{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,7,30]],"date-time":"2024-07-30T16:31:53Z","timestamp":1722357113303},"reference-count":44,"publisher":"Georg Thieme Verlag KG","issue":"01","license":[{"start":{"date-parts":[[2020,12,17]],"date-time":"2020-12-17T00:00:00Z","timestamp":1608163200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Sports Med Int Open"],"published-print":{"date-parts":[[2021,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Intensive physical training programs can affect the immune system. This study aims to verify the multi-micronutrient supplementation effects on serum immunoglobulins levels prior to and after a five-week physical training program. Twenty-four male recruit firefighters were randomly allocated into supplemented (with Prisfar Ever-Fit Plus over 35 consecutive days) and placebo groups (n=12 each). Serum immunoglobulins G, A, and M were assessed. Supplementation effect was detected for immunoglobulin G (eta-squared, \u03b72: 0.09; p=0.035; power: 0.56), A (\u03b72: 0.24; p=0.001; power: 0.95), and M (\u03b72: 0.09; p=0.036; power: 0.56). Although immunoglobulin A was different between groups at baseline (mean difference: 42.58; 95%CI: 7.00 to 78.16\u2009mg\/dL; p=0.021; d=2.48), within-group (before vs. after five weeks) showed no differences for both supplemented and control groups. In addition, even if immunoglobulin G and M were similar at baseline, immunoglobulin G decreased (mean diff.: 46.4; 95%CI: 6.7 to 86.1\u2009mg\/dL; p=0.03; d=0.74) and immunoglobulin M increased (mean diff.: \u221210.7; 95%CI: \u221215.8 to \u22125.5\u2009mg\/dL; p=0.001; d=\u22121.33) in the control group. Although mean values remained within the reference values, changes observed for immunoglobulin G and M may reflect some immune protection for firefighters engaged in recruit training.<\/jats:p>","DOI":"10.1055\/a-1296-1486","type":"journal-article","created":{"date-parts":[[2020,12,18]],"date-time":"2020-12-18T02:12:53Z","timestamp":1608257573000},"page":"E1-E7","source":"Crossref","is-referenced-by-count":1,"title":["Multi-Micronutrient Supplementation and Immunoglobulin Response in Well-Fed Firefighters"],"prefix":"10.1055","volume":"05","author":[{"given":"Jos\u00e9 Augusto Rodrigues","family":"Santos","sequence":"additional","affiliation":[{"name":"Centre of Research, Education, Innovation and Intervention in Sport (CIFI2D), Faculty of Sport, University of Porto, Porto, Portugal"}]},{"given":"Ricardo J.","family":"Fernandes","sequence":"additional","affiliation":[{"name":"Centre of Research, Education, Innovation and Intervention in Sport (CIFI2D), Faculty of Sport, University of Porto, Porto, Portugal"},{"name":"Porto Biomechanics Laboratory (LABIOMEP\u2011UP), University of Porto, Porto, Portugal"}]},{"given":"Rodrigo","family":"Zacca","sequence":"additional","affiliation":[{"name":"Centre of Research, Education, Innovation and Intervention in Sport (CIFI2D), Faculty of Sport, University of Porto, Porto, Portugal"},{"name":"Porto Biomechanics Laboratory (LABIOMEP\u2011UP), University of Porto, Porto, Portugal"},{"name":"Ministry of Education, CAPES Foundation, Brazilia, Brazil"}]}],"member":"194","published-online":{"date-parts":[[2020,12,17]]},"reference":[{"key":"ref1","first-page":"207","article-title":"Differences in the cellular and humoral immune system between middle-aged men with different intensity and duration of physically training","volume":"44","author":"G Buyukyazi","year":"2004","journal-title":"J Sports Med Phys 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