{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,5]],"date-time":"2025-08-05T12:33:41Z","timestamp":1754397221465,"version":"3.37.3"},"reference-count":36,"publisher":"Federa\u00e7\u00e3o das Associa\u00e7\u00f5es de Ginecologia e Obstetr\u00edcia","issue":"09","license":[{"start":{"date-parts":[[2020,6,19]],"date-time":"2020-06-19T00:00:00Z","timestamp":1592524800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rev Bras Ginecol Obstet"],"published-print":{"date-parts":[[2020,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Objective\u2003The purpose of the present study was to analyze the influence of chorionicity in the biometric parameters crown-rump length (CRL), birthweight (BW), crown-rump length discordancy (CRLD) and birthweight discordancy (BWD), determine the correlation between these latter two in cases of intertwin discordancy, and to analyze the influence of chronicity in the presence of these discordancies with clinical relevance (&gt; 10% and\u2009&gt;\u200915%, respectively).<\/jats:p><jats:p>Methods\u2003The present study was a retrospective study based on the twin pregnancy database of the Centro Hospitalar S. Jo\u00e3o (2010\u20132015), including 486 fetuses among 66 monochorionic (MC) and 177 dichorionic gestations (DC). The inclusion criteria were multiple pregnancies with 2 fetuses and healthy twin gestations. The exclusion criteria were trichorionic gestations and pregnancies with inconclusive chorionicity, multiple pregnancy with \u2265 3 fetuses and pathological twin gestations.<\/jats:p><jats:p>Results\u2003No statistically significant difference was found in BW (p\u2009=\u20090.09) and in its discordancy (p\u2009=\u20090.06) nor in CRL (p\u2009=\u20090.48) and its discordancy (p\u2009=\u20090.74) between MCs and DCs. Crown-rump length discordancy and birthweight discordancy were correlated by the regression line \u201cBWD\u2009=\u20090.8864 x CRLD\u2009+\u20090.0743,\u201d with r2 \u2009=\u20090.1599. Crown-rump length discordancy\u2009&gt;\u200910% was found in 7.58% of monochorionic and in 13.56% of dichorionic twins. Birthweight discordancy\u2009&gt;\u200915% was detected in 16.67% of monochorionic and in 31.64% of dichorionic twins.<\/jats:p><jats:p>Conclusion\u2003No statistically significant influence of chorionicity was identified in both birthweight and birthweight discordancy, as in crown-rump length and crown-rump length discordancy. Birthweight discordancy was correlated to crown-rump length discordancy in 20% of cases.<\/jats:p>","DOI":"10.1055\/s-0040-1712128","type":"journal-article","created":{"date-parts":[[2020,6,19]],"date-time":"2020-06-19T23:26:58Z","timestamp":1592609218000},"page":"529-534","source":"Crossref","is-referenced-by-count":4,"title":["Twin Pregnancies, Crown-rump Length and Birthweight Discordancy: The Influence of Chorionicity"],"prefix":"10.61622","volume":"42","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1201-1578","authenticated-orcid":false,"given":"Joana Sousa","family":"Nunes","sequence":"additional","affiliation":[{"name":"Obstetrics & Gynecology Department, Senhora da Oliveira Hospital, Guimar\u00e3es, Portugal"},{"name":"Obstetrics & Gynecology Department, Faculty of Medicine, Minho University, Braga, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7200-1705","authenticated-orcid":false,"given":"M\u00e1rio","family":"Sousa","sequence":"additional","affiliation":[{"name":"Laboratory of Cell Biology, Microscopy Department, Porto Hospital Centre, Institute of Biomedical Sciences Abel Salazar, Porto University, Porto, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2806-3471","authenticated-orcid":false,"given":"Nuno","family":"Montenegro","sequence":"additional","affiliation":[{"name":"Obstetrics & Gynecology Department, S\u00e3o Jo\u00e3o Hospital & University Centre, Porto, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1276-1942","authenticated-orcid":false,"given":"Alexandra","family":"Matias","sequence":"additional","affiliation":[{"name":"Obstetrics & Gynecology Department, S\u00e3o Jo\u00e3o Hospital & University