{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,7]],"date-time":"2026-04-07T22:14:55Z","timestamp":1775600095516,"version":"3.50.1"},"reference-count":0,"publisher":"Georg Thieme Verlag KG","issue":"12","license":[{"start":{"date-parts":[[2019,11,25]],"date-time":"2019-11-25T00:00:00Z","timestamp":1574640000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Endosc Int Open"],"published-print":{"date-parts":[[2019,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>\n          Background and study aims\u2002A variety of endoscopic techniques are currently available for treatment of upper gastrointestinal (UGI) anastomotic leaks; however, no definite consensus exists on the most appropriate therapeutic approach. Our aim was to explore current management of UGI anastomotic leaks. <\/jats:p><jats:p>\n          Methods\u2002A survey questionnaire was distributed among international expert therapeutic endoscopists regarding management of UGI anastomotic leaks. <\/jats:p><jats:p>\n          Results\u2002A total of 44\u200a% of 163 surveys were returned; 69\u200a% were from gastroenterologists and 56\u200a% had &gt;\u200a10 years of experience. A third of respondents treat between 10 and 19 patients annually. Fifty-six percent use fully-covered self-expandable metal stents as their usual first option; 80% use techniques to minimize migration; 4 weeks was the most common reported stent dwell time. Sixty percent perform epithelial ablation prior to over-the-scope-clip placement or suturing. Regarding endoscopic vacuum therapy (EVT), 56\u200a% perform balloon dilation and intracavitary EVT in patients with large cavities but small leak defects. Regarding endoscopic septotomy, 56\u200a% consider a minimal interval of 4 weeks from surgery and 90\u200a% consider the need to perform further sessions. Regarding endoscopic internal drainage (EID), placement of two stents and shorter stents is preferred. Persistent inflammation with clinical sepsis was the definition most commonly reported for endoscopic failure. EVT\/stent placement and EVT\/EID were the therapeutic options most often chosen in patients with previous oncologic surgery and previous bariatric surgery, respectively. <\/jats:p><jats:p>\n          Conclusions\u2002There is a wide variation in the management of patients with UGI anastomotic leaks. Future prospective studies are needed to move from an expert- to evidence- and personalization-based care.<\/jats:p>","DOI":"10.1055\/a-1005-6632","type":"journal-article","created":{"date-parts":[[2019,11,25]],"date-time":"2019-11-25T18:40:07Z","timestamp":1574707207000},"page":"E1671-E1682","source":"Crossref","is-referenced-by-count":40,"title":["International multicenter expert survey on endoscopic treatment of upper gastrointestinal anastomotic leaks"],"prefix":"10.1055","volume":"07","author":[{"given":"Eduardo","family":"Rodrigues-Pinto","sequence":"additional","affiliation":[{"name":"Gastroenterology Department, Centro Hospitalar S\u00e3o Jo\u00e3o, Porto, Portugal"}]},{"given":"Alessandro","family":"Repici","sequence":"additional","affiliation":[{"name":"Digestive Endoscopy Unit, Humanitas Research Hospital, Rozzano, Milan; Humanitas University, Rozzano, Milan, Italy"}]},{"given":"Gianfranco","family":"Donatelli","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology, H\u00f4pital Priv\u00e9 des Peupliers Paris, France"}]},{"given":"Guilherme","family":"Macedo","sequence":"additional","affiliation":[{"name":"Gastroenterology Department, Centro Hospitalar S\u00e3o Jo\u00e3o, Porto, Portugal"}]},{"given":"Jacques","family":"Devi\u00e8re","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology Hepatopancreatology, and Digestive Oncology, Erasme University Hospital, Universit\u00e9 Libre de Bruxelles, Brussels, Belgium"}]},{"given":"Jeanin E.","family":"van Hooft","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology, Amsterdam University Medical Center, University of Amsterdam, Amsterdam, The Netherlands"}]},{"given":"Josemberg M.","family":"Campos","sequence":"additional","affiliation":[{"name":"Department of Surgery, University of Pernambuco, Recife, Pernambuco, Brazil"}]},{"given":"Manoel","family":"Galvao Neto","sequence":"additional","affiliation":[{"name":"Herbert Wertheim College of Medicine at Florida International University, Department of Surgery, Miami, Florida, United States"}]},{"given":"Marco","family":"Silva","sequence":"additional","affiliation":[{"name":"Gastroenterology Department, Centro Hospitalar S\u00e3o Jo\u00e3o, Porto, Portugal"}]},{"given":"Pierre","family":"Eisendrath","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology & Hepatology, CHU Saint Pierre, Universit\u00e9 Libre de Bruxelles, Brussels, Belgium"}]},{"given":"Vivek","family":"Kumbhari","sequence":"additional","affiliation":[{"name":"Department of Medicine and Division of Gastroenterology and Hepatology, The Johns Hopkins Medical Institutions, Baltimore, Maryland, United States"}]},{"given":"Mouen A.","family":"Khashab","sequence":"additional","affiliation":[{"name":"Department of Medicine and Division of Gastroenterology and Hepatology, The Johns Hopkins Medical Institutions, Baltimore, Maryland, United States"}]}],"member":"194","published-online":{"date-parts":[[2019,11,25]]},"container-title":["Endoscopy International Open"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/a-1005-6632.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,11,25]],"date-time":"2019-11-25T18:40:14Z","timestamp":1574707214000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/a-1005-6632"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,11,25]]},"references-count":0,"journal-issue":{"issue":"12","published-online":{"date-parts":[[2019,11,25]]},"published-print":{"date-parts":[[2019,12]]}},"URL":"https:\/\/doi.org\/10.1055\/a-1005-6632","relation":{},"ISSN":["2364-3722","2196-9736"],"issn-type":[{"value":"2364-3722","type":"print"},{"value":"2196-9736","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,11,25]]}}}