{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T22:33:38Z","timestamp":1792794818811,"version":"4.5.0"},"reference-count":117,"publisher":"Massachusetts Medical Society","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["N Engl J Med"],"published-print":{"date-parts":[[1996,7,11]]},"DOI":"10.1056\/nejm199607113350206","type":"journal-article","created":{"date-parts":[[2002,7,27]],"date-time":"2002-07-27T12:52:53Z","timestamp":1027774373000},"page":"99-107","source":"Crossref","is-referenced-by-count":593,"title":["Chronic Autoimmune Thyroiditis"],"prefix":"10.1056","volume":"335","author":[{"given":"Colin M.","family":"Dayan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gilbert H.","family":"Daniels","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"150","reference":[{"key":"r001","first-page":"219","volume":"97","author":"Hashimoto H","year":"1912","journal-title":"Arch Klin Chir"},{"key":"r002","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(56)92249-8"},{"key":"r003","unstructured":"Nagataki S. The concept of Hashimoto disease. In: Nagataki S, Mori T, Torizuka K, eds. 80 Years of Hashimoto disease. Amsterdam: Elsevier Science, 1993:539-45."},{"key":"r004","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1007\/BF03350006","volume":"12","author":"Costa A","year":"1989","journal-title":"J Endocrinol Invest"},{"key":"r005","unstructured":"Volp\u00e9 R. Autoimmune thyroiditis. In: Braverman LE, Utiger RD, eds. Werner and Ingbar's the thyroid: a fundamental and clinical text. 6th ed. Philadelphia: J.B. Lippincott, 1991:921-33."},{"key":"r006","doi-asserted-by":"crossref","first-page":"836","DOI":"10.1016\/S0025-6196(12)64789-2","volume":"60","author":"Hay ID","year":"1985","journal-title":"Mayo Clin Proc"},{"key":"r007","doi-asserted-by":"publisher","DOI":"10.1089\/thy.1994.4.333"},{"key":"r008","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM196102022640505"},{"key":"r009","doi-asserted-by":"publisher","DOI":"10.1210\/jcem-61-6-1172"},{"key":"r010","first-page":"788","volume":"15","author":"Weetman AP","year":"1994","journal-title":"Endocr Rev"},{"key":"r011","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.88.16.7415"},{"key":"r012","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199107253250404"},{"key":"r013","doi-asserted-by":"crossref","first-page":"3884","DOI":"10.4049\/jimmunol.151.7.3884","volume":"151","author":"McIntosh RS","year":"1993","journal-title":"J Immunol"},{"key":"r014","doi-asserted-by":"publisher","DOI":"10.1111\/j.0954-6820.1986.tb03283.x"},{"key":"r015","first-page":"107","volume":"14","author":"Tomer Y","year":"1993","journal-title":"Endocr Rev"},{"key":"r016","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1093\/milmed\/156.2.93","volume":"156","author":"Drabick JJ","year":"1991","journal-title":"Mil Med"},{"key":"r017","doi-asserted-by":"publisher","DOI":"10.3109\/08916939209014629"},{"key":"r018","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(83)90628-1"},{"key":"r019","first-page":"265","volume":"61","author":"Todd I","year":"1985","journal-title":"Clin Exp Immunol"},{"key":"r020","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(83)90629-3"},{"key":"r021","doi-asserted-by":"publisher","DOI":"10.1126\/science.3871967"},{"key":"r022","first-page":"231","volume":"87","author":"Tandon N","year":"1994","journal-title":"Q J Med"},{"key":"r023","doi-asserted-by":"publisher","DOI":"10.1016\/0014-5793(85)80446-4"},{"key":"r024","doi-asserted-by":"publisher","DOI":"10.1210\/edrv-8-4-448"},{"key":"r025","first-page":"140","volume":"65","author":"Del Prete GF","year":"1986","journal-title":"Clin Exp Immunol"},{"key":"r026","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2249.1991.tb05749.x"},{"key":"r027","first-page":"316","volume":"45","author":"Khoury EL","year":"1981","journal-title":"Clin Exp Immunol"},{"key":"r028","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1530\/acta.0.1230431","volume":"123","author":"Bogner U","year":"1990","journal-title":"Acta Endocrinol Suppl (Copenh)"},{"key":"r029","doi-asserted-by":"publisher","DOI":"10.1210\/jc.77.6.1700"},{"key":"r030","first-page":"25","volume":"77","author":"Weetman AP","year":"1989","journal-title":"Clin Exp Immunol"},{"key":"r031","unstructured":"Konishi J, Kasagi K, Iida Y. Thyroid stimulation blocking antibodies \u2014 an overview. In: Nagataki S, Mori T, Torizuka K, eds. 80 Years of Hashimoto disease. Amsterdam: Elsevier Science, 1993:573-7."