{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,14]],"date-time":"2026-02-14T03:30:32Z","timestamp":1771039832053,"version":"3.50.1"},"reference-count":5,"publisher":"Massachusetts Medical Society","issue":"14","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["N Engl J Med"],"published-print":{"date-parts":[[2022,10,6]]},"DOI":"10.1056\/nejmcibr2209405","type":"journal-article","created":{"date-parts":[[2022,9,28]],"date-time":"2022-09-28T16:00:13Z","timestamp":1664380813000},"page":"1322-1324","source":"Crossref","is-referenced-by-count":10,"title":["Circulating Cell-free DNA and Screening for Trisomies"],"prefix":"10.1056","volume":"387","author":[{"given":"Mary E.","family":"Norton","sequence":"first","affiliation":[{"name":"From the Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California, San Francisco, San Francisco."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"150","reference":[{"key":"e_1_3_4_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(97)02174-0"},{"key":"e_1_3_4_3_2","doi-asserted-by":"publisher","DOI":"10.1177\/096914139700400402"},{"key":"e_1_3_4_4_2","first-page":"241","article-title":"Les acides nucl\u00e9iques du plasma sanguin chez l\u2019homme.","volume":"142","author":"Mandel P","year":"1948","unstructured":"Mandel P, Metais P. Les acides nucl\u00e9iques du plasma sanguin chez l\u2019homme. C R Seances Soc Biol Fil 1948;142:241-243.18875018","journal-title":"C R Seances Soc Biol Fil"},{"key":"e_1_3_4_5_2","doi-asserted-by":"publisher","DOI":"10.1111\/1471-0528.14050"},{"key":"e_1_3_4_6_2","doi-asserted-by":"publisher","DOI":"10.1002\/pd.4601"}],"container-title":["New England Journal of Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.nejm.org\/doi\/pdf\/10.1056\/NEJMcibr2209405","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,6,11]],"date-time":"2025-06-11T23:09:16Z","timestamp":1749683356000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.nejm.org\/doi\/10.1056\/NEJMcibr2209405"}},"subtitle":[],"editor":[{"given":"Elizabeth G.","family":"Phimister","sequence":"additional","affiliation":[],"role":[{"role":"editor","vocabulary":"crossref"}]}],"short-title":[],"issued":{"date-parts":[[2022,10,6]]},"references-count":5,"journal-issue":{"issue":"14","published-print":{"date-parts":[[2022,10,6]]}},"alternative-id":["10.1056\/NEJMcibr2209405"],"URL":"https:\/\/doi.org\/10.1056\/nejmcibr2209405","relation":{},"ISSN":["0028-4793","1533-4406"],"issn-type":[{"value":"0028-4793","type":"print"},{"value":"1533-4406","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,10,6]]}}}