{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T22:07:03Z","timestamp":1740175623320,"version":"3.37.3"},"reference-count":0,"publisher":"Georg Thieme Verlag KG","issue":"02","license":[{"start":{"date-parts":[[2020,4,27]],"date-time":"2020-04-27T00:00:00Z","timestamp":1587945600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Arquivos Brasileiros de Neurocirurgia: Brazilian Neurosurgery"],"published-print":{"date-parts":[[2020,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>\n          Object\u2003The timing of definitive management of ruptured intracranial aneurysms has been the subject of considerable debate, although the benefits of early surgery (until 72\u2009hours postictus) are widely accepted. The aim of the present study is to evaluate the potential benefit of ultra-early surgery (until 24\u2009hours) when compared with early surgery, in those patients who were treated by surgical clipping at the Neurosurgery Department of the Coimbra Hospital and University Centre.<\/jats:p><jats:p>\n          Methods\u2003A 17-year database of consecutive ruptured and surgically treated intracranial aneurysms was analyzed. Outcome was measured by the Glasgow Outcome Scale (GOS). Baseline characteristics were analyzed by the Fisher exact test, the chi-squared and Mann-Whitney tests. Logistic regression was used to assess the impact of good grade according to the World Federation of Neurological Surgeons (WFNS) scale and ultra-early surgery in a good GOS outcome.<\/jats:p><jats:p>\n          Results\u2003343 patients who were submitted to surgical clipping in the first 72\u2009hours post-ictus were included, 165 of whom have undergone ultra-early surgery. Demographics and preoperative characteristics of ultra-early and early surgery patients were similar. Good-grade patients according to the WFNS scale submitted to ultra-early surgery demonstrated an improved GOS at discharge and at 6 months. Poor-grade patients according to the WFNS scale submitted to ultra-early surgery demonstrated an improved GOS at discharge.<\/jats:p><jats:p>\n          Conclusions\u2003Ultra-early surgery for aneurysmal subarachnoid hemorrhage patients improves outcome mainly on good-grade patients. Efforts should be made on the logistics of emergency departments to consider achieving treatment on this timeframe as a standard of care.<\/jats:p>","DOI":"10.1055\/s-0040-1709202","type":"journal-article","created":{"date-parts":[[2020,5,11]],"date-time":"2020-05-11T23:14:21Z","timestamp":1589238861000},"page":"095-100","source":"Crossref","is-referenced-by-count":0,"title":["Ultra-Early Versus Early Aneurysm Surgery After Subarachnoid Hemorrhage: A Retrospective Outcome Analysis"],"prefix":"10.1055","volume":"39","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4792-1272","authenticated-orcid":false,"given":"Miguel Trigo","family":"Carvalho","sequence":"first","affiliation":[{"name":"Neurosurgery Department, Coimbra Hospital and University Centre, Coimbra, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0951-2278","authenticated-orcid":false,"given":"Ant\u00f3nio","family":"Canotilho Lage","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, University of Coimbra, Coimbra, Portugal"},{"name":"Vila Nova de Gaia\/Espinho Hospital Centre, Vila Nova de Gaia, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6895-1318","authenticated-orcid":false,"given":"Ricardo","family":"Pereira","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, University of Coimbra, Coimbra, Portugal"},{"name":"Neurosurgery Department, Coimbra Hospital and University Centre, Coimbra, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2878-1956","authenticated-orcid":false,"given":"Jorge","family":"Gon\u00e7alves","sequence":"additional","affiliation":[{"name":"Neurosurgery Department, Coimbra Hospital and University Centre, Coimbra, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6408-5857","authenticated-orcid":false,"given":"Ana","family":"Matos","sequence":"additional","affiliation":[{"name":"School of Technology and Management, Polytechnic Institute of Viseu, Viseu, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2142-2849","authenticated-orcid":false,"given":"Carla","family":"Henriques","sequence":"additional","affiliation":[{"name":"School of Technology and Management, Polytechnic Institute of Viseu, Viseu, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5225-6794","authenticated-orcid":false,"given":"Marcos","family":"Barbosa","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, University of Coimbra, Coimbra, Portugal"},{"name":"Neurosurgery Department, Coimbra Hospital and University Centre, Coimbra, Portugal"},{"name":"Centre for Innovative Biomedicine and Biotechnology, University of Coimbra, Portugal"}]}],"member":"194","published-online":{"date-parts":[[2020,4,27]]},"container-title":["Arquivos Brasileiros de Neurocirurgia: Brazilian Neurosurgery"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/s-0040-1709202.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,6,15]],"date-time":"2020-06-15T22:32:37Z","timestamp":1592260357000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.thieme-connect.de\/DOI\/DOI?10.1055\/s-0040-1709202"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,4,27]]},"references-count":0,"journal-issue":{"issue":"02","published-online":{"date-parts":[[2020,6,15]]},"published-print":{"date-parts":[[2020,6]]}},"URL":"https:\/\/doi.org\/10.1055\/s-0040-1709202","relation":{},"ISSN":["0103-5355","2359-5922"],"issn-type":[{"type":"print","value":"0103-5355"},{"type":"electronic","value":"2359-5922"}],"subject":[],"published":{"date-parts":[[2020,4,27]]}}}