{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T12:57:55Z","timestamp":1740142675001,"version":"3.37.3"},"reference-count":47,"publisher":"Federa\u00e7\u00e3o das Associa\u00e7\u00f5es de Ginecologia e Obstetr\u00edcia","issue":"04","license":[{"start":{"date-parts":[[2021,5,12]],"date-time":"2021-05-12T00:00:00Z","timestamp":1620777600000},"content-version":"vor","delay-in-days":41,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rev Bras Ginecol Obstet"],"published-print":{"date-parts":[[2021,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Preterm birth (PTB) is a major obstetric problem associated with high rates of neonatal morbidity and mortality. The prevalence of PTB has not changed in the last decade; thus, the establishment of a screening test and effective treatment are warranted. Transvaginal ultrasound measurement of the cervical length (TUCL) has been proposed as an effective method to screen pregnant women at a higher risk of experiencing PTB.<\/jats:p><jats:p>\n          Objective\u2003To evaluate the applicability and usefulness of second-trimester TUCL to predict PTB in a cohort of Portuguese pregnant women.<\/jats:p><jats:p>\n          Methods\u2003Retrospective cross-sectional cohort study including all singleton pregnant women who performed their second-trimester ultrasound (between weeks 18 and 22\u2009+\u20096 days) from January 2013 to October 2017 at Centro Hospitalar Universit\u00e1rio S\u00e3o Jo\u00e3o.<\/jats:p><jats:p>\n          Results\u2003Our cohort included 4,481 women. The prevalence of spontaneous PTB was of 4.0%, with 0.7% occurring before the 34th week of gestation. The mean TUCL was of 33.8\u2009mm, and percentiles 3, 5 and 10 corresponded to TUCLs of 25.0\u2009mm, 27.0\u2009mm and 29.0\u2009mm respectively. The multiple logistic regression analysis, including maternal age, previous PTB and cervical surgery showed a significant negative association between TUCL and PTB, with an odds ratio (OR) of 0.92 (95% confidence interval [95%CI]: 0.90\u20130.95; p\u2009&lt;\u20090.001). The use of a TUCL of 20\u2009mm is the best cut-off, when compared with the 25-mm cut-off, improving the prediction of risk.<\/jats:p><jats:p>\n          Conclusion\u2003The present study showed an inverse association between TUCL and PTB, and that the inclusion of other risk factors like maternal age, previous PTB and cervical surgery can improve the screening algorithm. Furthermore, it emphasizes that the TUCL cut-off that defines short cervix can differ according to the population.<\/jats:p>","DOI":"10.1055\/s-0041-1726053","type":"journal-article","created":{"date-parts":[[2021,5,12]],"date-time":"2021-05-12T22:51:25Z","timestamp":1620859885000},"page":"264-274","source":"Crossref","is-referenced-by-count":2,"title":["The Impact of Routine Transvaginal Ultrasound Measurement of the Cervical Length on the Prediction of Preterm Birth: A Retrospective Study in a Tertiary Hospital"],"prefix":"10.61622","volume":"43","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5559-6137","authenticated-orcid":false,"given":"Joana Patricia Rodrigues F\u00e9lix Peixoto de","family":"Almeida","sequence":"additional","affiliation":[{"name":"Department of Gynecology and Obstetrics, Faculdade de Medicina, Hospital Pedro Hispano, Universidade do Porto, Porto, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0646-7667","authenticated-orcid":false,"given":"Carla Maria Magno","family":"Bartosch","sequence":"additional","affiliation":[{"name":"Department of Pathology, Instituto Portugu\u00eas de Oncologia do Porto, Porto, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2967-5365","authenticated-orcid":false,"given":"Alexandra Matias Pereira Cunha Coelho","family":"Macedo","sequence":"additional","affiliation":[{"name":"Department of Gynecology and Obstetrics, Faculdade de Medicina, Centro Hospitalar Universit\u00e1rio S\u00e3o, Universidade do Porto, Porto, Portugal"}]}],"member":"47794","published-online":{"date-parts":[[2021,5,12]]},"reference":[{"issue":"02","key":"ref1","doi-asserted-by":"publisher","first-page":"126","DOI":"10.1016\/j.siny.2017.11.007","article-title":"Screening for spontaneous preterm birth and resultant therapies to reduce neonatal morbidity and mortality: A review","volume":"23","author":"A V Glover","year":"2018","journal-title":"Semin Fetal Neonatal 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