{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,13]],"date-time":"2026-11-13T09:23:19Z","timestamp":1794561799125,"version":"4.9.1"},"reference-count":83,"publisher":"Massachusetts Medical Society","issue":"7","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["N Engl J Med"],"published-print":{"date-parts":[[1996,2,15]]},"DOI":"10.1056\/nejm199602153340707","type":"journal-article","created":{"date-parts":[[2002,7,27]],"date-time":"2002-07-27T12:51:35Z","timestamp":1027774295000},"page":"445-451","source":"Crossref","is-referenced-by-count":401,"title":["The Management of Gout"],"prefix":"10.1056","volume":"334","author":[{"given":"Bryan T.","family":"Emmerson","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"150","reference":[{"key":"r001","doi-asserted-by":"publisher","DOI":"10.1002\/art.1780200320"},{"key":"r002","doi-asserted-by":"publisher","DOI":"10.1002\/art.1780220521"},{"key":"r003","doi-asserted-by":"publisher","DOI":"10.1002\/art.1780291209"},{"key":"r004","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.152.4.873"},{"key":"r005","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/24.2.155"},{"key":"r006","doi-asserted-by":"publisher","DOI":"10.1016\/0021-9681(76)90003-5"},{"key":"r007","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(87)90441-4"},{"key":"r008","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(79)90076-7"},{"key":"r009","doi-asserted-by":"publisher","DOI":"10.1111\/j.1445-5994.1987.tb01232.x"},{"key":"r010","doi-asserted-by":"publisher","DOI":"10.1016\/0049-0172(81)90001-9"},{"key":"r011","doi-asserted-by":"publisher","DOI":"10.1002\/art.1780310618"},{"key":"r012","first-page":"111","volume":"20","author":"Alloway JA","year":"1993","journal-title":"J Rheumatol"},{"key":"r013","doi-asserted-by":"publisher","DOI":"10.1016\/0049-0172(90)90070-V"},{"key":"r014","doi-asserted-by":"publisher","DOI":"10.1172\/JCI109523"},{"key":"r015","doi-asserted-by":"publisher","DOI":"10.1172\/JCI116759"},{"key":"r016","first-page":"494","volume":"19","author":"Caraco Y","year":"1992","journal-title":"J Rheumatol"},{"key":"r017","doi-asserted-by":"crossref","first-page":"257","DOI":"10.7326\/0003-4819-114-4-257","volume":"114","author":"Griffin MR","year":"1991","journal-title":"Ann Intern Med"},{"key":"r018","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.300.6720.278"},{"key":"r019","first-page":"912","volume":"15","author":"Roth SH","year":"1988","journal-title":"J Rheumatol"},{"key":"r020","doi-asserted-by":"publisher","DOI":"10.1001\/jama.244.10.1127"},{"key":"r021","doi-asserted-by":"publisher","DOI":"10.1136\/ard.46.3.233"},{"key":"r022","doi-asserted-by":"crossref","first-page":"179","DOI":"10.7326\/0003-4819-55-2-179","volume":"55","author":"Yu TF","year":"1961","journal-title":"Ann Intern Med"},{"key":"r023","doi-asserted-by":"publisher","DOI":"10.1016\/0049-0172(82)90065-8"},{"key":"r024","first-page":"600","volume":"19","author":"Pascual E","year":"1992","journal-title":"J Rheumatol"},{"key":"r025","doi-asserted-by":"crossref","first-page":"182","DOI":"10.5694\/j.1326-5377.1993.tb137784.x","volume":"159","author":"Kot TV","year":"1993","journal-title":"Med J Aust"},{"key":"r026","doi-asserted-by":"publisher","DOI":"10.1172\/JCI102505"},{"key":"r027","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.1971.tb46916.x"},{"key":"r028","doi-asserted-by":"publisher","DOI":"10.1007\/BF00614010"},{"key":"r029","doi-asserted-by":"publisher","DOI":"10.1002\/cpt1979265611"},{"key":"r030","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.281.6239.531"},{"key":"r031","first-page":"423","volume":"45","author":"Kovalchik MT","year":"1981","journal-title":"Conn Med"},{"key":"r032","doi-asserted-by":"crossref","first-page":"542","DOI":"10.3181\/00379727-90-22094","volume":"90","author":"Yu TF","year":"1955","journal-title":"Proc Soc Exp Biol Med"},{"key":"r033","first-page":"335","volume":"14","author":"Emmerson BT","year":"1987","journal-title":"J Rheumatol"},{"key":"r034","doi-asserted-by":"publisher","DOI":"10.1002\/art.1780190209"},{"key":"r035","first-page":"126","volume":"76","author":"Rundles RW","year":"1963","journal-title":"Trans Assoc Am Physicians"},{"key":"r036","doi-asserted-by":"publisher","DOI":"10.1016\/0006-2952(77)90191-5"},{"key":"r037","doi-asserted-by":"publisher","DOI":"10.1002\/cpt1978235598"},{"key":"r038","doi-asserted-by":"publisher","DOI":"10.1001\/jama.257.14.1920"},{"key":"r039","first-page":"495","volume":"15","author":"Wallace SL","year":"1988","journal-title":"J Rheumatol"},{"key":"r040","doi-asserted-by":"crossref","first-page":"4889","DOI":"10.1111\/j.1365-2125.1988.tb03412.x","volume":"26","author":"Arnold MH","year":"1988","journal-title":"Br J Clin Pharmacol"},{"key":"r041","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.2.5547.272"},{"key":"r042","first-page":"163","volume":"2","author":"Calabro JJ","year":"1974","journal-title":"Acta Reuma Port"},{"key":"r043","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(82)90579-4"},{"key":"r044","first-page":"66","volume":"72","author":"Bluestone