{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,27]],"date-time":"2026-07-27T22:14:59Z","timestamp":1785190499135,"version":"3.55.0"},"reference-count":28,"publisher":"Massachusetts Medical Society","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["N Engl J Med"],"published-print":{"date-parts":[[1984,8,2]]},"DOI":"10.1056\/nejm198408023110504","type":"journal-article","created":{"date-parts":[[2010,7,28]],"date-time":"2010-07-28T21:29:33Z","timestamp":1280352573000},"page":"291-295","source":"Crossref","is-referenced-by-count":78,"title":["Effects of Oxygen Inhalation on Endogenous Erythropoietin Kinetics, Erythropoiesis, and Properties of Blood Cells in Sickle-Cell Anemia"],"prefix":"10.1056","volume":"311","author":[{"given":"Stephen H.","family":"Embury","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joseph F.","family":"Garcia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Narla","family":"Mohandas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rukmani","family":"Pennathur-Das","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Margaret R.","family":"Clark","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"150","reference":[{"key":"r001","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.133.4.698"},{"key":"r002","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.me.32.020181.001211"},{"key":"r003","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.133.4.577"},{"key":"r004","doi-asserted-by":"publisher","DOI":"10.1016\/0026-2862(75)90069-2"},{"key":"r005","unstructured":"Messer MJ, Hahn JA, Bradley TB. The kinetics of sickling and unsickling of red cells under physiologic conditions: rheologic and ultrastructural correlations. In: Hercules JI, ed. Proceedings of the Symposium on the Molecular and Cellular Aspects of Sickle Cell Disease. Bethesda, Md.: National Institutes of Health, 1976:225. (DHEW publication no. (NIH) 76\u20131007.)"},{"key":"r006","doi-asserted-by":"crossref","first-page":"653","DOI":"10.1182\/blood.V41.5.653.653","volume":"41","author":"Padilla","year":"1973","journal-title":"Blood"},{"key":"r007","doi-asserted-by":"crossref","first-page":"983","DOI":"10.1182\/blood.V51.5.983.983","volume":"51","author":"Glader","year":"1978","journal-title":"Blood"},{"key":"r008","first-page":"283","volume":"3","author":"Chien","year":"1977","journal-title":"Blood Cells"},{"key":"r009","doi-asserted-by":"publisher","DOI":"10.1172\/JCI109650"},{"key":"r010","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM197007232830402"},{"key":"r011","doi-asserted-by":"publisher","DOI":"10.1172\/JCI111055"},{"key":"r012","first-page":"400","volume":"96","author":"Bromberg","year":"1967","journal-title":"Am Rev Respir Dis"},{"key":"r013","doi-asserted-by":"publisher","DOI":"10.1172\/JCI101539"},{"key":"r014","doi-asserted-by":"publisher","DOI":"10.1172\/JCI102221"},{"key":"r015","doi-asserted-by":"crossref","first-page":"659","DOI":"10.1182\/blood.V60.3.659.659","volume":"60","author":"Clark","year":"1982","journal-title":"Blood"},{"key":"r016","first-page":"229","volume":"3","author":"Bessis","year":"1977","journal-title":"Blood Cells"},{"key":"r017","doi-asserted-by":"publisher","DOI":"10.1172\/JCI109888"},{"key":"r018","first-page":"405","volume":"5","author":"Garcia","year":"1979","journal-title":"Blood Cells"},{"key":"r019","unstructured":"Mayer SE, Melmon KL, Gilman AG. Introduction: the dynamics of drug absorption, distribution, and elimination. In: Gilman AG, Goodman LS, Gilman A, eds. Goodman and Gilman's the pharmacological basis of therapeutics. 6th ed. New York: Macmillan, 1980:1\u201327."},{"key":"r020","doi-asserted-by":"publisher","DOI":"10.1007\/BF01631465"},{"key":"r021","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.me.31.020180.001511"},{"key":"r022","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2141.1977.tb00559.x"},{"key":"r023","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2141.1981.tb07235.x"},{"key":"r024","doi-asserted-by":"publisher","DOI":"10.1172\/JCI105863"},{"key":"r025","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(78)90053-0"},{"key":"r026","doi-asserted-by":"crossref","first-page":"1169","DOI":"10.1182\/blood.V51.6.1169.1169","volume":"51","author":"Clark","year":"1978","journal-title":"Blood"},{"key":"r027","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2141.1978.tb05814.x"},{"key":"r028","first-page":"103","volume":"8","author":"Charache","year":"1982","journal-title":"Blood Cells"}],"container-title":["New England Journal of Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.nejm.org\/doi\/pdf\/10.1056\/NEJM198408023110504","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,6,9]],"date-time":"2020-06-09T17:40:43Z","timestamp":1591724443000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.nejm.org\/doi\/abs\/10.1056\/NEJM198408023110504"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1984,8,2]]},"references-count":28,"journal-issue":{"issue":"5","published-print":{"date-parts":[[1984,8,2]]}},"alternative-id":["10.1056\/NEJM198408023110504"],"URL":"https:\/\/doi.org\/10.1056\/nejm198408023110504","relation":{},"ISSN":["0028-4793","1533-4406"],"issn-type":[{"value":"0028-4793","type":"print"},{"value":"1533-4406","type":"electronic"}],"subject":[],"published":{"date-parts":[[1984,8,2]]}}}