Centre, Porto, Portugal"}]}],"member":"47794","published-online":{"date-parts":[[2020,6,19]]},"reference":[{"issue":"01","key":"ref1","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1111\/1754-9485.12268","article-title":"Double trouble: the importance of reporting chorionicity and amnionicity in twin pregnancy ultrasound reports","volume":"59","author":"S Constantine","year":"2015","journal-title":"J Med Imaging Radiat Oncol"},{"issue":"04","key":"ref2","doi-asserted-by":"crossref","first-page":"368","DOI":"10.1017\/thg.2015.43","article-title":"The influence of chorion type on health measures at birth and dental development in Australian and Dutch twins: a comparative study","volume":"18","author":"S Mihailidis","year":"2015","journal-title":"Twin Res Hum Genet"},{"issue":"04","key":"ref3","doi-asserted-by":"crossref","first-page":"827","DOI":"10.1017\/thg.2013.32","article-title":"The precise timing of embryo splitting for monozygotic dichorionic diamniotic twins: when does embryo splitting for monozygotic dichorionic diamniotic twins occur? Evidence for splitting at the morula\/blastocyst stage from studies of in vitro fertilization","volume":"16","author":"K Kyono","year":"2013","journal-title":"Twin Res Hum Genet"},{"issue":"03","key":"ref4","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1111\/j.1600-0412.2011.01288.x","article-title":"Prospective risk of fetal death in uncomplicated monochorionic twins","volume":"91","author":"N Farah","year":"2012","journal-title":"Acta Obstet Gynecol Scand"},{"issue":"01","key":"ref5","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1002\/uog.10057","article-title":"Influence of chorionicity on perinatal outcome in a large cohort of Danish twin pregnancies","volume":"39","author":"A Oldenburg","year":"2012","journal-title":"Ultrasound Obstet Gynecol"},{"issue":"09","key":"ref6","doi-asserted-by":"crossref","first-page":"2549","DOI":"10.1093\/humrep\/der213","article-title":"Stillbirth and neonatal mortality in monochorionic and dichorionic twins: a population-based study","volume":"26","author":"S V Glinianaia","year":"2011","journal-title":"Hum Reprod"},{"issue":"06","key":"ref7","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1375\/twin.13.6.609","article-title":"The frequency and clinical significance of twin gestations according to zygosity and chorionicity","volume":"13","author":"K A Lee","year":"2010","journal-title":"Twin Res Hum Genet"},{"issue":"05","key":"ref8","doi-asserted-by":"crossref","first-page":"494.e1","DOI":"10.1016\/j.ajog.2009.01.048","article-title":"The pregnancy and long-term neurodevelopmental outcome of monochorionic diamniotic twin gestations: a multicenter prospective cohort study from the first trimester onward","volume":"200","author":"E Ortibus","year":"2009","journal-title":"Am J Obstet Gynecol"},{"issue":"03","key":"ref9","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1046\/j.1469-0705.2000.00072.x","article-title":"Is less intensive fetal surveillance of dichorionic twin gestations justified?","volume":"15","author":"D M Sherer","year":"2000","journal-title":"Ultrasound Obstet Gynecol"},{"key":"ref10","doi-asserted-by":"publisher","first-page":"757","DOI":"10.1016\/j.ajog.2005.01.024","article-title":"Is zygosity or chorionicity the main determinant of fetal outcome in twin pregnancies?","volume":"193","author":"S G Carroll","year":"2005","journal-title":"Am J Obstet Gynecol"},{"issue":"07","key":"ref11","doi-asserted-by":"crossref","first-page":"890","DOI":"10.1002\/uog.6140","article-title":"Intrauterine growth in multiple pregnancies in relation to fetal number, chorionicity and gestational age","volume":"32","author":"A T Papageorghiou","year":"2008","journal-title":"Ultrasound Obstet Gynecol"},{"issue":"03","key":"ref12","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1053\/j.semperi.2008.02.009","article-title":"Growth abnormalities and multiple gestations","volume":"32","author":"J Cleary-Goldman","year":"2008","journal-title":"Semin