{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T20:54:23Z","timestamp":1790715263133,"version":"4.1.0"},"reference-count":27,"publisher":"Massachusetts Medical Society","issue":"20","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["N Engl J Med"],"published-print":{"date-parts":[[2018,11,15]]},"DOI":"10.1056\/nejmcpc1616400","type":"journal-article","created":{"date-parts":[[2018,11,14]],"date-time":"2018-11-14T22:05:06Z","timestamp":1542233106000},"page":"1946-1953","source":"Crossref","is-referenced-by-count":9,"title":["Case 35-2018: A 68-Year-Old Woman with Back Pain and a Remote History of Breast Cancer"],"prefix":"10.1056","volume":"379","author":[{"given":"Aditya","family":"Bardia","sequence":"first","affiliation":[{"name":"From the Departments of Medicine (A.B.), Radiology (M.D.H.), and Pathology (E.F.B., V.N.), Massachusetts General Hospital, and the Departments of Medicine (A.B.), Radiology (M.D.H.), and Pathology (E.F.B., V.N.), Harvard Medical School \u2014 both in Boston."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meline D.","family":"Hovnanian","sequence":"additional","affiliation":[{"name":"From the Departments of Medicine (A.B.), Radiology (M.D.H.), and Pathology (E.F.B., V.N.), Massachusetts General Hospital, and the Departments of Medicine (A.B.), Radiology (M.D.H.), and Pathology (E.F.B., V.N.), Harvard Medical School \u2014 both in Boston."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elena F.","family":"Brachtel","sequence":"additional","affiliation":[{"name":"From the Departments of Medicine (A.B.), Radiology (M.D.H.), and Pathology (E.F.B., V.N.), Massachusetts General Hospital, and the Departments of Medicine (A.B.), Radiology (M.D.H.), and Pathology (E.F.B., V.N.), Harvard Medical School \u2014 both in Boston."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Valentina","family":"Nardi","sequence":"additional","affiliation":[{"name":"From the Departments of Medicine (A.B.), Radiology (M.D.H.), and Pathology (E.F.B., V.N.), Massachusetts General Hospital, and the Departments of Medicine (A.B.), Radiology (M.D.H.), and Pathology (E.F.B., V.N.), Harvard Medical School \u2014 both in Boston."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"150","reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199605233342102"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2011.90"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.6004\/jnccn.2016.0037"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2013.54.2258"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(10)70257-6"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1701830"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(12)61963-1"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1604700"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2010.34.4010"},{"key":"e_1_3_3_11_2","doi-asserted-by":"crossref","unstructured":"Gnant M Steger G Greil R et al. A prospective randomized multi-center phase-III trial of additional 2 versus additional 5 years of anastrozole after initial 5 years of adjuvant endocrine therapy \u2014 results from 3 484 postmenopausal women in the ABCSG-16 trial. Presented at the San Antonio Breast Cancer Symposium 2017 San Antonio TX December 5\u20139 2017:GS3-01-GS3-01. abstract.","DOI":"10.1158\/1538-7445.SABCS17-GS3-01"},{"key":"e_1_3_3_12_2","doi-asserted-by":"crossref","unstructured":"Mamounas EP Bandos H Lembersky BC et al. A randomized double-blinded placebo-controlled clinical trial of extended adjuvant endocrine therapy (tx) with letrozole (L) in postmenopausal women with hormone-receptor (+) breast cancer (BC) who have completed previous adjuvant tx with an aromatase inhibitor (AI): results from NRG Oncology\/NSABP B-42. Presented at the San Antonio Breast Cancer Symposium 2016 San Antonio TX December 6\u201310 2016:S1-05-S1-05. abstract.","DOI":"10.1158\/1538-7445.SABCS16-S1-05"},{"key":"e_1_3_3_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(17)30600-9"},{"key":"e_1_3_3_14_2","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2003.07.071"},{"key":"e_1_3_3_15_2","volume-title":"WHO classification of tumours of the breast. 4th ed","author":"Lakhani SR","year":"2012","unstructured":"Lakhani SR, Ellis IO, Schnitt SJ, Tan PH, van de Vijver MJ. WHO classification of tumours of the breast. 4th ed. Lyon, France: International Agency for Research on Cancer, 2012."},{"key":"e_1_3_3_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(13)70387-5"},{"key":"e_1_3_3_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(14)71159-3"},{"key":"e_1_3_3_18_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1607303"},{"key":"e_1_3_3_19_2","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2017.75.6155"},{"key":"e_1_3_3_20_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1609709"},{"key":"e_1_3_3_21_2","doi-asserted-by":"publisher","DOI":"10.1038\/ng.2823"},{"key":"e_1_3_3_22_2","doi-asserted-by":"publisher","DOI":"10.1038\/ng.2822"},{"key":"e_1_3_3_23_2","doi-asserted-by":"publisher","DOI":"10.1001\/jamaoncol.2016.1279"},{"key":"e_1_3_3_24_2","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-15-0943"},{"key":"e_1_3_3_25_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.1253533"},{"key":"e_1_3_3_26_2","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2016.67.3061"},{"key":"e_1_3_3_27_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1113205"},{"key":"e_1_3_3_28_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1804710"}],"container-title":["New England Journal of Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.nejm.org\/doi\/pdf\/10.1056\/NEJMcpc1616400","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,3,27]],"date-time":"2024-03-27T00:25:10Z","timestamp":1711499110000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.nejm.org\/doi\/10.1056\/NEJMcpc1616400"}},"subtitle":[],"editor":[{"given":"Richard C.","family":"Cabot","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]},{"given":"Eric S.","family":"Rosenberg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]},{"given":"Virginia M.","family":"Pierce","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]},{"given":"David M.","family":"Dudzinski","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]},{"given":"Meridale V.","family":"Baggett","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]},{"given":"Dennis C.","family":"Sgroi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]},{"given":"Jo-Anne O.","family":"Shepard","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]},{"given":"Alyssa Y.","family":"Castillo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]},{"given":"Emily K.","family":"McDonald","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]},{"given":"Sally H.","family":"Ebeling","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2018,11,15]]},"references-count":27,"journal-issue":{"issue":"20","published-print":{"date-parts":[[2018,11,15]]}},"alternative-id":["10.1056\/NEJMcpc1616400"],"URL":"https:\/\/doi.org\/10.1056\/nejmcpc1616400","relation":{},"ISSN":["0028-4793","1533-4406"],"issn-type":[{"value":"0028-4793","type":"print"},{"value":"1533-4406","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,11,15]]}}}