{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:13:00Z","timestamp":1788221580852,"version":"build-2803163510"},"reference-count":66,"publisher":"Georg Thieme Verlag KG","issue":"06","license":[{"start":{"date-parts":[[2026,8,31]],"date-time":"2026-08-31T00:00:00Z","timestamp":1788134400000},"content-version":"vor","delay-in-days":91,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Arq Neuropsiquiatr"],"published-print":{"date-parts":[[2026,6]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Behavioral change remains challenging despite a vast body of evidence linking health behaviors with several health outcomes. Over the past few decades, various health-behavior change theories and techniques have emerged, leading to significant advances in the field. However, although some existing theories provide competent models to structure behavioral-change approaches, they do not provide a unified neurobiological foundation.<\/jats:p>\n                  <jats:p>To outline the connections between neuroscientific foundations and behavioral-change theories and to provide an overarching neuroscientific perspective.<\/jats:p>\n                  <jats:p>We conducted a structured narrative review based on data retrieved from major biomedical databases and authoritative neuroscience textbooks to integrate neuroscience data with behavioral-change theories.<\/jats:p>\n                  <jats:p>We describe the neuroscience of behavior from neuroanatomical to neurophysiological mechanisms, emphasizing four brain systems: the hypothalamus, the amygdala, the mesocorticolimbic system, and the prefrontal cortex. Finally, we integrate these mechanisms with a neuroscience-based motivational theory called the Behavior Change Resource Model.<\/jats:p>\n                  <jats:p>The present work integrates established neurobiological knowledge and behavioral-change theories, providing a framework to link theory and health-behavior interventions.<\/jats:p>","DOI":"10.1055\/s-0046-1825762","type":"journal-article","created":{"date-parts":[[2026,8,31]],"date-time":"2026-08-31T23:12:50Z","timestamp":1788217970000},"page":"001-014","source":"Crossref","is-referenced-by-count":0,"title":["Behavioral change: from neurobiology to behavioral-change theories and back \u2013 part 1"],"prefix":"10.1055","volume":"84","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3220-7746","authenticated-orcid":false,"given":"Conrado Regis","family":"Borges","sequence":"additional","affiliation":[{"name":"Faculdade S\u00edrio-Liban\u00eas, S\u00e3o Paulo SP, Brazil."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4838-2840","authenticated-orcid":false,"given":"Fabiano Moulin de","family":"Moraes","sequence":"additional","affiliation":[{"name":"Universidade Federal de S\u00e3o Paulo, Departamento de Neurologia, S\u00e3o Paulo SP, Brazil."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4742-7402","authenticated-orcid":false,"given":"Marcelo","family":"Youngblood","sequence":"additional","affiliation":[{"name":"Universidade Estadual de Ponta Grossa, Ponta Grossa PR, Brazil."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4316-9389","authenticated-orcid":false,"given":"Felipe Chaves Duarte","family":"Barros","sequence":"additional","affiliation":[{"name":"Universidade Federal de S\u00e3o Paulo, Departamento de Neurologia, S\u00e3o Paulo SP, Brazil."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-8151-3002","authenticated-orcid":false,"given":"Nancy","family":"Huang","sequence":"additional","affiliation":[{"name":"Universidade de S\u00e3o Paulo, Departamento de Neurologia, S\u00e3o Paulo SP, Brazil."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0405-7157","authenticated-orcid":false,"given":"Marcos Christiano","family":"Lange","sequence":"additional","affiliation":[{"name":"Universidade Federal do Paran\u00e1, Departamento de Neurologia, Curitiba PR, Brazil."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2026,8,31]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"572","DOI":"10.1016\/S0140-6736(24)01296-0","article-title":"Dementia prevention, intervention, and care: 2024 report of the Lancet standing Commission","volume":"404","author":"G Livingston","year":"2024","journal-title":"Lancet"},{"issue":"05","key":"ref2","doi-asserted-by":"publisher","first-page":"e18","DOI":"10.1161\/CIR.0000000000001078","article-title":"Life's Essential 8: Updating and Enhancing the American Heart Association's Construct of Cardiovascular Health: A Presidential Advisory from the American Heart Association","volume":"146","author":"D M Lloyd-Jones","year":"2022"},{"issue":"08","key":"ref3","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1055\/s-0045-1811234","article-title":"Brain health: a new concept to the neurologist - 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