Perinatol"},{"issue":"01","key":"ref13","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1375\/twin.11.1.63","article-title":"Effects of chorion type on genetic and environmental influences on height, weight, and body mass index in South Korean young twins","volume":"11","author":"Y M Hur","year":"2008","journal-title":"Twin Res Hum Genet"},{"issue":"03","key":"ref14","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1038\/sj.jp.7211457","article-title":"Monochorionic monoamniotic twins: neonatal outcome","volume":"26","author":"L Cordero","year":"2006","journal-title":"J Perinatol"},{"issue":"12","key":"ref15","doi-asserted-by":"crossref","first-page":"753","DOI":"10.1038\/sj.jp.7211405","article-title":"Monochorionic diamniotic infants without twin-to-twin transfusion syndrome","volume":"25","author":"L Cordero","year":"2005","journal-title":"J Perinatol"},{"issue":"S 01","key":"ref16","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1111\/j.1365-3016.2005.00611.x","article-title":"Determinants of birthweight and intrauterine growth in liveborn twins","volume":"19","author":"R J Loos","year":"2005","journal-title":"Paediatr Perinat Epidemiol"},{"issue":"03","key":"ref17","doi-asserted-by":"crossref","first-page":"813","DOI":"10.1067\/S0002-9378(03)00658-6","article-title":"Antenatal factors associated with significant birth weight discordancy in twin gestations","volume":"189","author":"V H Gonz\u00e1lez-Quintero","year":"2003","journal-title":"Am J Obstet Gynecol"},{"issue":"05","key":"ref18","first-page":"656","article-title":"Growth pattern of twins of different chorionicity evaluated by sonographic biometry","volume":"95","author":"M Senoo","year":"2000","journal-title":"Obstet Gynecol"},{"issue":"04","key":"ref19","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1002\/pd.4318","article-title":"Reference charts for fetal biometric parameters in twin pregnancies according to chorionicity","volume":"34","author":"E Araujo J\u00fanior","year":"2014","journal-title":"Prenat Diagn"},{"issue":"01","key":"ref20","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1016\/j.ajog.2003.07.025","article-title":"Neonatal mortality rates among growth-discordant twins, classified according to the birth weight of the smaller twin","volume":"190","author":"I Blickstein","year":"2004","journal-title":"Am J Obstet Gynecol"},{"issue":"06","key":"ref21","doi-asserted-by":"crossref","first-page":"587.e1","DOI":"10.1016\/j.ajog.2007.05.009","article-title":"Placental sharing, birthweight discordancy, and vascular anastomoses in monochorionic diamniotic twin placentas","volume":"197","author":"L Lewi","year":"2007","journal-title":"Am J Obstet Gynecol"},{"issue":"01","key":"ref22","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1515\/jpm.2010.124","article-title":"Abdominal circumference ratio for the diagnosis of intertwin birth weight discordancy","volume":"39","author":"T Simoes","year":"2011","journal-title":"J Perinat Med"},{"issue":"02","key":"ref23","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1515\/JPM.2006.028","article-title":"The Northwestern twin chorionicity study: testing the 'placental crowding' hypothesis","volume":"34","author":"I Blickstein","year":"2006","journal-title":"J Perinat Med"},{"issue":"06","key":"ref24","doi-asserted-by":"crossref","first-page":"671","DOI":"10.1515\/jpm.2010.104","article-title":"The source of error in the estimation of intertwin birth weight discordancy","volume":"38","author":"M A Reberdao","year":"2010","journal-title":"J Perinat Med"},{"issue":"01","key":"ref25","first-page":"11","article-title":"Characterization of the growth-discordant twin","volume":"70","author":"I Blickstein","year":"1987","journal-title":"Obstet Gynecol"},{"issue":"06","key":"ref26","first-page":"986","article-title":"Adaptive growth restriction as a pattern of birth weight discordancy in twin gestations","volume":"96","author":"I Blickstein","year":"2000","journal-title":"Obstet Gynecol"},{"issue":"01","key":"ref27","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1016\/j.placenta.2008.09.016","article-title":"Placental characteristics of