},{"key":"r032","doi-asserted-by":"publisher","DOI":"10.1210\/jcem-71-5-1382"},{"key":"r033","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199202203260803"},{"key":"r034","doi-asserted-by":"publisher","DOI":"10.1210\/jcem-70-3-742"},{"key":"r035","doi-asserted-by":"publisher","DOI":"10.1210\/jcem-72-5-973"},{"key":"r036","first-page":"727","volume":"2","author":"Roitt IM","year":"1967","journal-title":"Clin Exp Immunol"},{"key":"r037","doi-asserted-by":"publisher","DOI":"10.1210\/jcem-45-1-45"},{"key":"r038","doi-asserted-by":"publisher","DOI":"10.1210\/jcem-69-6-1268"},{"key":"r039","doi-asserted-by":"publisher","DOI":"10.1210\/jc.78.1.94"},{"key":"r040","doi-asserted-by":"publisher","DOI":"10.1210\/jc.74.3.496"},{"key":"r041","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2265.1992.tb01475.x"},{"key":"r042","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2265.1991.tb03502.x"},{"key":"r043","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2265.1994.tb01835.x"},{"key":"r044","doi-asserted-by":"publisher","DOI":"10.1210\/jc.79.1.17"},{"key":"r045","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1530\/acta.0.1080055","volume":"108","author":"Harach HR","year":"1985","journal-title":"Acta Endocrinol (Copenh)"},{"key":"r046","doi-asserted-by":"publisher","DOI":"10.1210\/jcem-57-4-859"},{"key":"r047","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2265.1991.tb00314.x"},{"key":"r048","doi-asserted-by":"publisher","DOI":"10.1210\/jc.78.2.393"},{"key":"r049","doi-asserted-by":"publisher","DOI":"10.1210\/jcem-32-4-515"},{"key":"r050","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(91)90187-3"},{"key":"r051","doi-asserted-by":"publisher","DOI":"10.1210\/jcem-36-2-338"},{"key":"r052","doi-asserted-by":"publisher","DOI":"10.1017\/S0033291700053307"},{"key":"r053","doi-asserted-by":"publisher","DOI":"10.1210\/jcem-63-5-1086"},{"key":"r054","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(92)90278-J"},{"key":"r055","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2249.1992.tb05852.x"},{"key":"r056","doi-asserted-by":"publisher","DOI":"10.1210\/jc.80.3.922"},{"key":"r057","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198806163182401"},{"key":"r058","doi-asserted-by":"publisher","DOI":"10.1016\/0140-6736(91)91103-2"},{"key":"r059","first-page":"399","volume":"89","author":"Watanabe U","year":"1994","journal-title":"Am J Gastroenterol"},{"key":"r060","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(85)92785-0"},{"key":"r061","doi-asserted-by":"publisher","DOI":"10.1002\/path.1700830127"},{"key":"r062","doi-asserted-by":"crossref","first-page":"698","DOI":"10.1093\/ajcp\/101.6.698","volume":"101","author":"Okayasu I","year":"1994","journal-title":"Am J Clin Pathol"},{"key":"r063","doi-asserted-by":"publisher","DOI":"10.1210\/jcem-71-3-661"},{"key":"r064","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2265.1976.tb02822.x"},{"key":"r065","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2265.1977.tb01340.x"},{"key":"r066","doi-asserted-by":"crossref","first-page":"511","DOI":"10.5694\/j.1326-5377.1978.tb131681.x","volume":"2","author":"Barbato MP","year":"1978","journal-title":"Med J Aust"},{"key":"r067","doi-asserted-by":"publisher","DOI":"10.1016\/0140-6736(92)91265-A"},{"key":"r068","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2265.1991.tb01739.x"},{"key":"r069","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.150.4.785"},{"key":"r070","first-page":"S","volume":"4","author":"Ladenson PW","year":"1994","journal-title":"Thyroid"},{"key":"r071","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.145.8.1386"},{"key":"r072","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2265.1995.tb01894.x"},{"key":"r073","doi-asserted-by":"publisher","DOI":"10.1016\/S0300-595X(79)80010-9"},{"key":"r074","unstructured":"Tsuboi K, Yuasa R, Tanaka Y, Ueshiba H, Takeda S, Ito K. Incidence of thyroid atrophy in patients with Hashimoto thyroiditis. In: Nagataki S, Mori T, Torizuka K, eds. 80 Years of Hashimoto disease. Amsterdam: Elsevier Science, 1993:69-72."},{"key":"r075","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(91)90153-O"},{"key":"r076","doi-asserted-by":"publisher","DOI":"10.1016\/S0046-8177(74)80063-8"},{"key":"r077","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1007\/BF03350281","volume":"14","author":"Sostre S","year":"1991","journal-title":"J Endocrinol Invest"},{"key":"r078","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1530\/acta.0.1220391","volume":"122","author":"Nordmeyer JP","year":"1990","journal-title":"Acta Endocrinol (Copenh)"},{"key":"r079","doi-asserted-by":"crossref","first-page":"355","DOI":"10.7326\/0003-4819-104-3-355","volume":"104","author":"Zimmerman RS","year":"1986","journal-title":"Ann Intern Med"},{"key":"r080","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.153.7.862"},{"key":"r081","doi-asserted-by":"publisher","DOI":"10.1097\/00006231-198809000-00006"},{"key":"r082","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(93)90338-P"},{"key":"r083","first-page":"854","volume":"32","author":"Ravinsky E","year":"1988","journal-title":"Acta