{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,14]],"date-time":"2026-11-14T08:42:41Z","timestamp":1794645761811,"version":"4.9.1"},"reference-count":69,"publisher":"Massachusetts Medical Society","issue":"16","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["N Engl J Med"],"published-print":{"date-parts":[[1985,4,18]]},"DOI":"10.1056\/nejm198504183121606","type":"journal-article","created":{"date-parts":[[2010,7,28]],"date-time":"2010-07-28T21:30:55Z","timestamp":1280352655000},"page":"1035-1039","source":"Crossref","is-referenced-by-count":266,"title":["Wernicke's Encephalopathy"],"prefix":"10.1056","volume":"312","author":[{"given":"James B.","family":"Reuler","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Donald E.","family":"Girard","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas G.","family":"Cooney","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"150","reference":[{"key":"r001","doi-asserted-by":"publisher","DOI":"10.1172\/JCI102673"},{"key":"r002","unstructured":"Neal RA, Sauberlich HE. Thiamin. In: Goodhart RS, Shils ME, eds. Modern nutrition in health and disease. 6th ed. Philadelphia: Lea & Febiger, 1980:191\u20137."},{"key":"r003","doi-asserted-by":"crossref","first-page":"856","DOI":"10.1093\/ajcn\/34.5.856","volume":"34","author":"Shaw","year":"1981","journal-title":"Am J Clin Nutr"},{"key":"r004","doi-asserted-by":"crossref","first-page":"1341","DOI":"10.1093\/ajcn\/21.11.1341","volume":"21","author":"Tomasulo","year":"1968","journal-title":"Am J Clin Nutr"},{"key":"r005","doi-asserted-by":"crossref","first-page":"938","DOI":"10.1093\/ajcn\/31.6.938","volume":"31","author":"Hoyumpa","year":"1978","journal-title":"Am J Clin Nutr"},{"key":"r006","doi-asserted-by":"publisher","DOI":"10.3109\/00365528109181968"},{"key":"r007","doi-asserted-by":"publisher","DOI":"10.1172\/JCI105912"},{"key":"r008","unstructured":"Dreyfus PM. Thiamine-deficiency encephalopathy: thoughts on its pathogenesis. In: Gubler CJ, Fujiwara M, Dreyfus PM, eds. Thiamine. New York: John Wiley, 1974:229\u201339."},{"key":"r009","doi-asserted-by":"crossref","first-page":"2719","DOI":"10.1093\/ajcn\/33.12.2719","volume":"22","author":"Schenker","year":"1980","journal-title":"Am J Clin Nutr"},{"key":"r010","first-page":"77","volume":"86","author":"Henderson","year":"1975","journal-title":"J Lab Clin Med"},{"key":"r011","doi-asserted-by":"publisher","DOI":"10.1111\/j.1530-0277.1979.tb05286.x"},{"key":"r012","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM197712222972503"},{"key":"r013","unstructured":"Victor M, Adams RD, Collins GH. The Wernicke-Korsakoff syndrome. Philadelphia: FA Davis, 1971."},{"key":"r014","unstructured":"Adams RD, Victor M. Principles of neurology. 2nd ed. New York: McGraw-Hill, 1981:704\u201311."},{"key":"r015","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.2.6185.291"},{"key":"r016","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.42.3.226"},{"key":"r017","doi-asserted-by":"publisher","DOI":"10.1111\/j.1445-5994.1980.tb03720.x"},{"key":"r018","doi-asserted-by":"publisher","DOI":"10.1016\/0022-510X(82)90145-9"},{"key":"r019","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.1961.00450110040005"},{"key":"r020","first-page":"178","volume":"77","author":"Victor","year":"1952","journal-title":"Trans Am Neurol Assoc"},{"key":"r021","doi-asserted-by":"publisher","DOI":"10.1136\/pgmj.58.681.427"},{"key":"r022","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.1968.00470330038003"},{"key":"r023","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.32.2.134"},{"key":"r024","first-page":"777","volume":"52","author":"Tellez","year":"1968","journal-title":"Am J Pathol"},{"key":"r025","doi-asserted-by":"publisher","DOI":"10.1111\/j.1445-5994.1980.tb04098.x"},{"key":"r026","doi-asserted-by":"crossref","first-page":"504","DOI":"10.5694\/j.1326-5377.1980.tb100713.x","volume":"2","author":"Kearsley","year":"1980","journal-title":"Med J Aust"},{"key":"r027","first-page":"428","volume":"121","author":"Ackerman","year":"1974","journal-title":"West J