{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,11]],"date-time":"2026-04-11T14:31:07Z","timestamp":1775917867338,"version":"3.50.1"},"reference-count":19,"publisher":"Massachusetts Medical Society","issue":"12","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["N Engl J Med"],"published-print":{"date-parts":[[1984,3,22]]},"DOI":"10.1056\/nejm198403223101202","type":"journal-article","created":{"date-parts":[[2010,7,28]],"date-time":"2010-07-28T21:24:10Z","timestamp":1280352250000},"page":"743-746","source":"Crossref","is-referenced-by-count":76,"title":["The Bronchodilator Effects and Pharmacokinetics of Caffeine in Asthma"],"prefix":"10.1056","volume":"310","author":[{"given":"Allan B.","family":"Becker","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Keith J.","family":"Simons","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Catherine A.","family":"Gillespie","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F. Estelle R.","family":"Simons","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"150","reference":[{"key":"r001","first-page":"1109","volume":"4","author":"Salter","year":"1859","journal-title":"Edinburgh Med J"},{"key":"r002","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(82)90182-9"},{"key":"r003","first-page":"587","volume":"113","author":"Knudson","year":"1976","journal-title":"Am Rev Respir Dis"},{"key":"r004","doi-asserted-by":"publisher","DOI":"10.1002\/jps.2600710507"},{"key":"r005","doi-asserted-by":"crossref","unstructured":"Gibaldi M, Perrier D. Pharmacokinetics. 2nd ed. New York: Marcel Dekker, 1982:1\u201315.","DOI":"10.1201\/b14095"},{"key":"r006","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1016\/S0022-3565(25)09383-8","volume":"18","author":"Macht","year":"1921","journal-title":"J Pharmacol Exp Ther"},{"key":"r007","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1016\/S0022-3565(25)05200-0","volume":"107","author":"Axelrod","year":"1953","journal-title":"J Pharmacol Exp Ther"},{"key":"r008","doi-asserted-by":"publisher","DOI":"10.1007\/BF01308138"},{"key":"r009","first-page":"603","volume":"95","author":"Patwardhan","year":"1980","journal-title":"J Lab Clin Med"},{"key":"r010","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1111\/j.1365-2125.1981.tb01194.x","volume":"12","author":"Broughton","year":"1981","journal-title":"Br J Clin Pharmacol"},{"key":"r011","doi-asserted-by":"publisher","DOI":"10.1038\/clpt.1983.105"},{"key":"r012","first-page":"310","volume":"5","author":"Aldridge","year":"1981","journal-title":"Semin Perinatol"},{"key":"r013","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1002\/cpt197824140","volume":"24","author":"Parsons","year":"1978","journal-title":"Clin Pharmacol Ther"},{"key":"r014","doi-asserted-by":"crossref","first-page":"390","DOI":"10.1093\/ajcp\/73.3.390","volume":"73","author":"Statland","year":"1980","journal-title":"Am J Clin Pathol"},{"key":"r015","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1016\/S0022-3565(25)33447-6","volume":"224","author":"Tang-Liu","year":"1983","journal-title":"J Pharmacol Exp Ther"},{"key":"r016","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1016\/S0090-9556(25)07906-1","volume":"10","author":"Callahan","year":"1982","journal-title":"Drug Metab Dispos"},{"key":"r017","first-page":"185","volume":"13","author":"Sved","year":"1976","journal-title":"Res Commun Chem Pathol Pharmacol"},{"key":"r018","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(79)80247-4"},{"key":"r019","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1982.03330090067033"}],"container-title":["New England Journal of Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.nejm.org\/doi\/pdf\/10.1056\/NEJM198403223101202","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,2,23]],"date-time":"2025-02-23T14:36:21Z","timestamp":1740321381000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.nejm.org\/doi\/abs\/10.1056\/NEJM198403223101202"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1984,3,22]]},"references-count":19,"journal-issue":{"issue":"12","published-print":{"date-parts":[[1984,3,22]]}},"alternative-id":["10.1056\/NEJM198403223101202"],"URL":"https:\/\/doi.org\/10.1056\/nejm198403223101202","relation":{},"ISSN":["0028-4793","1533-4406"],"issn-type":[{"value":"0028-4793","type":"print"},{"value":"1533-4406","type":"electronic"}],"subject":[],"published":{"date-parts":[[1984,3,22]]}}}