Cytol"},{"key":"r084","first-page":"48","volume":"33","author":"Tani E","year":"1989","journal-title":"Acta Cytol"},{"key":"r085","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.282.6260.258"},{"key":"r086","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2265.1993.tb02366.x"},{"key":"r087","doi-asserted-by":"publisher","DOI":"10.1001\/jama.258.2.209"},{"key":"r088","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1530\/acta.0.1060199","volume":"106","author":"Lazarus JH","year":"1984","journal-title":"Acta Endocrinol (Copenh)"},{"key":"r089","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2265.1981.tb00699.x"},{"key":"r090","unstructured":"Kurihara H, Sasaki J, Takamatsu M. Twenty cases with Hashimoto disease changing to Graves' disease. In: Nagataki S, Mori T, Torizuka K, eds. 80 Years of Hashimoto disease. Amsterdam: Elsevier Science, 1993:249-53."},{"key":"r091","first-page":"51","volume":"49","author":"Sugrue D","year":"1980","journal-title":"Q J Med"},{"key":"r092","doi-asserted-by":"publisher","DOI":"10.1172\/JCI109601"},{"key":"r093","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2265.1989.tb01244.x"},{"key":"r094","first-page":"1085","volume":"76","author":"Kato I","year":"1985","journal-title":"Jpn J Cancer Res"},{"key":"r095","doi-asserted-by":"publisher","DOI":"10.1089\/thy.1993.3.93"},{"key":"r096","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198503073121001"},{"key":"r097","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19860701)58:1<100::AID-CNCR2820580118>3.0.CO;2-1"},{"key":"r098","doi-asserted-by":"publisher","DOI":"10.1007\/BF00430248"},{"key":"r099","first-page":"333","volume":"14","author":"Oertel JE","year":"1987","journal-title":"Semin Oncol"},{"key":"r100","doi-asserted-by":"publisher","DOI":"10.1001\/jama.264.11.1422"},{"key":"r101","doi-asserted-by":"crossref","first-page":"837","DOI":"10.1016\/S0002-9378(12)90830-3","volume":"168","author":"Pratt D","year":"1993","journal-title":"Am J Obstet Gynecol"},{"key":"r102","doi-asserted-by":"publisher","DOI":"10.1055\/s-2007-999597"},{"key":"r103","first-page":"1","volume":"16","author":"Stagnaro-Green A","year":"1993","journal-title":"Thyroid Today"},{"key":"r104","doi-asserted-by":"publisher","DOI":"10.1210\/jcem-67-2-327"},{"key":"r105","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1016\/0002-9378(88)90522-4","volume":"159","author":"Hayslip CC","year":"1988","journal-title":"Am J Obstet Gynecol"},{"key":"r106","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.150.7.1397"},{"key":"r107","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2265.1990.tb00898.x"},{"key":"r108","doi-asserted-by":"publisher","DOI":"10.1210\/jcem-66-3-480"},{"key":"r109","doi-asserted-by":"crossref","first-page":"492","DOI":"10.7326\/0003-4819-119-6-199309150-00009","volume":"119","author":"Mandel SJ","year":"1993","journal-title":"Ann Intern Med"},{"key":"r110","doi-asserted-by":"crossref","first-page":"18","DOI":"10.7326\/0003-4819-101-1-18","volume":"101","author":"Cooper DS","year":"1984","journal-title":"Ann Intern Med"},{"key":"r111","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2265.1988.tb00250.x"},{"key":"r112","doi-asserted-by":"publisher","DOI":"10.1016\/0140-6736(90)92567-2"},{"key":"r113","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199202203260810"},{"key":"r114","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2265.1991.tb03528.x"},{"key":"r115","unstructured":"Kikuchi T, Yamaguchi Y, Kobayashi T, et al. Studies on thyroid volume during thyroid hormone therapy in patients with Hashimoto thyroiditis. In: Nagataki S, Mori T, Torizuka K, eds. 80 Years of Hashimoto disease. Amsterdam: Elsevier Science, 1993:201-3."},{"key":"r116","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1007\/BF03346932","volume":"9","author":"Chiovato L","year":"1986","journal-title":"J Endocrinol Invest"},{"key":"r117","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2265.1994.tb02494.x"}],"container-title":["New England Journal of Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.nejm.org\/doi\/pdf\/10.1056\/NEJM199607113350206","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,23]],"date-time":"2023-04-23T20:19:26Z","timestamp":1682281166000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.nejm.org\/doi\/abs\/10.1056\/NEJM199607113350206"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1996,7,11]]},"references-count":117,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1996,7,11]]}},"alternative-id":["10.1056\/NEJM199607113350206"],"URL":"https:\/\/doi.org\/10.1056\/nejm199607113350206","relation":{},"ISSN":["0028-4793","1533-4406"],"issn-type":[{"value":"0028-4793","type":"print"},{"value":"1533-4406","type":"electronic"}],"subject":[],"published":{"date-parts":[[1996,7,11]]}}}