{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T20:25:03Z","timestamp":1792095903165,"version":"4.4.0"},"reference-count":18,"publisher":"Massachusetts Medical Society","issue":"12","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["N Engl J Med"],"published-print":{"date-parts":[[2012,9,20]]},"DOI":"10.1056\/nejmoa1114287","type":"journal-article","created":{"date-parts":[[2012,9,19]],"date-time":"2012-09-19T17:01:01Z","timestamp":1348074061000},"page":"1098-1107","source":"Crossref","is-referenced-by-count":1549,"title":["Placebo-Controlled Phase 3 Study of Oral BG-12 for Relapsing Multiple Sclerosis"],"prefix":"10.1056","volume":"367","author":[{"given":"Ralf","family":"Gold","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ludwig","family":"Kappos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Douglas L.","family":"Arnold","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amit","family":"Bar-Or","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gavin","family":"Giovannoni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Krzysztof","family":"Selmaj","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlo","family":"Tornatore","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marianne T.","family":"Sweetser","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Minhua","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah I.","family":"Sheikh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katherine T.","family":"Dawson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"150","reference":[{"key":"r001","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awq386"},{"key":"r002","doi-asserted-by":"publisher","DOI":"10.1007\/s00415-004-0348-9"},{"key":"r003","doi-asserted-by":"publisher","DOI":"10.1093\/toxsci\/kfp274"},{"key":"r004","doi-asserted-by":"publisher","DOI":"10.1124\/jpet.111.190132"},{"key":"r005","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20100977"},{"key":"r006","doi-asserted-by":"crossref","first-page":"4781","DOI":"10.4049\/jimmunol.168.9.4781","volume":"168","author":"Loewe R","year":"2002","journal-title":"J Immunol"},{"key":"r007","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(08)61619-0"},{"key":"r008","doi-asserted-by":"publisher","DOI":"10.1002\/ana.20703"},{"key":"r009","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.46.4.907"},{"key":"r010","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.33.11.1444"},{"key":"r013","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa044397"},{"key":"r014","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1206328"},{"key":"r016","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.56.12.1628"},{"key":"r017","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410390304"},{"key":"r018","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.45.7.1268"},{"key":"r019","doi-asserted-by":"publisher","DOI":"10.1177\/1352458510384496"},{"key":"r020","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa0907839"},{"key":"r021","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa0909494"}],"container-title":["New England Journal of Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.nejm.org\/doi\/pdf\/10.1056\/NEJMoa1114287","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,6,20]],"date-time":"2017-06-20T20:27:39Z","timestamp":1497990459000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.nejm.org\/doi\/abs\/10.1056\/NEJMoa1114287"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,9,20]]},"references-count":18,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2012,9,20]]}},"alternative-id":["10.1056\/NEJMoa1114287"],"URL":"https:\/\/doi.org\/10.1056\/nejmoa1114287","relation":{"has-review":[{"id-type":"doi","id":"10.3410\/f.717965926.793488591","asserted-by":"object"}]},"ISSN":["0028-4793","1533-4406"],"issn-type":[{"value":"0028-4793","type":"print"},{"value":"1533-4406","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,9,20]]}}}