{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T16:02:42Z","timestamp":1791648162729,"version":"4.3.4"},"reference-count":57,"publisher":"Massachusetts Medical Society","issue":"25","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["N Engl J Med"],"published-print":{"date-parts":[[2016,6,23]]},"DOI":"10.1056\/nejmoa1513137","type":"journal-article","created":{"date-parts":[[2016,6,23]],"date-time":"2016-06-23T22:07:55Z","timestamp":1466719675000},"page":"2453-2464","source":"Crossref","is-referenced-by-count":511,"title":["A Worldwide Map of\n                    <i>Plasmodium falciparum<\/i>\n                    K13-Propeller Polymorphisms"],"prefix":"10.1056","volume":"374","author":[{"given":"Didier","family":"M\u00e9nard","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nimol","family":"Khim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Johann","family":"Beghain","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ayola A.","family":"Adegnika","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammad","family":"Shafiul-Alam","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olukemi","family":"Amodu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ghulam","family":"Rahim-Awab","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C\u00e9line","family":"Barnadas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antoine","family":"Berry","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yap","family":"Boum","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria D.","family":"Bustos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jun","family":"Cao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jun-Hu","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Louis","family":"Collet","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liwang","family":"Cui","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Garib-Das","family":"Thakur","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alioune","family":"Dieye","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Djibrine","family":"Djall\u00e9","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Monique A.","family":"Dorkenoo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carole E.","family":"Eboumbou-Moukoko","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fe-Esperanza-Caridad J.","family":"Espino","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thierry","family":"Fandeur","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria-Fatima","family":"Ferreira-da-Cruz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abebe A.","family":"Fola","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hans-Peter","family":"Fuehrer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdillahi M.","family":"Hassan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Socrates","family":"Herrera","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bouasy","family":"Hongvanthong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sandrine","family":"Houz\u00e9","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maman L.","family":"Ibrahim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammad","family":"Jahirul-Karim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lubin","family":"Jiang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shigeyuki","family":"Kano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wasif","family":"Ali-Khan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maniphone","family":"Khanthavong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter G.","family":"Kremsner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcus","family":"Lacerda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rithea","family":"Leang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mindy","family":"Leelawong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mei","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Khin","family":"Lin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean-Baptiste","family":"Mazarati","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sandie","family":"M\u00e9nard","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isabelle","family":"Morlais","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hypolite","family":"Muhindo-Mavoko","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lise","family":"Musset","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kesara","family":"Na-Bangchang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Nambozi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karamoko","family":"Niar\u00e9","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Harald","family":"Noedl","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean-Bosco","family":"Ou\u00e9draogo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dylan R.","family":"Pillai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bruno","family":"Pradines","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bui","family":"Quang-Phuc","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Ramharter","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Milijaona","family":"Randrianarivelojosia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jetsumon","family":"Sattabongkot","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdiqani","family":"Sheikh-Omar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kigbafori D.","family":"Silu\u00e9","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sodiomon B.","family":"Sirima","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Colin","family":"Sutherland","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Din","family":"Syafruddin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rachida","family":"Tahar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lin-Hua","family":"Tang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Offianan A.","family":"Tour\u00e9","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patrick","family":"Tshibangu-wa-Tshibangu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"In\u00e8s","family":"Vigan-Womas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marian","family":"Warsame","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lyndes","family":"Wini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sedigheh","family":"Zakeri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saorin","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rotha","family":"Eam","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura","family":"Berne","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chanra","family":"Khean","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sophy","family":"Chy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Malen","family":"Ken","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kaknika","family":"Loch","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lydie","family":"Canier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Valentine","family":"Duru","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eric","family":"Legrand","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean-Christophe","family":"Barale","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Barbara","family":"Stokes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Judith","family":"Straimer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Benoit","family":"Witkowski","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David