{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T15:33:18Z","timestamp":1791214398198,"version":"4.1.0"},"reference-count":32,"publisher":"Massachusetts Medical Society","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["N Engl J Med"],"published-print":{"date-parts":[[2005,8,4]]},"DOI":"10.1056\/nejmoa041292","type":"journal-article","created":{"date-parts":[[2005,8,3]],"date-time":"2005-08-03T21:29:30Z","timestamp":1123104570000},"page":"476-486","source":"Crossref","is-referenced-by-count":314,"title":["Modafinil for Excessive Sleepiness Associated with Shift-Work Sleep Disorder"],"prefix":"10.1056","volume":"353","author":[{"given":"Charles A.","family":"Czeisler","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James K.","family":"Walsh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Roth","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rod J","family":"Hughes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kenneth P.","family":"Wright","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lilliam","family":"Kingsbury","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sanjay","family":"Arora","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jonathan R.L.","family":"Schwartz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gwendolyn E.","family":"Niebler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David F.","family":"Dinges","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"150","reference":[{"key":"r001","first-page":"33","volume":"123","author":"Beers TM","year":"2000","journal-title":"Monthly Labor Rev"},{"key":"r002","doi-asserted-by":"publisher","DOI":"10.1093\/occmed\/kqg046"},{"key":"r003","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3999(02)00438-5"},{"key":"r004","unstructured":"Diagnostic and statistical manual of mental disorders, 4th ed. Washington, D.C.: American Psychiatric Association, 2000."},{"key":"r006","doi-asserted-by":"crossref","first-page":"1453","DOI":"10.1093\/sleep\/27.8.1453","volume":"27","author":"Drake CL","year":"2004","journal-title":"Sleep"},{"key":"r007","doi-asserted-by":"publisher","DOI":"10.1093\/occmed\/kqg048"},{"key":"r008","doi-asserted-by":"crossref","first-page":"1166","DOI":"10.1212\/WNL.54.5.1166","volume":"54","year":"2000","journal-title":"Neurology"},{"key":"r009","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410430115"},{"key":"r010","doi-asserted-by":"crossref","first-page":"1675","DOI":"10.1164\/ajrccm.164.9.2103032","volume":"164","author":"Pack AI","year":"2001","journal-title":"Am J Respir Crit Care Med"},{"key":"r011","doi-asserted-by":"crossref","first-page":"464","DOI":"10.1093\/sleep\/28.4.464","volume":"28","author":"Black JE","year":"2005","journal-title":"Sleep"},{"key":"r012","doi-asserted-by":"crossref","unstructured":"Guy W. ECDEU assessment manual for psychopharmacology. Rockville, Md.: National Institute of Mental Health, 1976.","DOI":"10.1037\/e591322011-001"},{"key":"r013","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1093\/sleep\/9.4.519","volume":"9","author":"Carskadon MA","year":"1986","journal-title":"Sleep"},{"key":"r014","doi-asserted-by":"publisher","DOI":"10.1016\/S0149-7634(87)80016-7"},{"key":"r015","unstructured":"Dorrian J, Rogers NL, Dinges DF. Psychomotor vigilance performance: neurocognitive assay sensitive to sleep loss. In: Kushida CA, ed. Sleep deprivation: clinical issues, pharmacology and sleep loss effects. New York: Marcel Dekker, 2005:39-70."},{"key":"r016","doi-asserted-by":"crossref","first-page":"S95","DOI":"10.1093\/sleep\/5.S2.S95","volume":"5","author":"Akerstedt T","year":"1982","journal-title":"Sleep"},{"key":"r017","unstructured":"Mitler MM, Carskadon MA, Hirshkowitz M. Evaluating sleepiness. In: Kryger MH, Roth T, Dement WC, eds. Principles and practice of sleep medicine. 3rd ed. Philadelphia: W.B. Saunders, 2000:1251-7."},{"key":"r018","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.201530198"},{"key":"r019","doi-asserted-by":"publisher","DOI":"10.1097\/00004691-199601000-00003"},{"key":"r020","doi-asserted-by":"publisher","DOI":"10.2165\/00023210-200115040-00005"},{"key":"r021","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199709113371106"},{"key":"r022","doi-asserted-by":"crossref","first-page":"R280","DOI":"10.1152\/ajpregu.00197.2002","volume":"284","author":"Leproult R","year":"2003","journal-title":"Am J Physiol Regul Integr Comp Physiol"},{"key":"r023","first-page":"423","volume":"27","author":"Van Dongen HPA","year":"2004","journal-title":"Sleep"},{"key":"r024","first-page":"9","volume":"28","author":"Akerstedt T","year":"2005","journal-title":"Sleep"},{"key":"r025","doi-asserted-by":"publisher","DOI":"10.1007\/s00420-003-0482-1"},{"key":"r026","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1093\/sleep\/26.2.117","volume":"26","author":"Van Dongen HP","year":"2003","journal-title":"Sleep"},{"key":"r027","first-page":"267","volume":"20","author":"Dinges DF","year":"1997","journal-title":"Sleep"},{"key":"r028","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-199910000-00019"},{"key":"r029","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2869.2003.00337.x"},{"key":"r030","first-page":"253","volume":"139","author":"Doran SM","year":"2001","journal-title":"Arch Ital Biol"},{"key":"r031","doi-asserted-by":"publisher","DOI":"10.1016\/S0166-2236(00)02002-6"},{"key":"r032","doi-asserted-by":"publisher","DOI":"10.1007\/BF02244139"},{"key":"r033","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1093\/sleep\/18.1.22","volume":"18","author":"Muehlbach MJ","year":"1995","journal-title":"Sleep"}],"container-title":["New England Journal of Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.nejm.org\/doi\/pdf\/10.1056\/NEJMoa041292","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,4,8]],"date-time":"2020-04-08T16:43:52Z","timestamp":1586364232000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.nejm.org\/doi\/abs\/10.1056\/NEJMoa041292"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,8,4]]},"references-count":32,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2005,8,4]]}},"alternative-id":["10.1056\/NEJMoa041292"],"URL":"https:\/\/doi.org\/10.1056\/nejmoa041292","relation":{},"ISSN":["0028-4793","1533-4406"],"issn-type":[{"value":"0028-4793","type":"print"},{"value":"1533-4406","type":"electronic"}],"subject":[],"published":{"date-parts":[[2005,8,4]]}}}