{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T00:27:51Z","timestamp":1791160071734,"version":"4.1.0"},"reference-count":42,"publisher":"Massachusetts Medical Society","issue":"13","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["N Engl J Med"],"published-print":{"date-parts":[[2012,3,29]]},"DOI":"10.1056\/nejmoa1110294","type":"journal-article","created":{"date-parts":[[2012,3,28]],"date-time":"2012-03-28T21:02:02Z","timestamp":1332968522000},"page":"1209-1217","source":"Crossref","is-referenced-by-count":254,"title":["Lifestyle Change and Mobility in Obese Adults with Type 2 Diabetes"],"prefix":"10.1056","volume":"366","author":[{"given":"W. Jack","family":"Rejeski","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edward H.","family":"Ip","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alain G.","family":"Bertoni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"George A.","family":"Bray","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gina","family":"Evans","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edward W.","family":"Gregg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qiang","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"150","reference":[{"key":"r001","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-140-11-200406010-00035"},{"key":"r002","doi-asserted-by":"publisher","DOI":"10.1186\/1478-7954-8-29"},{"key":"r003","doi-asserted-by":"publisher","DOI":"10.2337\/diacare.27.5.1047"},{"key":"r005","doi-asserted-by":"publisher","DOI":"10.2337\/diacare.24.11.1936"},{"key":"r006","doi-asserted-by":"publisher","DOI":"10.2337\/dc06-0062"},{"key":"r007","doi-asserted-by":"publisher","DOI":"10.2337\/diacare.23.9.1272"},{"key":"r008","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.163.12.1440"},{"key":"r009","doi-asserted-by":"publisher","DOI":"10.1093\/gerona\/55.1.M43"},{"key":"r010","doi-asserted-by":"publisher","DOI":"10.2337\/dc09-0264"},{"key":"r011","doi-asserted-by":"publisher","DOI":"10.1037\/0278-6133.21.5.419"},{"key":"r012","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-5415.2007.01632.x"},{"key":"r013","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-5415.2008.01813.x"},{"key":"r014","doi-asserted-by":"publisher","DOI":"10.1111\/j.1467-789X.2009.00679.x"},{"key":"r015","doi-asserted-by":"crossref","first-page":"858","DOI":"10.1093\/oxfordjournals.aje.a116747","volume":"137","author":"LaCroix AZ","year":"1993","journal-title":"Am J Epidemiol"},{"key":"r016","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-5415.2000.tb02600.x"},{"key":"r017","doi-asserted-by":"publisher","DOI":"10.2337\/diacare.23.9.1272"},{"key":"r018","doi-asserted-by":"publisher","DOI":"10.1038\/oby.2007.70"},{"key":"r019","doi-asserted-by":"publisher","DOI":"10.1016\/S0197-2456(03)00064-3"},{"key":"r020","unstructured":"MacDonald IL, Zucchini W. Hidden Markov and other models for discrete-valued time series. London: Chapman and Hall, 1997."},{"key":"r021","doi-asserted-by":"publisher","DOI":"10.1016\/j.apmr.2008.05.013"},{"key":"r022","doi-asserted-by":"publisher","DOI":"10.1038\/oby.2006.101"},{"key":"r023","doi-asserted-by":"publisher","DOI":"10.2337\/dc06-2487"},{"key":"r024","doi-asserted-by":"publisher","DOI":"10.1001\/archinternmed.2010.334"},{"key":"r025","doi-asserted-by":"publisher","DOI":"10.1038\/oby.2006.84"},{"key":"r026","doi-asserted-by":"publisher","DOI":"10.1097\/00005650-199905001-00004"},{"key":"r027","doi-asserted-by":"publisher","DOI":"10.1186\/ar2890"},{"key":"r028","unstructured":"American College of Sports Medicine. ASCM's guidelines for exercise testing and prescription. 7th ed. Philadelphia: Lippincott Williams & Wilkins, 2006."},{"key":"r029","doi-asserted-by":"publisher","DOI":"10.1177\/0049124110378095"},{"key":"r030","doi-asserted-by":"publisher","DOI":"10.1214\/aos\/1176344136"},{"key":"r031","doi-asserted-by":"publisher","DOI":"10.1198\/jcgs.2010.09015"},{"key":"r032","doi-asserted-by":"publisher","DOI":"10.1037\/0022-3514.51.6.1173"},{"key":"r033","unstructured":"MacKinnon DP. Introduction to statistical mediation analysis. New York: Lawrence Erlbaum Associates, 2008."},{"key":"r034","doi-asserted-by":"publisher","DOI":"10.3132\/dvdr.2006.031"},{"key":"r035","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1093\/oxfordjournals.aje.a112608","volume":"108","author":"Paffenbarger RS","year":"1978","journal-title":"Am J Epidemiol"},{"key":"r036","doi-asserted-by":"publisher","DOI":"10.1377\/hlthaff.26.1.38"},{"key":"r037","doi-asserted-by":"publisher","DOI":"10.1093\/geronj\/49.2.M85"},{"key":"r038","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1008234"},{"key":"r039","doi-asserted-by":"publisher","DOI":"10.1038\/oby.2011.230"},{"key":"r040","doi-asserted-by":"publisher","DOI":"10.1038\/ijo.2008.280"},{"key":"r041","doi-asserted-by":"publisher","DOI":"10.1001\/archinternmed.2008.544"},{"key":"r042","doi-asserted-by":"publisher","DOI":"10.1002\/art.20256"},{"key":"r043","doi-asserted-by":"publisher","DOI":"10.1001\/archinternmed.2010.522"}],"container-title":["New England Journal of Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.nejm.org\/doi\/pdf\/10.1056\/NEJMoa1110294","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,6,20]],"date-time":"2017-06-20T16:15:38Z","timestamp":1497975338000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.nejm.org\/doi\/10.1056\/NEJMoa1110294"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,3,29]]},"references-count":42,"journal-issue":{"issue":"13","published-print":{"date-parts":[[2012,3,29]]}},"alternative-id":["10.1056\/NEJMoa1110294"],"URL":"https:\/\/doi.org\/10.1056\/nejmoa1110294","relation":{},"ISSN":["0028-4793","1533-4406"],"issn-type":[{"value":"0028-4793","type":"print"},{"value":"1533-4406","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,3,29]]}}}