RH","year":"1982","journal-title":"Am J Med"},{"key":"r045","doi-asserted-by":"publisher","DOI":"10.1001\/jama.239.1.34"},{"key":"r046","first-page":"1422","volume":"15","author":"Altman RD","year":"1988","journal-title":"J Rheumatol"},{"key":"r047","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198706183162502"},{"key":"r048","first-page":"264","volume":"18","author":"Wallace SL","year":"1991","journal-title":"J Rheumatol"},{"key":"r049","doi-asserted-by":"publisher","DOI":"10.1002\/art.1780351218"},{"key":"r050","doi-asserted-by":"publisher","DOI":"10.1177\/096032719201100612"},{"key":"r051","doi-asserted-by":"publisher","DOI":"10.1016\/0026-0495(81)90142-6"},{"key":"r052","doi-asserted-by":"publisher","DOI":"10.1001\/jama.266.21.3004"},{"key":"r053","doi-asserted-by":"publisher","DOI":"10.1111\/j.1445-5994.1973.tb03115.x"},{"key":"r054","first-page":"375","volume":"13","author":"Modan M","year":"1987","journal-title":"Diabetes Metab"},{"key":"r055","doi-asserted-by":"publisher","DOI":"10.1001\/jama.266.21.3008"},{"key":"r056","first-page":"255","volume":"10","author":"Yamashita S","year":"1986","journal-title":"Int J Obes"},{"key":"r057","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/23.3.203"},{"key":"r058","doi-asserted-by":"crossref","unstructured":"Emmerson BT. Abnormal urate excretion associated with renal and systemic disorders, drugs, and toxins. In: Kelley WN, Weiner IM, eds. Uric acid. Vol. 51 of Handbook of experimental pharmacology. Berlin, Germany: Springer-Verlag, 1978:287-324.","DOI":"10.1007\/978-3-642-66867-8_11"},{"key":"r059","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(57)90231-0"},{"key":"r060","doi-asserted-by":"publisher","DOI":"10.1136\/ard.51.3.375"},{"key":"r061","doi-asserted-by":"publisher","DOI":"10.1016\/0026-0495(68)90065-6"},{"key":"r062","doi-asserted-by":"publisher","DOI":"10.1136\/ard.51.2.259"},{"key":"r063","doi-asserted-by":"publisher","DOI":"10.1016\/0140-6736(91)93141-U"},{"key":"r065","first-page":"423","volume":"42","author":"Emmerson BT","year":"1973","journal-title":"Q J Med"},{"key":"r066","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1111\/j.1365-2125.1988.tb03401.x","volume":"26","author":"Day RO","year":"1988","journal-title":"Br J Clin Pharmacol"},{"key":"r067","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/26.6.445"},{"key":"r068","doi-asserted-by":"publisher","DOI":"10.1136\/ard.25.Suppl_6.655"},{"key":"r069","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2796.1990.tb00195.x"},{"key":"r070","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM197203092861002"},{"key":"r071","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(84)90743-5"},{"key":"r072","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.134.3.553"},{"key":"r073","first-page":"194","volume":"52","author":"Pusey CD","year":"1983","journal-title":"Q J Med"},{"key":"r074","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.2.6033.458"},{"key":"r075","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(92)90236-5"},{"key":"r076","doi-asserted-by":"publisher","DOI":"10.1002\/art.1780310318"},{"key":"r078","doi-asserted-by":"crossref","first-page":"750","DOI":"10.1016\/S0022-5347(17)62244-4","volume":"102","author":"Smith MJV","year":"1969","journal-title":"J Urol"},{"key":"r079","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198611273152204"},{"key":"r080","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1016\/S0022-3476(86)80387-0","volume":"190","author":"Andreoli SP","year":"1986","journal-title":"J Pediatr"},{"key":"r081","doi-asserted-by":"publisher","DOI":"10.1016\/0009-8981(86)90141-5"},{"key":"r082","doi-asserted-by":"publisher","DOI":"10.1002\/art.1780340812"},{"key":"r083","first-page":"1246","volume":"16","author":"Bull PW","year":"1989","journal-title":"J Rheumatol"},{"key":"r084","first-page":"1383","volume":"20","author":"van Lieshout-Zuidema MF","year":"1993","journal-title":"J Rheumatol"},{"key":"r085","doi-asserted-by":"publisher","DOI":"10.1007\/BF02125830"}],"container-title":["New England Journal of Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.nejm.org\/doi\/pdf\/10.1056\/NEJM199602153340707","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,3,5]],"date-time":"2020-03-05T12:12:03Z","timestamp":1583410323000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.nejm.org\/doi\/10.1056\/NEJM199602153340707"}},"subtitle":[],"editor":[{"given":"Alastair J.J.","family":"Wood","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[1996,2,15]]},"references-count":83,"journal-issue":{"issue":"7","published-print":{"date-parts":[[1996,2,15]]}},"alternative-id":["10.1056\/NEJM199602153340707"],"URL":"https:\/\/doi.org\/10.1056\/nejm199602153340707","relation":{},"ISSN":["0028-4793","1533-4406"],"issn-type":[{"value":"0028-4793","type":"print"},{"value":"1533-4406","type":"electronic"}],"subject":[],"published":{"date-parts":[[1996,2,15]]}}}