{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T10:28:51Z","timestamp":1772965731120,"version":"3.50.1"},"reference-count":27,"publisher":"Massachusetts Medical Society","issue":"7","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["N Engl J Med"],"published-print":{"date-parts":[[1969,8,14]]},"DOI":"10.1056\/nejm196908142810702","type":"journal-article","created":{"date-parts":[[2010,7,28]],"date-time":"2010-07-28T20:09:16Z","timestamp":1280347756000},"page":"338-343","source":"Crossref","is-referenced-by-count":66,"title":["Beta-Galactosidase Deficiency in the Hurler Syndrome"],"prefix":"10.1056","volume":"281","author":[{"given":"Monica","family":"MacBrinn","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shintaro","family":"Okada","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marjorie","family":"Woollacott","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vimal","family":"Patel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mae Wan","family":"Ho","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A. L.","family":"Tappel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J. S.","family":"O'Brien","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"150","reference":[{"key":"r001","unstructured":"McKusick, V. A. Heritable Disorders of Connective Tissue. Third edition. St. Louis: Mosby, 1966. pp. 325\u2013390."},{"key":"r002","doi-asserted-by":"publisher","DOI":"10.1097\/00005072-196504000-00012"},{"key":"r003","doi-asserted-by":"publisher","DOI":"10.1007\/BF02641015"},{"key":"r004","first-page":"1281","volume":"259","author":"Van Hoof","year":"1964","journal-title":"Compt. rend. Acad. d. Sc."},{"key":"r005","first-page":"1578","volume":"15","author":"Lagunoff","year":"1966","journal-title":"Lab. Investigation"},{"key":"r006","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.60.2.699"},{"key":"r007","doi-asserted-by":"publisher","DOI":"10.1126\/science.160.3831.1002"},{"key":"r008","doi-asserted-by":"publisher","DOI":"10.1126\/science.163.3870.946"},{"key":"r009","doi-asserted-by":"publisher","DOI":"10.1016\/S0926-6593(66)80014-0"},{"key":"r010","unstructured":"Tappel, A. L. Lysosomes. In Comprehensive Biochemistry. Section 5. Chemical biology. Vol. 23. Cytochemistry. Edited by M. Florkin and E. H. Stotz. New York: Elsevier Pub. Co., 1968. pp. 77\u201398."},{"key":"r011","doi-asserted-by":"publisher","DOI":"10.1126\/science.159.3822.1471"},{"key":"r012","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9673(01)91257-9"},{"key":"r013","doi-asserted-by":"publisher","DOI":"10.1016\/0003-2697(65)90238-1"},{"key":"r014","doi-asserted-by":"publisher","DOI":"10.1016\/0009-8981(68)90375-6"},{"key":"r015","doi-asserted-by":"publisher","DOI":"10.3109\/00365516809160959"},{"key":"r016","doi-asserted-by":"crossref","first-page":"4258","DOI":"10.1016\/S0021-9258(18)93251-5","volume":"243","author":"Jungalwala","year":"1968","journal-title":"J. Biol. Chem."},{"key":"r017","doi-asserted-by":"publisher","DOI":"10.1016\/0003-9861(68)90036-2"},{"key":"r018","first-page":"308","volume":"60","author":"Uzman","year":"1955","journal-title":"Arch. Path."},{"key":"r019","doi-asserted-by":"publisher","DOI":"10.1016\/0926-6534(65)90032-1"},{"key":"r020","doi-asserted-by":"crossref","first-page":"2821","DOI":"10.1016\/S0021-9258(18)97253-4","volume":"240","author":"Lindahl","year":"1965","journal-title":"J. Biol. Chem."},{"key":"r021","doi-asserted-by":"crossref","first-page":"2113","DOI":"10.1016\/S0021-9258(18)96674-3","volume":"241","author":"Lindahl","year":"1966","journal-title":"J. Biol. Chem."},{"key":"r022","doi-asserted-by":"crossref","first-page":"5949","DOI":"10.1016\/S0021-9258(18)96362-3","volume":"241","author":"Rod\u00e9n","year":"1966","journal-title":"J. Biol. Chem."},{"key":"r023","doi-asserted-by":"crossref","first-page":"4652","DOI":"10.1016\/S0021-9258(18)99507-4","volume":"242","author":"Knecht","year":"1967","journal-title":"J. Biol. Chem."},{"key":"r024","doi-asserted-by":"crossref","first-page":"2660","DOI":"10.1016\/S0021-9258(18)93423-X","volume":"243","author":"Bella","year":"1968","journal-title":"J. Biol. Chem."},{"key":"r025","author":"Mahadevan","journal-title":"Arch. Biochem."},{"key":"r026","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1042\/bj0970059","volume":"97","author":"Furth","year":"1965","journal-title":"Biochem. J."},{"key":"r027","doi-asserted-by":"publisher","DOI":"10.1111\/j.1432-1033.1968.tb19570.x"}],"container-title":["New England Journal of Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.nejm.org\/doi\/pdf\/10.1056\/NEJM196908142810702","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,11,2]],"date-time":"2021-11-02T00:41:44Z","timestamp":1635813704000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.nejm.org\/doi\/abs\/10.1056\/NEJM196908142810702"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1969,8,14]]},"references-count":27,"journal-issue":{"issue":"7","published-print":{"date-parts":[[1969,8,14]]}},"alternative-id":["10.1056\/NEJM196908142810702"],"URL":"https:\/\/doi.org\/10.1056\/nejm196908142810702","relation":{},"ISSN":["0028-4793","1533-4406"],"issn-type":[{"value":"0028-4793","type":"print"},{"value":"1533-4406","type":"electronic"}],"subject":[],"published":{"date-parts":[[1969,8,14]]}}}