{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,17]],"date-time":"2026-01-17T23:21:37Z","timestamp":1768692097772,"version":"3.49.0"},"reference-count":0,"publisher":"Georg Thieme Verlag KG","issue":"S 01","license":[{"start":{"date-parts":[[2021,4,30]],"date-time":"2021-04-30T00:00:00Z","timestamp":1619740800000},"content-version":"vor","delay-in-days":29,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Laryngorhinootologie"],"published-print":{"date-parts":[[2021,4]]},"abstract":"<jats:p>Seltene Erkrankungen stellen betroffene Patienten, ihre Angeh\u00f6rigen,\n                    \u00c4rzte, Pflegkr\u00e4fte und Therapeuten oft vor besondere\n                    Herausforderungen. Ihre Seltenheit erschwert aus medizinischen und\n                    \u00f6konomischen Gr\u00fcnden h\u00e4ufig die Forschung und die\n                    medizinische Versorgung der betroffenen Patientinnen und Patienten. Die\n                    komplexen Probleme, die mit der Diagnostik, Erforschung und Therapie seltener\n                    Erkrankungen verbunden sind, wurden 1992 auf sehr bewegende Weise dem\n                    Kinopublikum im Hollywood-Film \u201eLorenzos \u00d6l\u201c dargelegt.\n                    Der Regisseur George Miller verfilmte hier das reale Schicksal eines kleinen\n                    Jungen, Lorenzo Michael Murphy Odone, bei dem 1984 im Alter von sechs Jahren die\n                    seltene Nervenkrankheit Adrenoleukodystrophie (ALD) diagnostiziert worden war.\n                    Zahlreiche der vielf\u00e4ltigen Probleme mit seltenen Erkrankungen, die im\n                    Film dargestellt werden, existieren noch heute. Insbesondere in den letzten\n                    Jahren sind jedoch die seltenen Erkrankungen immer mehr in das Licht der\n                    \u00f6ffentlichen Aufmerksamkeit ger\u00fcckt.<\/jats:p>","DOI":"10.1055\/s-1397-0832","type":"journal-article","created":{"date-parts":[[2021,4,30]],"date-time":"2021-04-30T23:32:31Z","timestamp":1619825551000},"page":"S1-S1","source":"Crossref","is-referenced-by-count":2,"special_numbering":"S","title":["Editorial"],"prefix":"10.1055","volume":"100","author":[{"given":"Stefan K.","family":"Plontke","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"194","published-online":{"date-parts":[[2021,4,30]]},"container-title":["Laryngo-Rhino-Otologie"],"original-title":[],"language":"de","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/s-1397-0832.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,8,31]],"date-time":"2022-08-31T08:01:53Z","timestamp":1661932913000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/s-1397-0832"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,4]]},"references-count":0,"journal-issue":{"issue":"S 01","published-online":{"date-parts":[[2021,4,30]]},"published-print":{"date-parts":[[2021,4]]}},"URL":"https:\/\/doi.org\/10.1055\/s-1397-0832","archive":["Portico","CLOCKSS"],"relation":{},"ISSN":["0935-8943","1438-8685"],"issn-type":[{"value":"0935-8943","type":"print"},{"value":"1438-8685","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,4]]}}}