{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T14:43:28Z","timestamp":1791902608559,"version":"4.3.4"},"reference-count":28,"publisher":"Massachusetts Medical Society","issue":"26","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["N Engl J Med"],"published-print":{"date-parts":[[2002,12,26]]},"DOI":"10.1056\/nejmoa021907","type":"journal-article","created":{"date-parts":[[2002,12,25]],"date-time":"2002-12-25T17:21:56Z","timestamp":1040836916000},"page":"2104-2110","source":"Crossref","is-referenced-by-count":439,"title":["Celecoxib versus Diclofenac and Omeprazole in Reducing the Risk of Recurrent Ulcer Bleeding in Patients with Arthritis"],"prefix":"10.1056","volume":"347","author":[{"given":"Francis K.L.","family":"Chan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lawrence C.T.","family":"Hung","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bing Y.","family":"Suen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Justin C.Y.","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kenneth C.","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vincent K.S.","family":"Leung","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aric J.","family":"Hui","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ka F.","family":"To","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wai K.","family":"Leung","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vincent W.S.","family":"Wong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.C. Sydney","family":"Chung","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joseph J.Y.","family":"Sung","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"150","reference":[{"key":"r001","doi-asserted-by":"publisher","DOI":"10.1001\/jama.282.20.1961"},{"key":"r002","first-page":"18","volume":"26","author":"Singh G","year":"1999","journal-title":"J Rheumatol"},{"key":"r003","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(94)91843-0"},{"key":"r004","doi-asserted-by":"crossref","first-page":"787","DOI":"10.7326\/0003-4819-115-10-787","volume":"115","author":"Gabriel SE","year":"1991","journal-title":"Ann Intern Med"},{"key":"r005","doi-asserted-by":"crossref","first-page":"257","DOI":"10.7326\/0003-4819-119-4-199308150-00001","volume":"119","author":"Graham DY","year":"1993","journal-title":"Ann Intern Med"},{"key":"r006","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.162.2.169"},{"key":"r007","doi-asserted-by":"crossref","first-page":"241","DOI":"10.7326\/0003-4819-123-4-199508150-00001","volume":"123","author":"Silverstein FE","year":"1995","journal-title":"Ann Intern Med"},{"key":"r008","doi-asserted-by":"publisher","DOI":"10.1097\/00001648-199905000-00006"},{"key":"r009","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM200103293441304"},{"key":"r010","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199906173402407"},{"key":"r011","doi-asserted-by":"publisher","DOI":"10.1053\/gast.2001.21907"},{"key":"r012","doi-asserted-by":"publisher","DOI":"10.1016\/S0016-5085(99)70334-3"},{"key":"r013","doi-asserted-by":"publisher","DOI":"10.1001\/jama.282.20.1921"},{"key":"r014","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(99)02332-6"},{"key":"r015","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM200011233432103"},{"key":"r016","doi-asserted-by":"publisher","DOI":"10.1001\/jama.284.10.1247"},{"key":"r017","doi-asserted-by":"publisher","DOI":"10.1002\/1529-0131(200009)43:9<1905::AID-ANR1>3.0.CO;2-P"},{"key":"r018","doi-asserted-by":"publisher","DOI":"10.1002\/sim.4780141409"},{"key":"r019","doi-asserted-by":"publisher","DOI":"10.1038\/bjc.1976.220"},{"key":"r020","first-page":"A","volume":"120","author":"Chan FKL","year":"2001","journal-title":"Gastroenterology"},{"key":"r021","doi-asserted-by":"crossref","unstructured":"Altman DG. Practical statistics for medical research. London: Chapman & Hall, 1991.","DOI":"10.1201\/9780429258589"},{"key":"r022","doi-asserted-by":"publisher","DOI":"10.2307\/2281868"},{"key":"r023","unstructured":"Statistical reviewer briefing document for the Advisory Committee. Rockville, Md.: Food and Drug Administration, 2000. (Accessed November 4, 2002, at http:\/\/www.fda.gov\/ohrms\/dockets\/ac\/01\/briefing\/3677b1_04_stats.doc.)"},{"key":"r024","first-page":"2399","volume":"286","author":"Silverstein F","year":"2001","journal-title":"JAMA"},{"key":"r025","doi-asserted-by":"crossref","first-page":"1","DOI":"10.7326\/0003-4819-133-1-200007040-00002","volume":"133","author":"Swan SK","year":"2000","journal-title":"Ann Intern Med"},{"key":"r026","doi-asserted-by":"publisher","DOI":"10.1016\/S0009-9236(99)70056-1"},{"key":"r027","doi-asserted-by":"publisher","DOI":"10.1053\/gast.1997.v112.pm9024292"},{"key":"r028","first-page":"1383","volume":"286","author":"Shigeta J","year":"1998","journal-title":"J Pharmacol Exp Ther"}],"container-title":["New England Journal of Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.nejm.org\/doi\/pdf\/10.1056\/NEJMoa021907","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,6,2]],"date-time":"2021-06-02T08:17:21Z","timestamp":1622621841000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.nejm.org\/doi\/abs\/10.1056\/NEJMoa021907"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2002,12,26]]},"references-count":28,"journal-issue":{"issue":"26","published-print":{"date-parts":[[2002,12,26]]}},"alternative-id":["10.1056\/NEJMoa021907"],"URL":"https:\/\/doi.org\/10.1056\/nejmoa021907","relation":{},"ISSN":["0028-4793","1533-4406"],"issn-type":[{"value":"0028-4793","type":"print"},{"value":"1533-4406","type":"electronic"}],"subject":[],"published":{"date-parts":[[2002,12,26]]}}}