{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T03:05:24Z","timestamp":1790737524769,"version":"4.1.0"},"reference-count":39,"publisher":"Massachusetts Medical Society","issue":"26","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["N Engl J Med"],"published-print":{"date-parts":[[1992,12,24]]},"DOI":"10.1056\/nejm199212243272603","type":"journal-article","created":{"date-parts":[[2010,7,28]],"date-time":"2010-07-28T18:02:28Z","timestamp":1280340148000},"page":"1836-1841","source":"Crossref","is-referenced-by-count":218,"title":["A Controlled Trial of Aerosolized Pentamidine or Trimethoprim\u2013Sulfamethoxazole as Primary Prophylaxis against\n                    <i>Pneumocystis carinii<\/i>\n                    Pneumonia in Patients with Human Immunodeficiency Virus Infection"],"prefix":"10.1056","volume":"327","author":[{"given":"Margriet M.E.","family":"Schneider","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andy I.M.","family":"Hoepelman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jan Karel M. Eeftinck","family":"Schattenkerk","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thyge L.","family":"Nielsen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yolanda","family":"van der Graaf","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos P.H.J.","family":"Frissen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ineke M.E.","family":"van der Ende","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ad F.P.","family":"Kolsters","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jan C.C.","family":"Borleffs","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"150","reference":[{"key":"r001","doi-asserted-by":"publisher","DOI":"10.1001\/jama.262.3.335"},{"key":"r002","doi-asserted-by":"crossref","first-page":"663","DOI":"10.7326\/0003-4819-100-5-663","volume":"100","author":"Kovacs","year":"1984","journal-title":"Ann Intern Med"},{"key":"r003","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/160.5.882"},{"key":"r004","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198406213102529"},{"key":"r005","first-page":"17","volume":"35","year":"1986","journal-title":"MMWR Morb Mortal Wkly Rep"},{"key":"r006","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198806023182206"},{"key":"r007","doi-asserted-by":"crossref","first-page":"223","DOI":"10.7326\/0003-4819-111-3-223","volume":"111","author":"Masur","year":"1989","journal-title":"Ann Intern Med"},{"key":"r008","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199001183220304"},{"key":"r009","first-page":"770","volume":"4","author":"Crowe","year":"1991","journal-title":"J Acquir Immune Defic Syndr"},{"key":"r010","doi-asserted-by":"publisher","DOI":"10.1016\/0140-6736(91)90414-K"},{"key":"r011","first-page":"1","volume":"38","year":"1989","journal-title":"MMWR Morb Mortal Wkly Rep"},{"key":"r012","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199009203231201"},{"key":"r013","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199104183241602"},{"key":"r014","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(89)92153-3"},{"key":"r015","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(89)92802-X"},{"key":"r016","doi-asserted-by":"crossref","first-page":"948","DOI":"10.7326\/0003-4819-114-11-948","volume":"114","author":"Montaner","year":"1991","journal-title":"Ann Intern Med"},{"key":"r017","doi-asserted-by":"publisher","DOI":"10.1097\/00002030-199202000-00004"},{"key":"r018","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/27.2.153"},{"key":"r019","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(89)92060-6"},{"key":"r020","first-page":"1092","volume":"316","author":"Macher","year":"1987","journal-title":"N Engl J Med"},{"key":"r021","doi-asserted-by":"publisher","DOI":"10.1093\/clinids\/12.3.380"},{"key":"r022","doi-asserted-by":"publisher","DOI":"10.1001\/jama.259.8.1185"},{"key":"r023","doi-asserted-by":"publisher","DOI":"10.1016\/0140-6736(91)93402-U"},{"key":"r024","first-page":"1155","volume":"317","author":"Flanigan","year":"1987","journal-title":"N Engl J Med"},{"key":"r025","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198707233170402"},{"key":"r026","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198706253162604"},{"key":"r027","doi-asserted-by":"crossref","first-page":"1705","DOI":"10.1128\/AAC.35.9.1705","volume":"35","author":"Stein","year":"1991","journal-title":"Antimicrob Agents Chemother"},{"key":"r028","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.151.4.688"},{"key":"r029","doi-asserted-by":"publisher","DOI":"10.2307\/2281868"},{"key":"r030","unstructured":"EGRET statistical package. Seattle: Statistics and Epidemiology Research, 1990."},{"key":"r031","unstructured":"SAS\/STAT guide for personal computers, version 6 ed. Cary, N.C.: SAS Institute, 1985."},{"key":"r032","first-page":"1S","volume":"36","year":"1987","journal-title":"MMWR Morb Mortal Wkly Rep"},{"key":"r033","doi-asserted-by":"publisher","DOI":"10.1136\/thx.44.7.591"},{"key":"r034","doi-asserted-by":"publisher","DOI":"10.1378\/chest.94.2.329"},{"key":"r035","doi-asserted-by":"publisher","DOI":"10.1016\/0140-6736(91)92910-T"},{"key":"r036","doi-asserted-by":"publisher","DOI":"10.1016\/0140-6736(91)91046-W"},{"key":"r037","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(89)91909-0"},{"key":"r038","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199109053251013"},{"key":"r039","doi-asserted-by":"publisher","DOI":"10.1001\/jama.266.6.820"}],"container-title":["New England Journal of Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.nejm.org\/doi\/pdf\/10.1056\/NEJM199212243272603","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,31]],"date-time":"2019-05-31T19:21:06Z","timestamp":1559330466000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.nejm.org\/doi\/abs\/10.1056\/NEJM199212243272603"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1992,12,24]]},"references-count":39,"journal-issue":{"issue":"26","published-print":{"date-parts":[[1992,12,24]]}},"alternative-id":["10.1056\/NEJM199212243272603"],"URL":"https:\/\/doi.org\/10.1056\/nejm199212243272603","relation":{},"ISSN":["0028-4793","1533-4406"],"issn-type":[{"value":"0028-4793","type":"print"},{"value":"1533-4406","type":"electronic"}],"subject":[],"published":{"date-parts":[[1992,12,24]]}}}