{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T16:28:14Z","timestamp":1791390494539,"version":"4.3.3"},"reference-count":27,"publisher":"Massachusetts Medical Society","issue":"22","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["N Engl J Med"],"published-print":{"date-parts":[[2014,11,27]]},"DOI":"10.1056\/nejmoa1404731","type":"journal-article","created":{"date-parts":[[2014,11,18]],"date-time":"2014-11-18T12:48:53Z","timestamp":1416314933000},"page":"2061-2071","source":"Crossref","is-referenced-by-count":487,"title":["Atenolol versus Losartan in Children and Young Adults with Marfan's Syndrome"],"prefix":"10.1056","volume":"371","author":[{"given":"Ronald V.","family":"Lacro","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Harry C.","family":"Dietz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lynn A.","family":"Sleeper","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anji T.","family":"Yetman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Timothy J.","family":"Bradley","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steven D.","family":"Colan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gail D.","family":"Pearson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E. Seda","family":"Selamet Tierney","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jami C.","family":"Levine","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew M.","family":"Atz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D. Woodrow","family":"Benson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alan C.","family":"Braverman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shan","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julie","family":"De Backer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bruce D.","family":"Gelb","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul D.","family":"Grossfeld","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gloria L.","family":"Klein","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wyman W.","family":"Lai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aimee","family":"Liou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bart L.","family":"Loeys","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Larry W.","family":"Markham","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aaron K.","family":"Olson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephen M.","family":"Paridon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Victoria L.","family":"Pemberton","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mary Ella","family":"Pierpont","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Reed E.","family":"Pyeritz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elizabeth","family":"Radojewski","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mary J.","family":"Roman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Angela M.","family":"Sharkey","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mario P.","family":"Stylianou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephanie Burns","family":"Wechsler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luciana T.","family":"Young","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lynn","family":"Mahony","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"150","reference":[{"key":"r001","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(05)67789-6"},{"key":"r002","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199405123301902"},{"key":"r003","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000155243.70456.F4"},{"key":"r004","doi-asserted-by":"publisher","DOI":"10.1038\/352337a0"},{"key":"r005","doi-asserted-by":"publisher","DOI":"10.1172\/JCI42014"},{"key":"r006","doi-asserted-by":"publisher","DOI":"10.1038\/nature10145"},{"key":"r007","doi-asserted-by":"publisher","DOI":"10.1161\/01.HYP.23.5.587"},{"key":"r008","doi-asserted-by":"publisher","DOI":"10.1016\/S0895-7061(99)00152-1"},{"key":"r009","doi-asserted-by":"publisher","DOI":"10.1152\/ajprenal.00139.2003"},{"key":"r010","doi-asserted-by":"publisher","DOI":"10.1126\/science.1124287"},{"key":"r011","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa0706585"},{"key":"r012","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2013.06.019"},{"key":"r013","doi-asserted-by":"publisher","DOI":"10.1016\/j.ahj.2007.06.024"},{"key":"r014","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1096-8628(19960424)62:4<417::AID-AJMG15>3.0.CO;2-R"},{"key":"r015","doi-asserted-by":"publisher","DOI":"10.1038\/ng1511"},{"key":"r016","unstructured":"Greally MT. Shprintzen-Goldberg syndrome. In: Pagon RA, Adam MP, Ardinger HH, et al., eds. GeneReviews. Seattle: University of Washington, 2006 (http:\/\/www.ncbi.nlm.nih.gov\/books\/NBK1277)."},{"key":"r017","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.10312"},{"key":"r018","doi-asserted-by":"publisher","DOI":"10.1016\/0021-9681(74)90015-0"},{"key":"r019","doi-asserted-by":"publisher","DOI":"10.1016\/j.echo.2013.02.018"},{"key":"r021","doi-asserted-by":"publisher","DOI":"10.1016\/j.ahj.2013.02.019"},{"key":"r022","doi-asserted-by":"publisher","DOI":"10.1016\/j.mayocp.2012.11.005"},{"key":"r023","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/eht334"},{"key":"r024","doi-asserted-by":"publisher","DOI":"10.2459\/JCM.0b013e3283232a45"},{"key":"r025","doi-asserted-by":"publisher","DOI":"10.1016\/j.acvd.2010.04.008"},{"key":"r026","doi-asserted-by":"publisher","DOI":"10.1016\/j.recesp.2011.02.009"},{"key":"r027","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2010.12.070"},{"key":"r028","doi-asserted-by":"publisher","DOI":"10.1186\/1745-6215-14-408"}],"container-title":["New England Journal of Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.nejm.org\/doi\/pdf\/10.1056\/NEJMoa1404731","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,5,8]],"date-time":"2017-05-08T18:06:15Z","timestamp":1494266775000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.nejm.org\/doi\/10.1056\/NEJMoa1404731"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,11,27]]},"references-count":27,"journal-issue":{"issue":"22","published-print":{"date-parts":[[2014,11,27]]}},"alternative-id":["10.1056\/NEJMoa1404731"],"URL":"https:\/\/doi.org\/10.1056\/nejmoa1404731","relation":{},"ISSN":["0028-4793","1533-4406"],"issn-type":[{"value":"0028-4793","type":"print"},{"value":"1533-4406","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,11,27]]}}}