{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,2]],"date-time":"2025-11-02T16:27:15Z","timestamp":1762100835327},"reference-count":17,"publisher":"Massachusetts Medical Society","issue":"26","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["N Engl J Med"],"published-print":{"date-parts":[[2008,6,26]]},"DOI":"10.1056\/nejme0804008","type":"journal-article","created":{"date-parts":[[2008,6,25]],"date-time":"2008-06-25T21:23:02Z","timestamp":1214428982000},"page":"2829-2831","source":"Crossref","is-referenced-by-count":15,"title":["A Small Molecule for a Large Disease"],"prefix":"10.1056","volume":"358","author":[{"given":"Reed E.","family":"Pyeritz","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"150","reference":[{"key":"r001","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM197904053001406"},{"key":"r002","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9149(00)80066-1"},{"key":"r003","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199904293401702"},{"key":"r004","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199405123301902"},{"key":"r005","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.107.693523"},{"key":"r006","unstructured":"Pyeritz RE. Marfan syndrome and related disorders. In: Rimoin DL, Conner JM, Pyeritz RE, Korf BR, eds. Principles and practice of medical genetics. 5th ed. Philadelphia: Churchill Livingstone, 2007:3579-24."},{"key":"r007","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1002\/ajmg.a.30525","volume":"134","author":"Foran JR","year":"2005","journal-title":"Am J Med Genet A"},{"key":"r008","doi-asserted-by":"publisher","DOI":"10.1097\/GIM.0b013e3180423cb3"},{"key":"r009","doi-asserted-by":"publisher","DOI":"10.1038\/352337a0"},{"key":"r010","doi-asserted-by":"publisher","DOI":"10.1038\/ng1116"},{"key":"r011","doi-asserted-by":"crossref","first-page":"1586","DOI":"10.1172\/JCI200422715","volume":"114","author":"Ng CM","year":"2004","journal-title":"J Clin Invest"},{"key":"r012","doi-asserted-by":"publisher","DOI":"10.1126\/science.1124287"},{"key":"r013","doi-asserted-by":"publisher","DOI":"10.1097\/01.ASN.0000093460.24823.5B"},{"key":"r014","doi-asserted-by":"publisher","DOI":"10.1038\/nm1536"},{"key":"r015","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa0706585"},{"key":"r016","doi-asserted-by":"publisher","DOI":"10.1016\/j.ahj.2007.06.024"},{"key":"L1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa0706585"}],"container-title":["New England Journal of Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.nejm.org\/doi\/pdf\/10.1056\/NEJMe0804008","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,12]],"date-time":"2019-05-12T09:59:03Z","timestamp":1557655143000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.nejm.org\/doi\/abs\/10.1056\/NEJMe0804008"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,6,26]]},"references-count":17,"journal-issue":{"issue":"26","published-print":{"date-parts":[[2008,6,26]]}},"alternative-id":["10.1056\/NEJMe0804008"],"URL":"https:\/\/doi.org\/10.1056\/nejme0804008","relation":{},"ISSN":["0028-4793","1533-4406"],"issn-type":[{"value":"0028-4793","type":"print"},{"value":"1533-4406","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,6,26]]}}}