monoamniotic twin pregnancies in relation to perinatal outcome","volume":"30","author":"K E Hack","year":"2009","journal-title":"Placenta"},{"issue":"03","key":"ref28","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1016\/j.placenta.2011.12.004","article-title":"Placental characteristics in growth-discordant monochorionic twins: a matched case-control study","volume":"33","author":"E Lopriore","year":"2012","journal-title":"Placenta"},{"issue":"02","key":"ref29","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1375\/twin.11.2.219","article-title":"Perinatal outcome and change in body mass index in mothers of dichorionic twins: a longitudinal cohort study","volume":"11","author":"T Sim\u00f5es","year":"2008","journal-title":"Twin Res Hum Genet"},{"issue":"06","key":"ref30","doi-asserted-by":"crossref","first-page":"526","DOI":"10.1375\/136905203322686536","article-title":"Birthweight discordancy in multiple pregnancy","volume":"6","author":"I Blickstein","year":"2003","journal-title":"Twin Res"},{"issue":"04","key":"ref31","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1017\/thg.2012.26","article-title":"Neonatal morbidity in growth-discordant monochorionic twins: comparison between the larger and the smaller twin","volume":"15","author":"E Lopriore","year":"2012","journal-title":"Twin Res Hum Genet"},{"issue":"17","key":"ref32","doi-asserted-by":"crossref","first-page":"2883","DOI":"10.3109\/14767058.2015.1107901","article-title":"Intertwin crown-rump length discordancy in the prediction of fetal anomalies, fetal loss and adverse perinatal outcome","volume":"29","author":"M Grande","year":"2016","journal-title":"J Matern Fetal Neonatal Med"},{"issue":"08","key":"ref33","doi-asserted-by":"crossref","first-page":"748","DOI":"10.1002\/pd.4359","article-title":"The association of crown-rump length discrepancy with birthweight discordancy in spontaneous versus assisted conception dichorionic twins","volume":"34","author":"I Ben-Ami","year":"2014","journal-title":"Prenat Diagn"},{"issue":"02","key":"ref34","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1002\/uog.13335","article-title":"Crown-rump length discordancy and adverse perinatal outcome in twin pregnancies: systematic review and meta-analysis","volume":"44","author":"F D'Antonio","year":"2014","journal-title":"Ultrasound Obstet Gynecol"},{"key":"ref35","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/j.bpobgyn.2016.09.004","article-title":"Antenatal fetal surveillance in multiple pregnancies","volume":"38","author":"D Oepkes","year":"2017","journal-title":"Best Pract Res Clin Obstet Gynaecol"},{"issue":"09","key":"ref36","doi-asserted-by":"crossref","first-page":"704","DOI":"10.1038\/jp.2016.82","article-title":"Optimal threshold for birth weight discordancy: Does knowledge of chorionicity matter?","volume":"36","author":"S Jahanfar","year":"2016","journal-title":"J Perinatol"}],"container-title":["Revista Brasileira de Ginecologia e Obstetr\u00edcia \/ RBGO Gynecology and Obstetrics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journalrbgo.org\/article\/twin-pregnancies-crown-rump-length-and-birthweight-discordancy-the-influence-of-chorionicity\/","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.thieme-connect.de\/products\/ejournals\/pdf\/10.1055\/s-0040-1712128.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,7,18]],"date-time":"2024-07-18T20:52:14Z","timestamp":1721335934000},"score":1,"resource":{"primary":{"URL":"https:\/\/journalrbgo.org\/article\/twin-pregnancies-crown-rump-length-and-birthweight-discordancy-the-influence-of-chorionicity\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,6,19]]},"references-count":36,"journal-issue":{"issue":"09","published-online":{"date-parts":[[2020,9,29]]},"published-print":{"date-parts":[[2020,9]]}},"URL":"https:\/\/doi.org\/10.1055\/s-0040-1712128","archive":["Portico","CLOCKSS"],"relation":{},"ISSN":["0100-7203","1806-9339"],"issn-type":[{"type":"print","value":"0100-7203"},{"type":"electronic","value":"1806-9339"}],"subject":[],"published":{"date-parts":[[2020,6,19]]}}}