{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T11:00:27Z","timestamp":1792839627208,"version":"4.5.0"},"reference-count":33,"publisher":"Massachusetts Medical Society","issue":"23","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["N Engl J Med"],"published-print":{"date-parts":[[1986,12,4]]},"DOI":"10.1056\/nejm198612043152304","type":"journal-article","created":{"date-parts":[[2010,7,28]],"date-time":"2010-07-28T21:38:47Z","timestamp":1280353127000},"page":"1448-1454","source":"Crossref","is-referenced-by-count":246,"title":["A Prospective Trial of Colchicine for Primary Biliary Cirrhosis"],"prefix":"10.1056","volume":"315","author":[{"given":"Marshall M.","family":"Kaplan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David W.","family":"Alling","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hyman J.","family":"Zimmerman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hubert J.","family":"Wolfe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert A.","family":"Sepersky","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gary S.","family":"Hirsch","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Grace H.","family":"Elta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kenneth A.","family":"Glick","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kathleen A.","family":"Eagen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"150","reference":[{"key":"r001","unstructured":"Sherlock S. Primary biliary cirrhosis. In: Wright R, Alberti KGMM, Karran S. Millward-Sadler GH. eds. Liver and biliary disease: pathophysiology, diagnosis, management. Philadelphia: WB Saunders, 1979:715\u201334."},{"key":"r002","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1016\/S0016-5085(55)80027-3","volume":"28","author":"Carman","year":"1955","journal-title":"Gastroenterology"},{"key":"r003","first-page":"227","volume":"16","author":"Howat","year":"1966","journal-title":"Rev Int Hepatol"},{"key":"r004","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/S0016-5085(82)80291-6","volume":"83","author":"Matloff","year":"1982","journal-title":"Gastroenterology"},{"key":"r005","doi-asserted-by":"crossref","first-page":"656","DOI":"10.1016\/S0016-5085(76)80250-8","volume":"70","author":"Heathcote","year":"1976","journal-title":"Gastroenterology"},{"key":"r006","doi-asserted-by":"crossref","first-page":"1005","DOI":"10.1016\/0016-5085(80)90784-2","volume":"78","author":"Crowe","year":"1980","journal-title":"Gastroenterology"},{"key":"r007","doi-asserted-by":"crossref","first-page":"1084","DOI":"10.1016\/0016-5085(85)90213-6","volume":"89","author":"Christensen","year":"1985","journal-title":"Gastroenterology"},{"key":"r008","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198202113060602"},{"key":"r009","first-page":"A909","volume":"23","author":"Bassendine","year":"1982","journal-title":"Gut"},{"key":"r010","doi-asserted-by":"publisher","DOI":"10.1136\/gut.26.2.114"},{"key":"r011","first-page":"A919","volume":"21","author":"Triger","year":"1980","journal-title":"Gut"},{"key":"r012","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1111\/j.1600-0676.1983.tb00887.x","volume":"3","author":"Taal","year":"1983","journal-title":"Liver"},{"key":"r013","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198504183121602"},{"key":"r014","first-page":"1032","volume":"4","author":"Epstein","year":"1984","journal-title":"Hepatology"},{"key":"r015","doi-asserted-by":"crossref","first-page":"532","DOI":"10.1016\/0016-5085(79)90018-0","volume":"77","author":"Kirshenobich","year":"1979","journal-title":"Gastroenterology"},{"key":"r016","first-page":"1309","volume":"78","author":"Koldinger","year":"1980","journal-title":"Gastroenterology"},{"key":"r017","doi-asserted-by":"publisher","DOI":"10.1136\/gut.26.2.109"},{"key":"r018","unstructured":"Scheuer PM. Liver biopsy interpretation. 2nd ed. Baltimore: Williams & Wilkins, 1973:33\u20138."},{"key":"r019","doi-asserted-by":"publisher","DOI":"10.2307\/2529595"},{"key":"r020","doi-asserted-by":"publisher","DOI":"10.1016\/0021-9681(58)90126-7"},{"key":"r021","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM197410312911804"},{"key":"r022","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(73)91248-8"},{"key":"r023","doi-asserted-by":"publisher","DOI":"10.1055\/s-2008-1040738"},{"key":"r024","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198301063080101"},{"key":"r025","first-page":"1022","volume":"4","author":"Warnes","year":"1984","journal-title":"Hepatology"},{"key":"r026","doi-asserted-by":"publisher","DOI":"10.1002\/hep.1840050613"},{"key":"r027","doi-asserted-by":"crossref","first-page":"820","DOI":"10.1016\/S0016-5085(19)33223-8","volume":"63","author":"Soloway","year":"1972","journal-title":"Gastroenterology"},{"key":"r028","unstructured":"Salaspuro MP, Lieber CS. Alcoholic liver disease. In: Wright R, Alberti KGMM, Karran S, Millward-Sadler GH, eds. Liver and biliary disease: pathophysiology, diagnosis, management. London: WB Saunders, 1979: 735\u201373."},{"key":"r029","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.bi.42.070173.002451"},{"key":"r030","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.69.4.892"},{"key":"r031","doi-asserted-by":"publisher","DOI":"10.1002\/art.1780140602"},{"key":"r032","doi-asserted-by":"publisher","DOI":"10.1016\/0005-2787(75)90186-0"},{"key":"r033","doi-asserted-by":"publisher","DOI":"10.1002\/art.1780190315"}],"container-title":["New England Journal of Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.nejm.org\/doi\/pdf\/10.1056\/NEJM198612043152304","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,6,9]],"date-time":"2020-06-09T17:48:57Z","timestamp":1591724937000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.nejm.org\/doi\/abs\/10.1056\/NEJM198612043152304"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1986,12,4]]},"references-count":33,"journal-issue":{"issue":"23","published-print":{"date-parts":[[1986,12,4]]}},"alternative-id":["10.1056\/NEJM198612043152304"],"URL":"https:\/\/doi.org\/10.1056\/nejm198612043152304","relation":{},"ISSN":["0028-4793","1533-4406"],"issn-type":[{"value":"0028-4793","type":"print"},{"value":"1533-4406","type":"electronic"}],"subject":[],"published":{"date-parts":[[1986,12,4]]}}}