{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T21:16:17Z","timestamp":1792444577287,"version":"4.5.0"},"reference-count":35,"publisher":"Massachusetts Medical Society","issue":"26","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["N Engl J Med"],"published-print":{"date-parts":[[2016,6,30]]},"DOI":"10.1056\/nejmoa1513098","type":"journal-article","created":{"date-parts":[[2016,6,29]],"date-time":"2016-06-29T19:20:45Z","timestamp":1467228045000},"page":"2530-2541","source":"Crossref","is-referenced-by-count":444,"title":["Efficacy and Safety of Midostaurin in Advanced Systemic Mastocytosis"],"prefix":"10.1056","volume":"374","author":[{"given":"Jason","family":"Gotlib","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hanneke C.","family":"Kluin-Nelemans","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tracy I.","family":"George","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cem","family":"Akin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karl","family":"Sotlar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olivier","family":"Hermine","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Farrukh T.","family":"Awan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elizabeth","family":"Hexner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael J.","family":"Mauro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David W.","family":"Sternberg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthieu","family":"Villeneuve","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alice","family":"Huntsman Labed","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eric J.","family":"Stanek","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karin","family":"Hartmann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hans-Peter","family":"Horny","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Valent","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andreas","family":"Reiter","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"150","reference":[{"key":"r001","doi-asserted-by":"publisher","DOI":"10.1016\/S0145-2126(02)00168-6"},{"key":"r002","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2006-04-015545"},{"key":"r003","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmoldx.2010.10.004"},{"key":"r004","unstructured":"Horny MP, Metcalfe DD, Bennett JM. Mastocytosis. In: Swerdlow SH, Campo E, Harris NL, eds. WHO classification of tumors of hematopoietic and lymphoid tissues. Lyon, France: International Agency for Research and Cancer, 2008:54-63."},{"key":"r005","doi-asserted-by":"publisher","DOI":"10.1016\/j.hoc.2012.08.008"},{"key":"r006","doi-asserted-by":"publisher","DOI":"10.1002\/ajh.23931"},{"key":"r007","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2362.2007.01807.x"},{"key":"r008","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2012-09-458521"},{"key":"r009","doi-asserted-by":"publisher","DOI":"10.1002\/path.2677"},{"key":"r010","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2009-02-205237"},{"key":"r011","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2012-07-442400"},{"key":"r012","doi-asserted-by":"publisher","DOI":"10.1111\/bjh.12916"},{"key":"r013","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.1995.tb08689.x"},{"key":"r014","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM200101253440415"},{"key":"r015","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2003-05-1699"},{"key":"r016","doi-asserted-by":"publisher","DOI":"10.1016\/S0145-2126(03)00259-5"},{"key":"r017","doi-asserted-by":"publisher","DOI":"10.1016\/S0145-2126(03)00185-1"},{"key":"r018","doi-asserted-by":"publisher","DOI":"10.1002\/ajh.21561"},{"key":"r019","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2014-12-614743"},{"key":"r021","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2004-12-4617"},{"key":"r022","first-page":"17","volume":"15","author":"Fabbro D","year":"2000","journal-title":"Anticancer Drug Des"},{"key":"r024","doi-asserted-by":"publisher","DOI":"10.1016\/S0145-2126(01)00038-8"},{"key":"r025","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2002-04-1199"},{"key":"r026","first-page":"3671","volume":"96","author":"Cheson BD","year":"2000","journal-title":"Blood"},{"key":"r027","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2005-10-4149"},{"key":"r028","doi-asserted-by":"publisher","DOI":"10.1016\/0959-8049(94)90182-1"},{"key":"r029","doi-asserted-by":"publisher","DOI":"10.1097\/00005650-199603000-00003"},{"key":"r030","unstructured":"Ware JE, Kosinski M, Gandek B, et al. User\u2019s manual for the SF-12v2 Health Survey, second edition. Lincoln, RI: QualityMetric, 2010."},{"key":"r031","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-62703-357-2_4"},{"key":"r032","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1002028"},{"key":"r033","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2222.2009.03353.x"},{"key":"r034","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2014.55.2018"},{"key":"r035","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2005-04-1568"},{"key":"r036","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2013-04-496448"},{"key":"r037","doi-asserted-by":"publisher","DOI":"10.1038\/leu.2015.4"}],"container-title":["New England Journal of Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.nejm.org\/doi\/pdf\/10.1056\/NEJMoa1513098","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2016,11,2]],"date-time":"2016-11-02T15:35:59Z","timestamp":1478100959000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.nejm.org\/doi\/10.1056\/NEJMoa1513098"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,6,30]]},"references-count":35,"journal-issue":{"issue":"26","published-print":{"date-parts":[[2016,6,30]]}},"alternative-id":["10.1056\/NEJMoa1513098"],"URL":"https:\/\/doi.org\/10.1056\/nejmoa1513098","relation":{"has-review":[{"id-type":"doi","id":"10.3410\/f.726470483.793524516","asserted-by":"object"},{"id-type":"doi","id":"10.3410\/f.726470483.793520587","asserted-by":"object"}]},"ISSN":["0028-4793","1533-4406"],"issn-type":[{"value":"0028-4793","type":"print"},{"value":"1533-4406","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,6,30]]}}}