Med"},{"key":"r028","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.1978.00500350054011"},{"key":"r029","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.1969.00480170065006"},{"key":"r030","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(73)93064-X"},{"key":"r031","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.15.6.836"},{"key":"r032","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(64)90167-6"},{"key":"r033","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(78)91867-6"},{"key":"r034","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.46.7.593"},{"key":"r035","first-page":"1122","volume":"1","year":"1979","journal-title":"Lancet"},{"key":"r036","doi-asserted-by":"publisher","DOI":"10.1159\/000114622"},{"key":"r037","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/102.4.749"},{"key":"r038","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.34.5.648"},{"key":"r039","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.1984.04050160119026"},{"key":"r040","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(82)90955-2"},{"key":"r041","unstructured":"Stockard JJ, Stockard JE, Sharbrough FW. brain-stem auditory evoked potentials in neurology: methodology, interpretation, clinical application. In: Aminoff MJ, ed. Electrodiagnosis in clinical neurology. New York: Churchill Livingstone, 1980:370\u2013413."},{"key":"r042","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM196209202671204"},{"key":"r043","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.nu.04.070184.002113"},{"key":"r044","doi-asserted-by":"publisher","DOI":"10.1111\/j.1445-5994.1977.tb03368.x"},{"key":"r045","doi-asserted-by":"publisher","DOI":"10.1192\/bjp.139.2.153"},{"key":"r046","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(78)92663-6"},{"key":"r047","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM196604282741705"},{"key":"r048","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(82)90039-3"},{"key":"r049","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1982.03320430070036"},{"key":"r050","doi-asserted-by":"publisher","DOI":"10.1136\/pgmj.58.683.558"},{"issue":"3","key":"r051","first-page":"13s","volume":"62","author":"Lavin","year":"1983","journal-title":"Obstet Gynecol"},{"key":"r052","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.1983.tb08974.x"},{"key":"r053","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM197601152940306"},{"key":"r054","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.22.12.1293"},{"key":"r055","first-page":"51","volume":"9","author":"Lasker","year":"1963","journal-title":"Trans Am Soc Artif Intern Organs"},{"key":"r056","doi-asserted-by":"crossref","first-page":"410","DOI":"10.1093\/ajcn\/39.3.410","volume":"39","author":"DeBari","year":"1984","journal-title":"Am J Clin Nutr"},{"key":"r057","doi-asserted-by":"publisher","DOI":"10.1007\/BF02938260"},{"key":"r058","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1976.03260480023023"},{"key":"r059","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.1980.00500530093030"},{"key":"r060","first-page":"48","volume":"43","author":"Baughman","year":"1976","journal-title":"Mt Sinai J Med"},{"key":"r061","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1977.03280210068028"},{"key":"r062","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1978.03280390029014"},{"key":"r063","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.1981.00510060052007"},{"key":"r064","first-page":"603","volume":"19","author":"Victor","year":"1978","journal-title":"Adv Neurol"},{"key":"r065","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1212\/WNL.31.4_Part_2.377","volume":"31","author":"Carlen","year":"1981","journal-title":"Neurology (NY)"},{"key":"r066","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1093\/ajcn\/22.1.44","volume":"22","author":"Cole","year":"1969","journal-title":"Am J Clin Nutr"},{"key":"r067","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM197808102990605"},{"key":"r068","doi-asserted-by":"crossref","first-page":"461","DOI":"10.5694\/j.1326-5377.1980.tb135039.x","volume":"1","author":"Wood","year":"1980","journal-title":"Med J Aust"},{"key":"r069","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM197808102990612"}],"container-title":["New England Journal of Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.nejm.org\/doi\/pdf\/10.1056\/NEJM198504183121606","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,6,9]],"date-time":"2020-06-09T17:42:15Z","timestamp":1591724535000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.nejm.org\/doi\/abs\/10.1056\/NEJM198504183121606"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1985,4,18]]},"references-count":69,"journal-issue":{"issue":"16","published-print":{"date-parts":[[1985,4,18]]}},"alternative-id":["10.1056\/NEJM198504183121606"],"URL":"https:\/\/doi.org\/10.1056\/nejm198504183121606","relation":{},"ISSN":["0028-4793","1533-4406"],"issn-type":[{"value":"0028-4793","type":"print"},{"value":"1533-4406","type":"electronic"}],"subject":[],"published":{"date-parts":[[1985,4,18]]}}}