{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T22:27:46Z","timestamp":1790634466772,"version":"4.1.0"},"reference-count":50,"publisher":"Massachusetts Medical Society","issue":"12","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["N Engl J Med"],"published-print":{"date-parts":[[1998,3,19]]},"DOI":"10.1056\/nejm199803193381203","type":"journal-article","created":{"date-parts":[[2002,7,27]],"date-time":"2002-07-27T12:53:28Z","timestamp":1027774408000},"page":"791-797","source":"Crossref","is-referenced-by-count":580,"title":["A Comparison of Sucralfate and Ranitidine for the Prevention of Upper Gastrointestinal Bleeding in Patients Requiring Mechanical Ventilation"],"prefix":"10.1056","volume":"338","author":[{"given":"Deborah","family":"Cook","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gordon","family":"Guyatt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John","family":"Marshall","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Leasa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hugh","family":"Fuller","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard","family":"Hall","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sharon","family":"Peters","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frank","family":"Rutledge","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lauren","family":"Griffith","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Allan","family":"McLellan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gordon","family":"Wood","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ann","family":"Kirby","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin","family":"Tweeddale","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joe","family":"Pagliarello","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard","family":"Johnston","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"150","reference":[{"key":"r001","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(85)90575-3"},{"key":"r002","doi-asserted-by":"publisher","DOI":"10.1097\/00003246-198709000-00003"},{"key":"r003","doi-asserted-by":"crossref","first-page":"562","DOI":"10.7326\/0003-4819-106-4-562","volume":"106","author":"Shuman RB","year":"1987","journal-title":"Ann Intern Med"},{"key":"r004","doi-asserted-by":"publisher","DOI":"10.1007\/BF01720905"},{"key":"r005","doi-asserted-by":"publisher","DOI":"10.1097\/00003246-199301000-00003"},{"key":"r006","doi-asserted-by":"publisher","DOI":"10.1007\/BF01720900"},{"key":"r007","first-page":"708","volume":"90","author":"Navab F","year":"1995","journal-title":"Am J Gastroenterol"},{"key":"r008","doi-asserted-by":"publisher","DOI":"10.1097\/00005373-197701000-00006"},{"key":"r009","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(84)90286-9"},{"key":"r010","doi-asserted-by":"publisher","DOI":"10.1097\/00003246-199201000-00013"},{"key":"r011","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199402103300601"},{"key":"r012","doi-asserted-by":"publisher","DOI":"10.1001\/jama.275.4.308"},{"key":"r013","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(78)92530-8"},{"key":"r014","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(82)90974-6"},{"key":"r015","first-page":"792","volume":"133","author":"Craven DE","year":"1986","journal-title":"Am Rev Respir Dis"},{"key":"r016","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198711263172204"},{"key":"r017","first-page":"704","volume":"37","author":"Laggner AN","year":"1988","journal-title":"Anaesthesist"},{"key":"r018","unstructured":"Prodhom G, Leuenberger PH, Blum AL, et al. Effect of stress ulcer prophylaxis on nosocomial pneumonia in ventilated patients: a randomized comparative study. In: Program and abstracts of the 31st Interscience Conference on Antimicrobial Agents and Chemotherapy, Chicago, September 29\u2013October 2, 1991. Washington, D.C.: American Society for Microbiology, 1991."