{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T17:00:24Z","timestamp":1790960424044,"version":"4.1.0"},"reference-count":33,"publisher":"Massachusetts Medical Society","issue":"7","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["NEJM Evidence"],"published-print":{"date-parts":[[2026,6,23]]},"DOI":"10.1056\/evidoa2600112","type":"journal-article","created":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T15:30:15Z","timestamp":1780500615000},"source":"Crossref","is-referenced-by-count":6,"title":["Secukinumab for Giant Cell Arteritis"],"prefix":"10.1056","volume":"5","author":[{"given":"John H.","family":"Stone","sequence":"first","affiliation":[{"name":"Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nils","family":"Venhoff","sequence":"additional","affiliation":[{"name":"Department of Rheumatology and Clinical Immunology, Medical Center, University of Freiburg, Freiburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frank","family":"Buttgereit","sequence":"additional","affiliation":[{"name":"Department of Rheumatology and Clinical Immunology, Charit\u00e9 Universit\u00e4tsmedizin Berlin, Berlin, Germany"},{"name":"Deutsches Rheumaforschungszentrum, ein Institut der Leibniz Gemeinschaft, Berlin, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian","family":"Dejaco","sequence":"additional","affiliation":[{"name":"Department of Rheumatology, Hospital of Brunico, S\u00fcdtiroler Sanit\u00e4tsbetrieb \u2014 Azienda Sanitaria dell\u2019Alto Adige (SABES-ASAA), Teaching Hospital of the Paracelsus University, Brunico, Italy"},{"name":"Department of Rheumatology and Immunology, Medical University of Graz, Graz, Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wolfgang A.","family":"Schmidt","sequence":"additional","affiliation":[{"name":"Immanuel Krankenhaus Berlin, Medical Center for Rheumatology Berlin-Buch, Berlin, Germany"},{"name":"Rheumatology, Waldfriede Hospital, Berlin, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert","family":"Spiera","sequence":"additional","affiliation":[{"name":"Department of Medicine, Hospital for Special Surgery, New York, NY, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ricardo","family":"Blanco","sequence":"additional","affiliation":[{"name":"Servicio de Reumatolog\u00eda, Hospital Universitario Marqu\u00e9s de Valdecilla, IDIVAL, Immunopathology Group, Medicine and Psychiatry Department, University of Cantabria, Santander, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"Rubbert-Roth","sequence":"additional","affiliation":[{"name":"Department of Rheumatology, University of Zurich, Zurich, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian","family":"Von Frenckell","sequence":"additional","affiliation":[{"name":"Service de Rhumatologie, CHU de Li\u00e8ge, Li\u00e8ge, Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel","family":"Blockmans","sequence":"additional","affiliation":[{"name":"Department of General Internal Medicine, University Hospitals Leuven, Leuven, Belgium"},{"name":"Department of Microbiology, Immunology, and Transplantation, KU Leuven, Leuven, Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Benjamin","family":"Terrier","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, National Referral Center for Rare Systemic Autoimmune Diseases, H\u00f4pital Cochin, Assistance Publique-H\u00f4pitaux de Paris, Paris, France"},{"name":"Universit\u00e9 Paris Cit\u00e9, Paris, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gerald","family":"Tracey","sequence":"additional","affiliation":[{"name":"Paradise Arthritis and Rheumatology, Gold Coast, QLD, Australia"},{"name":"Griffith University, Brisbane, QLD, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ellen Margrethe","family":"Hauge","sequence":"additional","affiliation":[{"name":"Department of Rheumatology, Aarhus University Hospital, Aarhus, Denmark"},{"name":"Department of Clinical Medicine, Aarhus University, Aarhus, Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Monica Pastoral","family":"Keyport","sequence":"additional","affiliation":[{"name":"Novartis Pharmaceuticals Corporation, East Hanover, NJ, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer","family":"Ng","sequence":"additional","affiliation":[{"name":"Novartis Pharmaceuticals Corporation, East Hanover, NJ, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Renuka","family":"Hiremath","sequence":"additional","affiliation":[{"name":"Novartis Healthcare Pvt Ltd, Hyderabad, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rong","family":"Fu","sequence":"additional","affiliation":[{"name":"China Novartis Institutes for Biomedical