{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T17:48:41Z","timestamp":1790790521430,"version":"4.1.0"},"reference-count":10,"publisher":"Georg Thieme Verlag KG","issue":"02","license":[{"start":{"date-parts":[[2026,5,11]],"date-time":"2026-05-11T00:00:00Z","timestamp":1778457600000},"content-version":"vor","delay-in-days":40,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Avicenna J Med"],"published-print":{"date-parts":[[2026,4]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Low-grade fibromyxoid sarcoma (LGFMS) is an uncommon soft tissue tumor that often masquerades as benign due to its deceptively mild histopathological appearance. Predominantly arising from the deep soft tissues of the extremities and trunk, LGFMS is exceptionally uncommon in the gastrointestinal (GI) tract. While most documented cases have been found in the small intestine and colon, only one prior case has been reported in the stomach involving an elderly Japanese woman. In this report, we present a compelling case of gastric LGFMS in a 21-year-old female who experienced mild hematemesis and fatigue. An abdominal computed tomography scan unveiled an ill-defined, hypodense mass originating from the lesser curvature of the stomach and extending toward the left hepatic lobe\u2014highlighting the complexity of this condition. Further investigation included an upper endoscopy and an incomplete laparoscopic resection of the tumor. Histopathological analysis revealed a proliferation of spindle cells with focal whorling within a heavily collagenized stroma, transitioning abruptly to a myxoid area, thus confirming a diagnosis of LGFMS. Immunohistochemical testing showed positive results for vimentin and BCL2. Crucially, molecular analysis identified the FUS-CREB3L1 fusion. Based on our search in the literature review, this case is considered a second instance reported in English literature.<\/jats:p>","DOI":"10.1055\/s-0046-1820425","type":"journal-article","created":{"date-parts":[[2026,5,11]],"date-time":"2026-05-11T23:14:37Z","timestamp":1778541277000},"page":"093-095","source":"Crossref","is-referenced-by-count":1,"title":["Low-Grade Gastric Fibromyxoid Sarcoma in an Adult Female: A Rare Case Report"],"prefix":"10.1055","volume":"16","author":[{"given":"Duaa","family":"Al-shurbaji","sequence":"additional","affiliation":[{"name":"Department of Histopathology, King Hussein Medical Center, Jordanian Royal Medical Services, Amman, Jordan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Muna","family":"AL-Khawaldeh","sequence":"additional","affiliation":[{"name":"Department of Oncology, King Hussein Medical Center, Jordanian Royal Medical Services, Amman, Jordan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Layth H.","family":"Zraygat","sequence":"additional","affiliation":[{"name":"Department of Oncology, King Hussein Medical Center, Jordanian Royal Medical Services, Amman, Jordan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1368-7775","authenticated-orcid":false,"given":"Mohammad","family":"Al-Slehat","sequence":"additional","affiliation":[{"name":"Department of Medicine, Jordan University Hospital, Amman, Jordan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rula","family":"Al-Shimi","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Jordan University of Science and Technology, Irbid, Jordan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2026,5,11]]},"reference":[{"issue":"05","key":"ref1","doi-asserted-by":"crossref","first-page":"615","DOI":"10.1093\/ajcp\/88.5.615","article-title":"Low-grade fibromyxoid sarcoma. A report of two metastasizing neoplasms having a deceptively benign appearance","volume":"88","author":"H L Evans","year":"1987","journal-title":"Am J Clin Pathol"},{"issue":"03","key":"ref2","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1111\/j.1365-2559.1995.tb01436.x","article-title":"Low grade fibromyxoid sarcoma: clinicopathological analysis of eleven new cases in support of a distinct entity","volume":"26","author":"J R Goodlad","year":"1995","journal-title":"Histopathology"},{"issue":"04","key":"ref3","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1007\/s11604-007-0214-7","article-title":"Low-grade fibromyxoid sarcoma of the small bowel mesentery: computed tomography and magnetic resonance imaging findings","volume":"26","author":"S Fujii","year":"2008","journal-title":"Radiat Med"},{"issue":"03","key":"ref4","doi-asserted-by":"crossref","first-page":"274","DOI":"10.1016\/j.dld.2006.01.015","article-title":"Low-grade fibromyxoid sarcoma of the colon","volume":"39","author":"I J Park","year":"2007","journal-title":"Dig Liver Dis"},{"issue":"07","key":"ref5","doi-asserted-by":"crossref","first-page":"1069","DOI":"10.1097\/PAS.0b013e31821bc17a","article-title":"Low-grade fibromyxoid sarcoma of the small intestine: report of 4 cases with molecular cytogenetic confirmation","volume":"35","author":"J A Laurini","year":"2011","journal-title":"Am J Surg Pathol"},{"issue":"03","key":"ref6","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1002\/iju5.12718","article-title":"Retroperitoneal low-grade fibromyxoid sarcoma","volume":"7","author":"T Noguchi","year":"2024","journal-title":"IJU Case Rep"},{"issue":"04","key":"ref7","doi-asserted-by":"crossref","first-page":"873","DOI":"10.1016\/j.joms.2009.04.136","article-title":"Low-grade fibromyxoid sarcoma: clinical study and case report","volume":"68","author":"Z Tang","year":"2010","journal-title":"J Oral Maxillofac Surg"},{"issue":"03","key":"ref8","doi-asserted-by":"crossref","first-page":"219","DOI":"10.5114\/pjp.2018.79541","article-title":"Low-grade fibromyxoid sarcoma of the extremities: a clinicopathologic study of 24 cases and review of the literature","volume":"69","author":"A Sambri","year":"2018","journal-title":"Pol J Pathol"},{"issue":"09","key":"ref9","doi-asserted-by":"crossref","first-page":"1358","DOI":"10.5858\/2006-130-1358-LFSABR","article-title":"Low-grade fibromyxoid sarcoma: a brief review","volume":"130","author":"S E Vernon","year":"2006","journal-title":"Arch Pathol Lab Med"},{"issue":"11","key":"ref10","first-page":"51","article-title":"Human pathology: case reports primary gastric low-grade fibromyxoid sarcoma with FUS-CREB3L1 fusion \u2013 a hitherto undescribed origin of Evans tumor","volume":"2018","author":"Y Tsukamoto","year":"2017","journal-title":"Hum Pathol Case Reports [Internet]"}],"container-title":["Avicenna Journal of Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/s-0046-1820425.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,10]],"date-time":"2026-07-10T22:43:19Z","timestamp":1783723399000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/s-0046-1820425"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4]]},"references-count":10,"journal-issue":{"issue":"02","published-online":{"date-parts":[[2026,7,10]]},"published-print":{"date-parts":[[2026,4]]}},"URL":"https:\/\/doi.org\/10.1055\/s-0046-1820425","archive":["Portico","CLOCKSS"],"relation":{},"ISSN":["2231-0770","2249-4464"],"issn-type":[{"value":"2231-0770","type":"print"},{"value":"2249-4464","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,4]]}}}