{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T19:52:37Z","timestamp":1792785157533,"version":"4.5.0"},"reference-count":10,"publisher":"Georg Thieme Verlag KG","issue":"03","license":[{"start":{"date-parts":[[2026,5,16]],"date-time":"2026-05-16T00:00:00Z","timestamp":1778889600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Zhejiang Medical Health Science and Technology Project","award":["2023KY773"],"award-info":[{"award-number":["2023KY773"]}]},{"name":"Zhejiang Medical Health Science and Technology Project","award":["2022KY796"],"award-info":[{"award-number":["2022KY796"]}]},{"name":"National Natural Science Foundation of China","award":["81301243"],"award-info":[{"award-number":["81301243"]}],"id":[{"id":"https:\/\/ror.org\/01h0zpd94","id-type":"ROR","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["World J Nucl Med"],"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Phosphaturic mesenchymal tumor (PMT) is an uncommon neoplasm and the leading cause of tumor-induced osteomalacia (TIO). We report a 55-year-old woman with a 2-year history of progressive hip pain and hypophosphatemia. Laboratory findings demonstrated renal phosphate wasting. Conventional imaging revealed a small soft-tissue nodule in the right thigh, and 18F-AlF-NOTA-octreotide (18F-OC) PET\/CT (positron emission tomography\/computed tomography) showed intense radiotracer uptake, accurately localizing the culprit lesion. Surgical excision confirmed a PMT, and serum phosphate levels normalized postoperatively with resolution of symptoms. This case highlights the diagnostic value of 18F-OC PET\/CT in detecting small PMTs and underscores the importance of considering TIO in patients with persistent hypophosphatemia and unexplained musculoskeletal symptoms.<\/jats:p>","DOI":"10.1055\/s-0046-1823003","type":"journal-article","created":{"date-parts":[[2026,5,16]],"date-time":"2026-05-16T22:32:06Z","timestamp":1778970726000},"page":"255-257","source":"Crossref","is-referenced-by-count":0,"title":["18F-OC PET\/CT Localization of a Phosphaturic Mesenchymal Tumor Presenting with Tumor-Induced Osteomalacia"],"prefix":"10.1055","volume":"25","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0516-6467","authenticated-orcid":false,"given":"Haifeng","family":"Hou","sequence":"additional","affiliation":[{"name":"Department of Nuclear Medicine, Zhejiang University School of Medicine, The Second Affiliated Hospital, Hangzhou, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lijun","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Nuclear Medicine, Zhejiang University School of Medicine, The Second Affiliated Hospital, Hangzhou, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaofeng","family":"Zhou","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology, Zhejiang University School of Medicine, The Second Affiliated Hospital, Hangzhou, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2026,5,16]]},"reference":[{"issue":"08","key":"ref1","doi-asserted-by":"crossref","first-page":"1442","DOI":"10.1002\/1097-0142(19870415)59:8<1442::AID-CNCR2820590810>3.0.CO;2-Q","article-title":"Phosphaturic mesenchymal tumors. A polymorphous group causing osteomalacia or rickets","volume":"59","author":"N Weidner","year":"1987","journal-title":"Cancer"},{"issue":"01","key":"ref2","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1097\/00000478-200401000-00001","article-title":"Most osteomalacia-associated mesenchymal tumors are a single histopathologic entity: an analysis of 32 cases and a comprehensive review of the literature","volume":"28","author":"A L Folpe","year":"2004","journal-title":"Am J Surg Pathol"},{"issue":"07","key":"ref3","doi-asserted-by":"crossref","first-page":"675","DOI":"10.1507\/endocrj.EJ16-0587","article-title":"The diagnostic dilemma of tumor induced osteomalacia: a retrospective analysis of 144 cases","volume":"64","author":"J Feng","year":"2017","journal-title":"Endocr J"},{"issue":"03","key":"ref4","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1007\/s12149-021-01575-x","article-title":"Diagnostic performance of 68Ga-DOTATOC PET\/CT in tumor-induced osteomalacia","volume":"35","author":"A Kato","year":"2021","journal-title":"Ann Nucl Med"},{"issue":"02","key":"ref5","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1210\/endrev\/bnac026","article-title":"Tumor-induced osteomalacia: a comprehensive review","volume":"44","author":"S Minisola","year":"2023","journal-title":"Endocr Rev"},{"issue":"12","key":"ref6","doi-asserted-by":"crossref","first-page":"2711","DOI":"10.1016\/j.humpath.2013.07.016","article-title":"Phosphaturic mesenchymal tumors show positive staining for somatostatin receptor 2A (SSTR2A)","volume":"44","author":"M Houang","year":"2013","journal-title":"Hum Pathol"},{"issue":"03","key":"ref7","doi-asserted-by":"crossref","first-page":"R53","DOI":"10.1530\/ERC-11-0006","article-title":"Tumor-induced osteomalacia","volume":"18","author":"W H Chong","year":"2011","journal-title":"Endocr Relat Cancer"},{"key":"ref8","doi-asserted-by":"crossref","first-page":"5172131","DOI":"10.1155\/2021\/5172131","article-title":"TIO Associated with hyperparathyroidism: a rarity, a rule, or a novel HPT-PMT syndrome-a case study with literature review","volume":"2021","author":"M Salim","year":"2021","journal-title":"Case Rep Endocrinol"},{"issue":"01","key":"ref9","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1007\/s00256-018-3014-5","article-title":"Imaging features of phosphaturic mesenchymal tumors","volume":"48","author":"S M Broski","year":"2019","journal-title":"Skeletal Radiol"},{"issue":"01","key":"ref10","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1186\/s13550-023-01003-3","article-title":"Prospective comparison of [18F]AlF-NOTA-octreotide PET\/MRI to [68Ga]Ga-DOTATATE PET\/CT in neuroendocrine tumor patients","volume":"13","author":"L Boeckxstaens","year":"2023","journal-title":"EJNMMI Res"}],"container-title":["World Journal of Nuclear Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/s-0046-1823003.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T22:30:56Z","timestamp":1790289056000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/s-0046-1823003"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5,16]]},"references-count":10,"journal-issue":{"issue":"03","published-online":{"date-parts":[[2026,9,24]]},"published-print":{"date-parts":[[2026,9]]}},"URL":"https:\/\/doi.org\/10.1055\/s-0046-1823003","archive":["Portico","CLOCKSS"],"relation":{},"ISSN":["1450-1147","1607-3312"],"issn-type":[{"value":"1450-1147","type":"print"},{"value":"1607-3312","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,5,16]]}}}