},{"key":"r019","first-page":"S95","volume":"20","author":"Pickworth KK","year":"1992","journal-title":"Crit Care Med"},{"key":"r020","first-page":"S19","volume":"16","author":"Garcia-Labattut A","year":"1990","journal-title":"Intensive Care Med"},{"key":"r021","doi-asserted-by":"publisher","DOI":"10.1097\/00003246-199112000-00009"},{"key":"r022","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.147.12.2101"},{"key":"r023","doi-asserted-by":"crossref","first-page":"568","DOI":"10.7326\/0003-4819-121-8-199410150-00003","volume":"121","author":"Ben-Menachem T","year":"1994","journal-title":"Ann Intern Med"},{"key":"r024","doi-asserted-by":"crossref","first-page":"1353","DOI":"10.1001\/archsurg.1993.01420240061011","volume":"128","author":"Ryan P","year":"1993","journal-title":"Arch Surg"},{"key":"r025","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1001\/archsurg.1993.01420140062010","volume":"128","author":"Fabian TC","year":"1993","journal-title":"Arch Surg"},{"key":"r026","doi-asserted-by":"publisher","DOI":"10.1097\/00003246-199304001-00103"},{"key":"r027","doi-asserted-by":"publisher","DOI":"10.1007\/BF01701491"},{"key":"r028","doi-asserted-by":"crossref","first-page":"A93","DOI":"10.1097\/00003246-199501001-00142","volume":"23","author":"Thomason M","year":"1995","journal-title":"Crit Care Med"},{"key":"r029","doi-asserted-by":"publisher","DOI":"10.1097\/00003246-199107000-00011"},{"key":"r030","doi-asserted-by":"publisher","DOI":"10.1097\/00005373-199104000-00013"},{"key":"r031","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199402103300610"},{"key":"r032","doi-asserted-by":"publisher","DOI":"10.1001\/jama.273.5.408"},{"key":"r033","doi-asserted-by":"publisher","DOI":"10.1097\/00003246-198510000-00009"},{"key":"r034","doi-asserted-by":"publisher","DOI":"10.1097\/00003246-199510000-00007"},{"key":"r035","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1177\/088506669100600403","volume":"6","author":"Cook DJ","year":"1991","journal-title":"J Intensive Care Med"},{"key":"r036","doi-asserted-by":"crossref","first-page":"1058","DOI":"10.1164\/ajrccm\/139.4.1058","volume":"139","year":"1989","journal-title":"Am Rev Respir Dis"},{"key":"r037","first-page":"337","volume":"119","author":"Wimberley N","year":"1979","journal-title":"Am Rev Respir Dis"},{"key":"r038","doi-asserted-by":"publisher","DOI":"10.1378\/chest.102.5_Supplement_1.557S"},{"key":"r039","doi-asserted-by":"crossref","first-page":"1121","DOI":"10.1164\/ajrccm\/143.5_Pt_1.1121","volume":"143","author":"Pugin J","year":"1991","journal-title":"Am Rev Respir Dis"},{"key":"r040","doi-asserted-by":"publisher","DOI":"10.1378\/chest.102.5_Supplement_1.553S"},{"key":"r041","unstructured":"Fleiss JL. Statistical methods for rates and proportions. 2nd ed. New York: John Wiley, 1981."},{"key":"r042","unstructured":"Aitkin M, Anderson D, Francis B, Hinde J. Statistical modelling in GLIM. Oxford, England: Clarendon Press, 1989."},{"key":"r043","first-page":"S19","volume":"3","author":"Labattut AG","year":"1992","journal-title":"Clin Intensive Care"},{"key":"r044","doi-asserted-by":"publisher","DOI":"10.1097\/00003246-199422120-00010"},{"key":"r045","doi-asserted-by":"publisher","DOI":"10.2165\/00019053-199609050-00008"},{"key":"r046","doi-asserted-by":"publisher","DOI":"10.1097\/00003246-199602000-00026"},{"key":"r047","doi-asserted-by":"publisher","DOI":"10.1097\/00003246-199710000-00017"},{"key":"r048","doi-asserted-by":"publisher","DOI":"10.1080\/714028943"},{"key":"r049","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(93)90060-3"},{"key":"r050","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1164\/ajrccm.154.1.8680705","volume":"154","author":"Papazian L","year":"1996","journal-title":"Am J Respir Crit Care Med"}],"container-title":["New England Journal of Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.nejm.org\/doi\/pdf\/10.1056\/NEJM199803193381203","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,6,15]],"date-time":"2017-06-15T10:48:13Z","timestamp":1497523693000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.nejm.org\/doi\/abs\/10.1056\/NEJM199803193381203"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1998,3,19]]},"references-count":50,"journal-issue":{"issue":"12","published-print":{"date-parts":[[1998,3,19]]}},"alternative-id":["10.1056\/NEJM199803193381203"],"URL":"https:\/\/doi.org\/10.1056\/nejm199803193381203","relation":{},"ISSN":["0028-4793","1533-4406"],"issn-type":[{"value":"0028-4793","type":"print"},{"value":"1533-4406","type":"electronic"}],"subject":[],"published":{"date-parts":[[1998,3,19]]}}}