Research, Shanghai, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"GaEun","family":"Cho","sequence":"additional","affiliation":[{"name":"Novartis Pharmaceuticals Corporation, East Hanover, NJ, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gerald","family":"Bacher","sequence":"additional","affiliation":[{"name":"Novartis Pharma AG, Basel, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jens","family":"Thiel","sequence":"additional","affiliation":[{"name":"Department of Rheumatology and Clinical Immunology, Medical Center, University of Freiburg, Freiburg, Germany"},{"name":"Department of Rheumatology and Immunology, Medical University of Graz, Graz, Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meryl H.","family":"Mendelson","sequence":"additional","affiliation":[{"name":"Novartis Pharmaceuticals Corporation, East Hanover, NJ, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"150","reference":[{"key":"e_1_3_5_2_2","doi-asserted-by":"publisher","DOI":"10.55563\/clinexprheumatol\/xc46ld"},{"key":"e_1_3_5_3_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12877-019-1225-9"},{"key":"e_1_3_5_4_2","doi-asserted-by":"publisher","DOI":"10.1002\/art.24459"},{"key":"e_1_3_5_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(08)61077-6"},{"key":"e_1_3_5_6_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41433-019-0608-7"},{"key":"e_1_3_5_7_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2016.5444"},{"key":"e_1_3_5_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.autrev.2023.103415"},{"key":"e_1_3_5_9_2","doi-asserted-by":"publisher","DOI":"10.1002\/art.11388"},{"key":"e_1_3_5_10_2","doi-asserted-by":"publisher","DOI":"10.1007\/s40744-019-00180-9"},{"key":"e_1_3_5_11_2","doi-asserted-by":"publisher","DOI":"10.1002\/acr.23901"},{"key":"e_1_3_5_12_2","doi-asserted-by":"publisher","DOI":"10.1007\/s40744-025-00778-2"},{"key":"e_1_3_5_13_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMc1711031"},{"key":"e_1_3_5_14_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2413449"},{"key":"e_1_3_5_15_2","volume-title":"RINVOQ [package insert]","author":"AbbVie","unstructured":"AbbVie. RINVOQ [package insert]. North Chicago, IL: AbbVie Inc., 2025."},{"key":"e_1_3_5_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.autrev.2024.103580"},{"key":"e_1_3_5_17_2","doi-asserted-by":"publisher","DOI":"10.1002\/art.43098"},{"key":"e_1_3_5_18_2","doi-asserted-by":"publisher","DOI":"10.3899\/jrheum.2024-0612"},{"key":"e_1_3_5_19_2","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2023.1199059"},{"key":"e_1_3_5_20_2","doi-asserted-by":"publisher","DOI":"10.1007\/s40744-025-00754-w"},{"key":"e_1_3_5_21_2","doi-asserted-by":"publisher","DOI":"10.1007\/s13555-024-01122-2"},{"key":"e_1_3_5_22_2","doi-asserted-by":"publisher","DOI":"10.1016\/S2665-9913(23)00101-7"},{"key":"e_1_3_5_23_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.semarthrit.2022.152010"},{"key":"e_1_3_5_24_2","doi-asserted-by":"publisher","DOI":"10.1097\/00005650-199206000-00002"},{"key":"e_1_3_5_25_2","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.1993.11.3.570"},{"key":"e_1_3_5_26_2","doi-asserted-by":"publisher","DOI":"10.1016\/s0885-3924(96)00274-6"},{"key":"e_1_3_5_27_2","doi-asserted-by":"publisher","DOI":"10.1214\/12-AOAS583"},{"key":"e_1_3_5_28_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1541-0420.2008.01177.x"},{"key":"e_1_3_5_29_2","article-title":"Phase 3 trial of secukinumab in polymyalgia rheumatica","year":"2026","unstructured":"Stone JH, Buttgereit F, Saraux A, et al. Phase 3 trial of secukinumab in polymyalgia rheumatica. N Engl J Med 2026:NEJMoa2602567.","journal-title":"N Engl J Med"},{"key":"e_1_3_5_30_2","doi-asserted-by":"publisher","DOI":"10.1136\/annrheumdis-2021-220347"},{"key":"e_1_3_5_31_2","doi-asserted-by":"publisher","DOI":"10.1177\/17455057221147385"},{"key":"e_1_3_5_32_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbspin.2022.105494"},{"key":"e_1_3_5_33_2","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/keaf689"},{"key":"e_1_3_5_34_2","doi-asserted-by":"publisher","DOI":"10.1126\/scisignal.2001077"}],"container-title":["NEJM Evidence"],"original-title":[],"language":"en","deposited":{"date-parts":[[2026,6,23]],"date-time":"2026-06-23T13:30:30Z","timestamp":1782221430000},"score":1,"resource":{"primary":{"URL":"https:\/\/evidence.nejm.org\/doi\/10.1056\/EVIDoa2600112"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,6,23]]},"references-count":33,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2026,6,23]]}},"alternative-id":["10.1056\/EVIDoa2600112"],"URL":"https:\/\/doi.org\/10.1056\/evidoa2600112","relation":{},"ISSN":["2766-5526"],"issn-type":[{"value":"2766-5526","type":"print"}],"subject":[],"published":{"date-parts":[[2026,6,23]]}}}