{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T18:00:13Z","timestamp":1792605613173,"version":"4.5.0"},"reference-count":30,"publisher":"Massachusetts Medical Society","issue":"24","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["N Engl J Med"],"published-print":{"date-parts":[[2001,12,13]]},"DOI":"10.1056\/nejmoa011503","type":"journal-article","created":{"date-parts":[[2002,7,27]],"date-time":"2002-07-27T08:57:19Z","timestamp":1027760239000},"page":"1740-1746","source":"Crossref","is-referenced-by-count":1095,"title":["Recurrent Cerebrovascular Events Associated with Patent Foramen Ovale, Atrial Septal Aneurysm, or Both"],"prefix":"10.1056","volume":"345","author":[{"given":"Jean-Louis","family":"Mas","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Caroline","family":"Arquizan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Catherine","family":"Lamy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mathieu","family":"Zuber","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laure","family":"Cabanes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Genevi\u00e8ve","family":"Derumeaux","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jo\u00ebl","family":"Coste","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"150","reference":[{"key":"r001","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198805053181802"},{"key":"r002","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(88)92944-3"},{"key":"r003","doi-asserted-by":"crossref","first-page":"461","DOI":"10.7326\/0003-4819-117-6-461","volume":"117","author":"Di Tullio M","year":"1992","journal-title":"Ann Intern Med"},{"key":"r004","doi-asserted-by":"publisher","DOI":"10.1016\/0735-1097(91)90539-L"},{"key":"r005","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.24.12.1865"},{"key":"r006","doi-asserted-by":"crossref","first-page":"1172","DOI":"10.1212\/WNL.55.8.1172","volume":"55","author":"Overell JR","year":"2000","journal-title":"Neurology"},{"key":"r007","doi-asserted-by":"crossref","first-page":"446","DOI":"10.1093\/oxfordjournals.eurheartj.a060524","volume":"15","author":"Mas JL","year":"1994","journal-title":"Eur Heart J"},{"key":"r008","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.25.4.782"},{"key":"r009","doi-asserted-by":"publisher","DOI":"10.1016\/0002-8703(95)90212-0"},{"key":"r010","doi-asserted-by":"publisher","DOI":"10.1016\/0735-1097(95)00288-9"},{"key":"r011","doi-asserted-by":"crossref","first-page":"1301","DOI":"10.1212\/WNL.46.5.1301","volume":"46","author":"Bogousslavsky J","year":"1996","journal-title":"Neurology"},{"key":"r012","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-8703(96)90065-4"},{"key":"r013","first-page":"57","volume":"15","author":"Cujec B","year":"1999","journal-title":"Can J Cardiol"},{"key":"r014","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.31.10.2407"},{"key":"r015","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.19.5.604"},{"key":"r016","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.24.1.35"},{"key":"r017","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-2982.1991.tb00022.x"},{"key":"r019","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.21.4.637"},{"key":"r020","unstructured":"Armitage P, Berry G. Statistical methods in medical research. 2nd ed. Oxford, England: Blackwell Scientific, 1987."},{"key":"r021","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.25.3.582"},{"key":"r022","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.29.7.1322"},{"key":"r023","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.29.5.944"},{"key":"r024","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9343(00)00530-1"},{"key":"r025","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.24.1.31"},{"key":"r026","first-page":"62","volume":"102","author":"Silver MD","year":"1978","journal-title":"Arch Pathol Lab Med"},{"key":"r027","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(10)80354-7"},{"key":"r028","doi-asserted-by":"crossref","first-page":"2785","DOI":"10.1161\/01.CIR.91.11.2785","volume":"91","author":"Mugge A","year":"1995","journal-title":"Circulation"},{"key":"r029","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.31.2.398"},{"key":"r030","doi-asserted-by":"crossref","first-page":"1902","DOI":"10.1161\/01.CIR.86.6.1902","volume":"86","author":"Bridges ND","year":"1992","journal-title":"Circulation"},{"key":"r031","doi-asserted-by":"crossref","first-page":"1162","DOI":"10.1212\/WNL.47.5.1162","volume":"47","author":"Devuyst G","year":"1996","journal-title":"Neurology"}],"container-title":["New England Journal of Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.nejm.org\/doi\/pdf\/10.1056\/NEJMoa011503","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,12,16]],"date-time":"2017-12-16T22:30:07Z","timestamp":1513463407000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.nejm.org\/doi\/abs\/10.1056\/NEJMoa011503"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2001,12,13]]},"references-count":30,"journal-issue":{"issue":"24","published-print":{"date-parts":[[2001,12,13]]}},"alternative-id":["10.1056\/NEJMoa011503"],"URL":"https:\/\/doi.org\/10.1056\/nejmoa011503","relation":{},"ISSN":["0028-4793","1533-4406"],"issn-type":[{"value":"0028-4793","type":"print"},{"value":"1533-4406","type":"electronic"}],"subject":[],"published":{"date-parts":[[2001,12,13]]}}}