{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,29]],"date-time":"2026-10-29T01:07:38Z","timestamp":1793236058381,"version":"4.5.0"},"reference-count":27,"publisher":"Massachusetts Medical Society","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["N Engl J Med"],"published-print":{"date-parts":[[2013,8,8]]},"DOI":"10.1056\/nejmoa1306220","type":"journal-article","created":{"date-parts":[[2013,6,19]],"date-time":"2013-06-19T17:03:40Z","timestamp":1371661420000},"page":"507-516","source":"Crossref","is-referenced-by-count":1499,"title":["Targeting BTK with Ibrutinib in Relapsed or Refractory Mantle-Cell Lymphoma"],"prefix":"10.1056","volume":"369","author":[{"given":"Michael L.","family":"Wang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simon","family":"Rule","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Martin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andre","family":"Goy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rebecca","family":"Auer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brad S.","family":"Kahl","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wojciech","family":"Jurczak","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ranjana H.","family":"Advani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jorge E.","family":"Romaguera","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael E.","family":"Williams","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jacqueline C.","family":"Barrientos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ewa","family":"Chmielowska","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John","family":"Radford","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephan","family":"Stilgenbauer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin","family":"Dreyling","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wieslaw Wiktor","family":"Jedrzejczak","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Johnson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephen E.","family":"Spurgeon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lei","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liang","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kate","family":"Newberry","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhishuo","family":"Ou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nancy","family":"Cheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bingliang","family":"Fang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jesse","family":"McGreivy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fong","family":"Clow","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joseph J.","family":"Buggy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Betty Y.","family":"Chang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Darrin M.","family":"Beaupre","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lori A.","family":"Kunkel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kristie A.","family":"Blum","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"150","reference":[{"key":"r001","doi-asserted-by":"crossref","first-page":"3909","DOI":"10.1182\/blood.V89.11.3909","volume":"89","year":"1997","journal-title":"Blood"},{"key":"r002","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1111\/j.1365-2141.2010.08228.x","volume":"150","author":"Romaguera JE","year":"2010","journal-title":"Br J Haematol"},{"key":"r003","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2012.44.4281"},{"key":"r004","doi-asserted-by":"publisher","DOI":"10.1038\/nature08638"},{"key":"r005","doi-asserted-by":"publisher","DOI":"10.1007\/s11899-012-0127-0"},{"key":"r006","doi-asserted-by":"publisher","DOI":"10.3109\/08830185.2012.664797"},{"key":"r007","doi-asserted-by":"publisher","DOI":"10.1016\/j.cellsig.2012.09.008"},{"key":"r008","doi-asserted-by":"publisher","DOI":"10.1038\/nrd3655"},{"key":"r009","doi-asserted-by":"publisher","DOI":"10.18632\/oncotarget.426"},{"key":"r010","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2011-03-343434"},{"key":"r011","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2141.2005.05883.x"},{"key":"r012","doi-asserted-by":"publisher","unstructured":"Chang BY, Francesco M, Steggerda S, et al. Ibrutinib inhibits malignant cell adhesion and migration and reduces tumor burden in lymph node and bone marrow in a murine model of mantle cell dissemination and progression. Presented at the American Association for Cancer Research Annual Meeting 2013, Washington, DC, April 6\u201310, 2013.","DOI":"10.1158\/1538-7445.AM2013-923"},{"key":"r013","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2011-01-328484"},{"key":"r014","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2012.42.7906"},{"key":"r015","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1215637"},{"key":"r016","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2006.09.2403"},{"key":"r018","doi-asserted-by":"publisher","DOI":"10.1016\/0197-2456(89)90015-9"},{"key":"r019","doi-asserted-by":"publisher","DOI":"10.2307\/2281868"},{"key":"r020","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2011-11-390989"},{"key":"r021","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2011-02-336065"},{"key":"r022","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-07-4409"},{"key":"r024","doi-asserted-by":"publisher","first-page":"1169","DOI":"10.1200\/JCO.1994.12.6.1169","volume":"12","author":"Velasquez WS","year":"1994","journal-title":"J Clin Oncol"},{"key":"r025","doi-asserted-by":"publisher","first-page":"1734","DOI":"10.1200\/JCO.1995.13.7.1734","volume":"13","author":"Rodriguez MA","year":"1995","journal-title":"J Clin Oncol"},{"key":"r026","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.23880"},{"key":"r027","doi-asserted-by":"publisher","DOI":"10.1093\/annonc\/mdg704"},{"key":"r028","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2008.20.7977"},{"key":"r029","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2006.07.9665"}],"container-title":["New England Journal of Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.nejm.org\/doi\/pdf\/10.1056\/NEJMoa1306220","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,12]],"date-time":"2024-05-12T12:46:08Z","timestamp":1715517968000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.nejm.org\/doi\/10.1056\/NEJMoa1306220"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,8,8]]},"references-count":27,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2013,8,8]]}},"alternative-id":["10.1056\/NEJMoa1306220"],"URL":"https:\/\/doi.org\/10.1056\/nejmoa1306220","relation":{"has-review":[{"id-type":"doi","id":"10.3410\/f.718021375.793481342","asserted-by":"object"},{"id-type":"doi","id":"10.3410\/f.718021375.793481853","asserted-by":"object"},{"id-type":"doi","id":"10.3410\/f.718021375.793486032","asserted-by":"object"},{"id-type":"doi","id":"10.3410\/f.718021375.793479401","asserted-by":"object"}]},"ISSN":["0028-4793","1533-4406"],"issn-type":[{"value":"0028-4793","type":"print"},{"value":"1533-4406","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,8,8]]}}}