{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,12]],"date-time":"2026-11-12T18:41:50Z","timestamp":1794508910386,"version":"4.9.1"},"reference-count":30,"publisher":"Massachusetts Medical Society","issue":"24","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["N Engl J Med"],"published-print":{"date-parts":[[1976,6,10]]},"DOI":"10.1056\/nejm197606102942404","type":"journal-article","created":{"date-parts":[[2010,7,28]],"date-time":"2010-07-28T20:43:10Z","timestamp":1280349790000},"page":"1316-1321","source":"Crossref","is-referenced-by-count":656,"title":["Liver Disease in Alpha<sub>1<\/sub>-Antitrypsin Deficiency Detected by Screening of 200,000 Infants"],"prefix":"10.1056","volume":"294","author":[{"given":"Tomas","family":"Sveger","sequence":"first","affiliation":[{"name":"From the departments of Clinical Chemistry and Paediatrics, Malm\u00f6 General Hospital, Malm\u00f6, Sweden (address reprint requests to Dr. Sveger at the Department of Paediatrics, Malm\u00f6 General Hospital, S-214 01 Malm\u00f6, Sweden)."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"150","reference":[{"key":"r001","first-page":"96","volume":"7","author":"Fagerhol","year":"1970","journal-title":"Prog Med Genet"},{"key":"r002","doi-asserted-by":"publisher","DOI":"10.1080\/00365516309051324"},{"key":"r003","first-page":"1","volume":"432","author":"Eriksson","year":"1965","journal-title":"Acta Med Scand"},{"key":"r004","first-page":"934","volume":"73","author":"Sharp","year":"1969","journal-title":"J Lab Clin Med"},{"key":"r005","doi-asserted-by":"publisher","DOI":"10.1080\/21548331.1971.11706032"},{"key":"r006","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM197501232920403"},{"key":"r007","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM197509182931203"},{"key":"r008","doi-asserted-by":"publisher","DOI":"10.1126\/science.181.4094.70"},{"key":"r009","first-page":"118","volume":"1","year":"1975","journal-title":"Lancet"},{"key":"r010","doi-asserted-by":"publisher","DOI":"10.1111\/j.1651-2227.1972.tb15960.x"},{"key":"r011","doi-asserted-by":"crossref","first-page":"837","DOI":"10.1542\/peds.46.6.837","volume":"46","author":"Alper","year":"1970","journal-title":"Pediatrics"},{"key":"r012","doi-asserted-by":"publisher","DOI":"10.1136\/pgmj.50.584.376"},{"key":"r013","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(76)80720-2"},{"key":"r014","unstructured":"Johnson AM: Antiproteases and the liver, The Liver: Normal and abnormal functions. Vol A. Edited by FF Becker. New York, Marcel Dekker Incorporated, 1975, pp 103\u2013128"},{"key":"r015","doi-asserted-by":"publisher","DOI":"10.1111\/j.0954-6820.1974.tb08170.x"},{"key":"r016","first-page":"213","volume":"27","author":"Laurell","year":"1975","journal-title":"Am J Hum Genet"},{"key":"r017","doi-asserted-by":"publisher","DOI":"10.1136\/adc.45.243.702"},{"key":"r018","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1542\/peds.46.1.7","volume":"46","author":"Sterky","year":"1970","journal-title":"Pediatrics"},{"key":"r019","doi-asserted-by":"publisher","DOI":"10.3109\/00365517209080237"},{"key":"r020","doi-asserted-by":"publisher","DOI":"10.3109\/00365517209102748"},{"key":"r021","doi-asserted-by":"publisher","DOI":"10.1016\/0005-2795(73)90135-9"},{"key":"r022","unstructured":"Prince AM: The hepatitis B antigen, The Liver: Normal and abnormal functions. Vol B. Edited by FF Becker. New York, Marcel Dekker Incorporated, 1974, pp 578\u2013581"},{"key":"r023","unstructured":"Sharp H, Freier E: Familial cirrhosis, Pulmonary Emphysema and Proteolysis. Edited by C Mittman. New York, Academic Press, 1972, pp 101\u2013113"},{"key":"r024","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.3.5824.435"},{"key":"r025","doi-asserted-by":"publisher","DOI":"10.1111\/j.1432-1033.1973.tb02932.x"},{"key":"r026","doi-asserted-by":"publisher","DOI":"10.1111\/j.1432-1033.1974.tb03367.x"},{"key":"r027","unstructured":"Gans H: Considerations on the etiology of the hepatic injury observed in patients with homozygous alpha1-antitrypsin deficiency, Pulmonary Emphysema and Proteolysis. Edited by C Mittman. New York, Academic Press, 1972, pp 115\u2013119"},{"key":"r028","doi-asserted-by":"publisher","DOI":"10.1136\/pgmj.50.584.354"},{"key":"r029","first-page":"33a","volume":"24","author":"Cox","year":"1972","journal-title":"Am J Hum Genet"},{"key":"r030","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(74)80385-9"}],"container-title":["New England Journal of Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.nejm.org\/doi\/pdf\/10.1056\/NEJM197606102942404","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,6,2]],"date-time":"2023-06-02T12:07:07Z","timestamp":1685707627000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.nejm.org\/doi\/10.1056\/NEJM197606102942404"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1976,6,10]]},"references-count":30,"journal-issue":{"issue":"24","published-print":{"date-parts":[[1976,6,10]]}},"alternative-id":["10.1056\/NEJM197606102942404"],"URL":"https:\/\/doi.org\/10.1056\/nejm197606102942404","relation":{},"ISSN":["0028-4793","1533-4406"],"issn-type":[{"value":"0028-4793","type":"print"},{"value":"1533-4406","type":"electronic"}],"subject":[],"published":{"date-parts":[[1976,6,10]]}}}