{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T15:26:26Z","timestamp":1789658786696,"version":"4.0.1"},"reference-count":63,"publisher":"Georg Thieme Verlag KG","funder":[{"name":"Bundesministerium f\u00fcr Bildung und\nForschung","award":["01GL1703 A\u2011C"],"award-info":[{"award-number":["01GL1703 A\u2011C"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rehabilitation (Stuttg)"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Knowledge about the development of functioning in older age is crucial to\ndesign targeted interventions to maintain good health in older adults. The\naim of this study was to investigate the time-trajectories of functioning\nand its domains (Cognition, Mobility, Self-Care, Getting along, Life\nActivities, and Participation) over time in a community sample of older\npeople with chronic health conditions. Additionally, the study sought to\nidentify factors differentially associated with these trajectories.<\/jats:p>\n                  <jats:p>A total of n=491 individuals aged 65 years and older with chronic health\nconditions answered the WHO Disability Assessment Schedule 2.0 questionnaire\nthree times over a 1.5-year period (at T2 n=309). Linear Mixed Effects\nModels and pairwise comparisons of the slopes of the questionnaires\ndifferent subscales were used to analyse trajectories over time and to\nidentify associated factors.<\/jats:p>\n                  <jats:p>The results revealed a general decline in functioning over time across all\ndomains, with the exception of Participation. Significant differences were\nobserved between the trajectory coefficients of certain domains. While\ndepressive symptoms displayed comparable associations with all domains of\nfunctioning, gender and age exhibited divergent associations with\nfunctioning across domains.<\/jats:p>\n                  <jats:p>The results emphasize the importance of a nuanced understanding of how\nfunctioning develops across different domains in older age. This can\ncontribute to targeted prevention and support programs for older adults at\nrisk and help maintain good health in older age among those with chronic\nconditions.<\/jats:p>","DOI":"10.1055\/a-2892-2251","type":"journal-article","created":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T22:56:42Z","timestamp":1789513002000},"source":"Crossref","is-referenced-by-count":0,"title":["Functioning in Older Adults with Chronic Diseases: Trajectories and\nAssociated Factors"],"prefix":"10.1055","author":[{"ORCID":"https:\/\/orcid.org\/0009-0008-0593-2807","authenticated-orcid":false,"given":"Lara Caroline","family":"Hille","sequence":"additional","affiliation":[{"name":"University Medical Center\nHamburg-Eppendorf, Germany","place":["Hamburg"],"department":["Department of Child and Adolescent Psychiatry and\nPsychotherapy"]},{"name":"Medical Center \u2013 University of Freiburg, Germany","place":["Freiburg"],"department":["Section of Health Care Research and Rehabilitation Research, Institute\nof Medical Biometry and Statistics"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lukas","family":"Horstmeier","sequence":"additional","affiliation":[{"name":"Medical Center \u2013 University of Freiburg, Germany","place":["Freiburg"],"department":["Section of Health Care Research and Rehabilitation Research, Institute\nof Medical Biometry and Statistics"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gloria","family":"Metzner","sequence":"additional","affiliation":[{"name":"Medical Center \u2013 University of Freiburg, Germany","place":["Freiburg"],"department":["Section of Health Care Research and Rehabilitation Research, Institute\nof Medical Biometry and Statistics"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin","family":"H\u00e4rter","sequence":"additional","affiliation":[{"name":"University Medical Center\nHamburg-Eppendorf, Germany","place":["Hamburg"],"department":["Department of Medical Psychology"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6867-0316","authenticated-orcid":false,"given":"Erik","family":"Farin-Glattacker","sequence":"additional","affiliation":[{"name":"Medical Center \u2013 University of Freiburg, Germany","place":["Freiburg"],"department":["Section of Health Care Research and Rehabilitation Research, Institute\nof Medical Biometry and Statistics"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"194","published-online":{"date-parts":[[2026,9,15]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","first-page":"afac147","DOI":"10.1093\/ageing\/afac147","article-title":"The UN Decade of healthy ageing: strengthening measurement for\nmonitoring health and wellbeing of older people","volume":"51","author":"J Amuthavalli Thiyagarajan","year":"2022","journal-title":"Age\nAgeing"},{"key":"ref2","doi-asserted-by":"publisher","first-page":"2145","DOI":"10.1016\/S0140-6736(15)00516-4","article-title":"The World report on ageing and health: a policy framework for healthy\nageing","volume":"387","author":"J R Beard","year":"2016","journal-title":"The Lancet"},{"key":"ref3","doi-asserted-by":"publisher","first-page":"563","DOI":"10.1016\/S0140-6736(14)61462-8","article-title":"Health, functioning, and disability in older adults\u2014present status and future\nimplications","volume":"385","author":"S Chatterji","year":"2015","journal-title":"The Lancet"},{"key":"ref4","doi-asserted-by":"publisher","first-page":"2602","DOI":"10.1001\/archinte.161.21.2602","article-title":"Functional Disability and Health Care Expenditures for Older Persons","volume":"161","author":"T R Fried","year":"2001","journal-title":"Arch Intern Med"},{"key":"ref5","doi-asserted-by":"publisher","first-page":"441","DOI":"10.1007\/s00103-010-1052-9","article-title":"Herausforderungen an die Gesundheitsforschung f\u00fcr eine alternde Gesellschaft am\nBeispiel \u201eMultimorbidit\u00e4t\u201c","volume":"53","author":"C Scheidt-Nave","year":"2010","journal-title":"Bundesgesundheitsblatt - Gesundheitsforschung -\nGesundheitsschutz"},{"key":"ref7","doi-asserted-by":"publisher","first-page":"e0248844","DOI":"10.1371\/journal.pone.0248844","article-title":"Trajectories of healthy ageing among older adults with\nmultimorbidity: A growth mixture model using harmonised data from eight ATHLOS\ncohorts","volume":"16","author":"H Nguyen","year":"2021","journal-title":"PLOS ONE"},{"key":"ref8","doi-asserted-by":"publisher","first-page":"880","DOI":"10.1093\/ije\/dyaa236","article-title":"Development of a common scale for measuring healthy ageing across the world:\nResults from the ATHLOS consortium","volume":"50","author":"A Sanchez-Niubo","year":"2021","journal-title":"Int J Epidemiol"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.23736\/S1973-9087.22.07509-8","article-title":"Rehabilitation definition for research purposes. 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