{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T15:44:40Z","timestamp":1792165480144,"version":"4.4.0"},"reference-count":33,"publisher":"Massachusetts Medical Society","issue":"10","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["NEJM Evidence"],"published-print":{"date-parts":[[2025,9,23]]},"DOI":"10.1056\/evidoa2500095","type":"journal-article","created":{"date-parts":[[2025,9,23]],"date-time":"2025-09-23T13:30:18Z","timestamp":1758634218000},"source":"Crossref","is-referenced-by-count":22,"title":["Cendakimab in Adults and Adolescents with Eosinophilic Esophagitis"],"prefix":"10.1056","volume":"4","author":[{"given":"Evan S.","family":"Dellon","sequence":"first","affiliation":[{"name":"Center for Esophageal Diseases and Swallowing, Division of Gastroenterology and Hepatology, University of North Carolina School of Medicine, Chapel Hill"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christina M.","family":"Charriez","sequence":"additional","affiliation":[{"name":"Bristol Myers Squibb, Princeton, NJ"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sandra","family":"Zhang","sequence":"additional","affiliation":[{"name":"Bristol Myers Squibb, Princeton, NJ"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gary W.","family":"Falk","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology and Hepatology, Perelman School of Medicine, University of Pennsylvania, Philadelphia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Salvatore","family":"Oliva","sequence":"additional","affiliation":[{"name":"Pediatric Gastroenterology and Liver Unit, Maternal and Child Health Department, Sapienza University of Rome, University Hospital Umberto I, Rome, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher","family":"Ma","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology and Hepatology, Departments of Medicine and Community Health Sciences, University of Calgary, Calgary, AB, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jesse","family":"Siffledeen","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology, Department of Medicine, University of Alberta, Edmonton"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shauna","family":"Schroeder","sequence":"additional","affiliation":[{"name":"Division of Pediatric Gastroenterology and Hepatology, Phoenix Children\u2019s Hospital, Phoenix, AZ"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hamish","family":"Philpott","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Lyell McEwin Hospital, Northern Adelaide Local Health Network, University of Adelaide, Adelaide, SA, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tim","family":"Vanuytsel","sequence":"additional","affiliation":[{"name":"University Hospital Leuven, Leuven, Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasuhiko","family":"Abe","sequence":"additional","affiliation":[{"name":"Division of Endoscopy, Yamagata University Hospital, Yamagata, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kexuan","family":"Li","sequence":"additional","affiliation":[{"name":"Bristol Myers Squibb, Princeton, NJ"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carla L.","family":"Zema","sequence":"additional","affiliation":[{"name":"Bristol Myers Squibb, Princeton, NJ"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ashwini","family":"Venkatasamy","sequence":"additional","affiliation":[{"name":"Bristol Myers Squibb, Princeton, NJ"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anusha K.","family":"Yeshokumar","sequence":"additional","affiliation":[{"name":"Bristol Myers Squibb, Princeton, NJ"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Young S.","family":"Oh","sequence":"additional","affiliation":[{"name":"Bristol Myers Squibb, Princeton, NJ"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alain","family":"Schoepfer","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology, Centre Hospitalier Universitaire Vaudois and University of Lausanne, Lausanne, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"150","reference":[{"key":"e_1_3_5_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.anai.2022.10.004"},{"key":"e_1_3_5_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.mcna.2018.08.009"},{"key":"e_1_3_5_4_2","doi-asserted-by":"publisher","DOI":"10.1177\/2050640616689525"},{"key":"e_1_3_5_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2023.06.005"},{"key":"e_1_3_5_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2024.09.031"},{"key":"e_1_3_5_7_2","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2017.06.065"},{"key":"e_1_3_5_8_2","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2018.10.051"},{"key":"e_1_3_5_9_2","doi-asserted-by":"publisher","DOI":"10.1038\/nrgastro.2017.56"},{"key":"e_1_3_5_10_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2205982"},{"key":"e_1_3_5_11_2","doi-asserted-by":"publisher","DOI":"10.1007\/s12325-017-0525-8"},{"key":"e_1_3_5_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.gastha.2022.05.004"},{"key":"e_1_3_5_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cct.2024.107708"},{"key":"e_1_3_5_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2020.03.036"},{"key":"e_1_3_5_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2020.03.045"},{"key":"e_1_3_5_16_2","doi-asserted-by":"publisher","DOI":"10.1136\/gutjnl-2011-301817"},{"key":"e_1_3_5_17_2","doi-asserted-by":"publisher","DOI":"10.1111\/dote.12470"},{"key":"e_1_3_5_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2019.01.030"},{"key":"e_1_3_5_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2017.09.046"},{"key":"e_1_3_5_20_2","unstructured":"U.S. Food and Drug Administration. Guidance for industry: patient-reported outcome measures: use in medical product development to support labeling claims. December 2009 (https:\/\/www.fda.gov\/media\/77832\/download)."},{"key":"e_1_3_5_21_2","unstructured":"U.S. Food and Drug Administration. Eosinophilic esophagitis: developing drugs for treatment. September 2020 (https:\/\/www.fda.gov\/media\/120089\/download)."},{"key":"e_1_3_5_22_2","unstructured":"U.S. Food and Drug Administration. Guidance document: patient-focused drug development: incorporating clinical outcome assessments into endpoints for regulatory decision-making. April 2023 (https:\/\/www.fda.gov\/regulatory-information\/search-fda-guidance-documents\/patient-focused-drug-development-incorporating-clinical-outcome-assessments-endpoints-regulatory)."},{"key":"e_1_3_5_23_2","unstructured":"SAS Institute Inc. SAS\/STAT 14.1 User\u2019s Guide. The MI Procedure. Cary NC. 2015."},{"key":"e_1_3_5_24_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.anai.2022.10.026"},{"key":"e_1_3_5_25_2","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.1000471"},{"key":"e_1_3_5_26_2","doi-asserted-by":"publisher","DOI":"10.3390\/cells12202473"},{"key":"e_1_3_5_27_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.gtc.2014.02.006"},{"key":"e_1_3_5_28_2","doi-asserted-by":"publisher","DOI":"10.14309\/ajg.0000000000002094"},{"key":"e_1_3_5_29_2","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2023.09.004"},{"key":"e_1_3_5_30_2","unstructured":"Joszt L. FDA approves dupilumab to treat EoE for children under 12 years. American Journal of Managed Care. January 25 2024 (https:\/\/www.ajmc.com\/view\/fda-approves-dupilumab-to-treat-eoe-for-children-under-12-years)."},{"key":"e_1_3_5_31_2","doi-asserted-by":"publisher","DOI":"10.1111\/all.14151"},{"key":"e_1_3_5_32_2","doi-asserted-by":"publisher","DOI":"10.1136\/gutjnl-2023-330337"},{"key":"e_1_3_5_33_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2021.04.022"},{"key":"e_1_3_5_34_2","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2019.09.052"}],"container-title":["NEJM Evidence"],"original-title":[],"language":"en","deposited":{"date-parts":[[2025,9,23]],"date-time":"2025-09-23T20:55:59Z","timestamp":1758660959000},"score":1,"resource":{"primary":{"URL":"https:\/\/evidence.nejm.org\/doi\/10.1056\/EVIDoa2500095"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,9,23]]},"references-count":33,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2025,9,23]]}},"alternative-id":["10.1056\/EVIDoa2500095"],"URL":"https:\/\/doi.org\/10.1056\/evidoa2500095","relation":{},"ISSN":["2766-5526"],"issn-type":[{"value":"2766-5526","type":"print"}],"subject":[],"published":{"date-parts":[[2025,9,23]]}}}