{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T04:15:36Z","timestamp":1791173736919,"version":"4.1.0"},"reference-count":39,"publisher":"Massachusetts Medical Society","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["N Engl J Med"],"published-print":{"date-parts":[[2013,7,11]]},"DOI":"10.1056\/nejmcpc1302332","type":"journal-article","created":{"date-parts":[[2013,7,10]],"date-time":"2013-07-10T21:02:16Z","timestamp":1373490136000},"page":"173-183","source":"Crossref","is-referenced-by-count":29,"title":["Case 21-2013"],"prefix":"10.1056","volume":"369","author":[{"given":"Ryan J.","family":"Sullivan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Donald P.","family":"Lawrence","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer A.","family":"Wargo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kevin S.","family":"Oh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R. Gilberto","family":"Gonzalez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adriano","family":"Piris","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"150","reference":[{"key":"r001","doi-asserted-by":"publisher","DOI":"10.1038\/nature08833"},{"key":"r002","doi-asserted-by":"publisher","DOI":"10.1038\/nature08902"},{"key":"r003","doi-asserted-by":"publisher","DOI":"10.1038\/nature00766"},{"key":"r004","first-page":"31","volume":"8","author":"Flaherty K","year":"2010","journal-title":"Clin Adv Hematol Oncol"},{"key":"r005","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-10-0174"},{"key":"r006","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1002011"},{"key":"r007","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1103782"},{"key":"r008","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1210093"},{"key":"r009","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(12)60868-X"},{"key":"r010","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1003466"},{"key":"r011","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1104621"},{"key":"r012","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1203421"},{"key":"r013","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1200690"},{"key":"r014","doi-asserted-by":"publisher","first-page":"2105","DOI":"10.1200\/JCO.1999.17.7.2105","volume":"17","author":"Atkins MB","year":"1999","journal-title":"J Clin Oncol"},{"key":"r015","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2012.41.6750"},{"key":"r016","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1112302"},{"key":"r017","doi-asserted-by":"crossref","first-page":"8569","DOI":"10.1200\/jco.2012.30.15_suppl.8569","volume":"30","author":"Ackerman A","year":"2012","journal-title":"J Clin Oncol"},{"key":"r018","doi-asserted-by":"publisher","DOI":"10.1186\/1479-5876-10-107"},{"key":"r019","doi-asserted-by":"publisher","DOI":"10.1097\/CJI.0b013e3182742c27"},{"key":"r020","doi-asserted-by":"publisher","DOI":"10.1097\/01.cji.0000211334.06762.89"},{"key":"r021","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.25634"},{"key":"r022","doi-asserted-by":"publisher","DOI":"10.1016\/S0360-3016(99)00507-6"},{"key":"r023","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2010.30.1655"},{"key":"r024","doi-asserted-by":"publisher","DOI":"10.1001\/jama.295.21.2483"},{"key":"r025","doi-asserted-by":"publisher","DOI":"10.1001\/jama.280.17.1485"},{"key":"r026","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(12)60398-5"},{"key":"r027","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(12)70431-X"},{"key":"r028","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(12)70090-6"},{"key":"r029","doi-asserted-by":"publisher","DOI":"10.1259\/0007-1285-26-305-234"},{"key":"r030","doi-asserted-by":"publisher","DOI":"10.1259\/0007-1285-48-574-863"},{"key":"r031","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1112824"},{"key":"r032","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20062056"},{"key":"r033","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-10-0118"},{"key":"r034","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-12-1630"},{"key":"r035","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-11-2479"},{"key":"r036","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-12-1632"},{"key":"r037","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-12-1626"},{"key":"r038","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-11-2837"},{"key":"r039","doi-asserted-by":"publisher","DOI":"10.1007\/s00262-012-1227-3"}],"container-title":["New England Journal of Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.nejm.org\/doi\/pdf\/10.1056\/NEJMcpc1302332","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,7,30]],"date-time":"2020-07-30T10:48:06Z","timestamp":1596106086000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.nejm.org\/doi\/10.1056\/NEJMcpc1302332"}},"subtitle":["A 68-Year-Old Man with Metastatic Melanoma"],"editor":[{"given":"Richard C.","family":"Cabot","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]},{"given":"Eric S.","family":"Rosenberg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]},{"given":"Nancy Lee","family":"Harris","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]},{"given":"Jo-Anne O.","family":"Shepard","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]},{"given":"Alice M.","family":"Cort","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]},{"given":"Sally H.","family":"Ebeling","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]},{"given":"Emily K.","family":"McDonald","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2013,7,11]]},"references-count":39,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2013,7,11]]}},"alternative-id":["10.1056\/NEJMcpc1302332"],"URL":"https:\/\/doi.org\/10.1056\/nejmcpc1302332","relation":{},"ISSN":["0028-4793","1533-4406"],"issn-type":[{"value":"0028-4793","type":"print"},{"value":"1533-4406","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,7,11]]}}}