A.","family":"Fidock","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christophe","family":"Rogier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pascal","family":"Ringwald","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frederic","family":"Ariey","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Odile","family":"Mercereau-Puijalon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"150","reference":[{"key":"r002","doi-asserted-by":"publisher","DOI":"10.1038\/nature15535"},{"key":"r005","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(13)70252-4"},{"key":"r006","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.01868-12"},{"key":"r007","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-3156.2006.01739.x"},{"key":"r008","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-3156.2006.01690.x"},{"key":"r009","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa0808859"},{"key":"r010","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMc0805011"},{"key":"r011","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(12)70181-0"},{"key":"r012","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1314981"},{"key":"r013","doi-asserted-by":"publisher","DOI":"10.1186\/1475-2875-11-355"},{"key":"r014","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/jiv249"},{"key":"r015","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0057689"},{"key":"r016","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(12)60484-X"},{"key":"r017","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.02746-14"},{"key":"r018","doi-asserted-by":"publisher","DOI":"10.1126\/science.1098876"},{"key":"r019","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(02)00239-6"},{"key":"r020","doi-asserted-by":"crossref","first-page":"12","DOI":"10.4269\/ajtmh.2001.64.12","volume":"64","author":"Trape JF","year":"2001","journal-title":"Am J Trop Med Hyg"},{"key":"r021","doi-asserted-by":"publisher","DOI":"10.1016\/S1471-4922(02)02249-3"},{"key":"r022","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1000830"},{"key":"r024","doi-asserted-by":"publisher","DOI":"10.1038\/nature12876"},{"key":"r025","doi-asserted-by":"publisher","DOI":"10.1126\/science.1260867"},{"key":"r026","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.03055-14"},{"key":"r027","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(14)70777-7"},{"key":"r028","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/jiu491"},{"key":"r029","doi-asserted-by":"publisher","DOI":"10.1038\/ng.3189"},{"key":"r030","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.14-0664"},{"key":"r031","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.04632-14"},{"key":"r032","doi-asserted-by":"publisher","DOI":"10.1186\/1475-2875-11-243"},{"key":"r033","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.04843-14"},{"key":"r034","doi-asserted-by":"publisher","DOI":"10.1186\/1475-2875-13-431"},{"key":"r035","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0105690"},{"key":"r036","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.00921-15"},{"key":"r037","doi-asserted-by":"publisher","DOI":"10.3201\/eid2103.140898"},{"key":"r038","first-page":"1352","volume":"211","author":"Kamau E","year":"2015","journal-title":"J Infect Dis"},{"key":"r039","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.14-0605"},{"key":"r040","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/jiu467"},{"key":"r041","doi-asserted-by":"publisher","DOI":"10.1186\/1475-2875-13-472"},{"key":"r042","doi-asserted-by":"publisher","DOI":"10.1038\/srep03318"},{"key":"r043","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/jiu358"},{"key":"r044","doi-asserted-by":"publisher","DOI":"10.3201\/eid2107.150213"},{"key":"r045","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(15)70046-0"},{"key":"r046","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(14)70826-6"},{"key":"r047","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.76.10.5269"},{"key":"r048","doi-asserted-by":"crossref","unstructured":"Nei M. Molecular evolutionary genetics. New York: Columbia University Press, 1987.","DOI":"10.7312\/nei-92038"},{"key":"r049","doi-asserted-by":"crossref","unstructured":"Kimura M. The neutral theory of molecular evolution. Cambridge, United Kingdom: Cambridge University Press, 1983.","DOI":"10.1017\/CBO9780511623486"},{"key":"r050","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btp187"},{"key":"r051","doi-asserted-by":"publisher","DOI":"10.1093\/molbev\/msu397"},{"key":"r052","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/ciu1160"},{"key":"r053","doi-asserted-by":"publisher","DOI":"10.1186\/s12936-015-0672-9"},{"key":"r054","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(15)70032-0"},{"key":"r055","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1004789"},{"key":"r056","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.04144-14"},{"key":"r058","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0119215"},{"key":"r059","doi-asserted-by":"publisher","DOI":"10.1038\/ng.2624"},{"key":"r060","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/jit082"},{"key":"r061","doi-asserted-by":"publisher","DOI":"10.1186\/s12916-015-0445-x"},{"key":"r062","doi-asserted-by":"publisher","DOI":"10.1038\/nature14412"}],"container-title":["New England Journal of Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.nejm.org\/doi\/pdf\/10.1056\/NEJMoa1513137","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,9,10]],"date-time":"2019-09-10T00:14:49Z","timestamp":1568074489000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.nejm.org\/doi\/10.1056\/NEJMoa1513137"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,6,23]]},"references-count":57,"journal-issue":{"issue":"25","published-print":{"date-parts":[[2016,6,23]]}},"alternative-id":["10.1056\/NEJMoa1513137"],"URL":"https:\/\/doi.org\/10.1056\/nejmoa1513137","relation":{},"ISSN":["0028-4793","1533-4406"],"issn-type":[{"value":"0028-4793","type":"print"},{"value":"1533-4406","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,6,23]]}}}