss.<\/jats:p>\n                  <jats:p>Cancer patients entering a chemotherapy service have a hearing case history of risk factors and hearing alterations prior to exposure to potentially-ototoxic drugs.<\/jats:p>","DOI":"10.1055\/s-0046-1819640","type":"journal-article","created":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T22:49:42Z","timestamp":1777589382000},"page":"001-008","source":"Crossref","is-referenced-by-count":0,"title":["Hearing Characteristics of Adults before Exposure to Potentially Ototoxic Chemotherapy"],"prefix":"10.1055","volume":"30","author":[{"ORCID":"https:\/\/orcid.org\/0009-0008-9672-2839","authenticated-orcid":false,"given":"Cec\u00edlia Vieira","family":"Peruch","sequence":"additional","affiliation":[{"name":"Speech Therapy Department, Universidade Federal de Ci\u00eancias da Sa\u00fade de Porto Alegre (UFCSPA), Porto Alegre, RS, Brazil"},{"name":"Speech Therapy Department, Santa Casa de Porto Alegre, Porto Alegre, RS, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8325-9082","authenticated-orcid":false,"given":"Vera Beatris","family":"Martins","sequence":"additional","affiliation":[{"name":"Speech Therapy Department, Universidade Federal de Ci\u00eancias da Sa\u00fade de Porto Alegre (UFCSPA), Porto Alegre, RS, Brazil"},{"name":"Speech Therapy Department, Santa Casa de Porto Alegre, Porto Alegre, RS, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9967-9719","authenticated-orcid":false,"given":"Felipe de Oliveira","family":"Goulart","sequence":"additional","affiliation":[{"name":"Speech Therapy Department, Universidade Federal de Ci\u00eancias da Sa\u00fade de Porto Alegre (UFCSPA), Porto Alegre, RS, Brazil"},{"name":"Speech Therapy Department, Santa Casa de Porto Alegre, Porto Alegre, RS, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8739-8976","authenticated-orcid":false,"given":"Marcia Salgado","family":"Machado","sequence":"additional","affiliation":[{"name":"Speech Therapy Department, Universidade Federal de Ci\u00eancias da Sa\u00fade de Porto Alegre (UFCSPA), Porto Alegre, RS, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6586-2080","authenticated-orcid":false,"given":"Eliane","family":"Dallegrave","sequence":"additional","affiliation":[{"name":"Department of Pharmacosciences, Universidade Federal de Ci\u00eancias da Sa\u00fade de Porto Alegre (UFCSPA), Porto Alegre, RS, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7837-629X","authenticated-orcid":false,"given":"Monalise Costa Batista","family":"Berbert","sequence":"additional","affiliation":[{"name":"Speech Therapy Department, Universidade Federal de Ci\u00eancias da Sa\u00fade de Porto Alegre (UFCSPA), Porto Alegre, RS, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2026,4,30]]},"reference":[{"issue":"02","key":"ref1","doi-asserted-by":"publisher","first-page":"59","DOI":"10.7874\/jao.2017.00360","article-title":"Ototoxicity: A challenge in diagnosis and treatment","volume":"22","author":"P Ganesan","year":"2018","journal-title":"J Audiol Otol"},{"issue":"10","key":"ref2","doi-asserted-by":"publisher","first-page":"4677","DOI":"10.1007\/s00405-021-07225-2","article-title":"Long-term auditory follow-up in the management of pediatric platinum-induced ototoxicity","volume":"279","author":"A R Fetoni","year":"2022","journal-title":"Eur Arch Otorhinolaryngol"},{"issue":"02","key":"ref3","doi-asserted-by":"publisher","first-page":"196","DOI":"10.1055\/s-0031-1277242","article-title":"Detection of ototoxicity","volume":"32","author":"K 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