{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,15]],"date-time":"2026-11-15T01:11:33Z","timestamp":1794705093287,"version":"4.9.1"},"reference-count":26,"publisher":"Massachusetts Medical Society","issue":"15","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["N Engl J Med"],"published-print":{"date-parts":[[1991,10,10]]},"DOI":"10.1056\/nejm199110103251504","type":"journal-article","created":{"date-parts":[[2010,7,28]],"date-time":"2010-07-28T21:59:06Z","timestamp":1280354346000},"page":"1067-1071","source":"Crossref","is-referenced-by-count":591,"title":["Relation between Airway Responsiveness and Serum IgE in Children with Asthma and in Apparently Normal Children"],"prefix":"10.1056","volume":"325","author":[{"given":"M.R.","family":"Sears","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B.","family":"Burrows","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.M.","family":"Flannery","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G.P.","family":"Herbison","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.J.","family":"Hewitt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.D.","family":"Holdaway","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"150","reference":[{"key":"r001","doi-asserted-by":"publisher","DOI":"10.1016\/0091-6749(88)90221-7"},{"key":"r002","doi-asserted-by":"publisher","DOI":"10.1136\/thx.31.4.419"},{"key":"r003","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198902023200502"},{"key":"r004","doi-asserted-by":"publisher","DOI":"10.1136\/thx.37.6.423"},{"key":"r005","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.286.6373.1256"},{"key":"r006","doi-asserted-by":"publisher","DOI":"10.1136\/thx.41.4.283"},{"key":"r007","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2222.1987.tb02015.x"},{"key":"r008","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-3016.1990.tb00621.x"},{"key":"r009","doi-asserted-by":"publisher","DOI":"10.1016\/0007-0971(87)90181-1"},{"key":"r010","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2222.1976.tb01417.x"},{"key":"r011","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2222.1977.tb01448.x"},{"key":"r012","doi-asserted-by":"publisher","DOI":"10.1016\/S0091-6749(74)80006-0"},{"key":"r013","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2222.1976.tb01919.x"},{"key":"r014","doi-asserted-by":"publisher","DOI":"10.1016\/0091-6749(83)90520-1"},{"key":"r015","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2222.1978.tb00460.x"},{"key":"r016","doi-asserted-by":"crossref","first-page":"1520","DOI":"10.1164\/ajrccm\/140.6.1520","volume":"140","author":"O'Connor","year":"1989","journal-title":"Am Rev Respir Dis"},{"key":"r017","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2222.1990.tb02665.x"},{"key":"r018","first-page":"26","volume":"53","author":"Cockcroft","year":"1984","journal-title":"Ann Allergy"},{"key":"r019","doi-asserted-by":"publisher","DOI":"10.1136\/thx.44.5.425"},{"key":"r020","doi-asserted-by":"publisher","DOI":"10.1378\/chest.84.6.657"},{"key":"r021","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1164\/arrd.1983.128.1.8","volume":"128","author":"Malo","year":"1983","journal-title":"Am Rev Respir Dis"},{"key":"r022","doi-asserted-by":"crossref","first-page":"826","DOI":"10.1164\/ajrccm\/137.4.826","volume":"137","author":"Rijcken","year":"1988","journal-title":"Am Rev Respir Dis"},{"key":"r023","doi-asserted-by":"publisher","DOI":"10.1016\/0091-6749(75)90061-5"},{"key":"r024","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2222.1977.tb01481.x"},{"key":"r025","doi-asserted-by":"publisher","DOI":"10.1016\/0091-6749(83)90069-6"},{"key":"r026","doi-asserted-by":"publisher","DOI":"10.1016\/0091-6749(89)90441-7"}],"container-title":["New England Journal of Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.nejm.org\/doi\/pdf\/10.1056\/NEJM199110103251504","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,31]],"date-time":"2019-05-31T23:15:37Z","timestamp":1559344537000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.nejm.org\/doi\/abs\/10.1056\/NEJM199110103251504"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1991,10,10]]},"references-count":26,"journal-issue":{"issue":"15","published-print":{"date-parts":[[1991,10,10]]}},"alternative-id":["10.1056\/NEJM199110103251504"],"URL":"https:\/\/doi.org\/10.1056\/nejm199110103251504","relation":{},"ISSN":["0028-4793","1533-4406"],"issn-type":[{"value":"0028-4793","type":"print"},{"value":"1533-4406","type":"electronic"}],"subject":[],"published":{"date-parts":[[1991,10,10]]}}}