{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,30]],"date-time":"2026-10-30T04:08:06Z","timestamp":1793333286430,"version":"4.5.0"},"reference-count":24,"publisher":"Massachusetts Medical Society","issue":"16","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["N Engl J Med"],"published-print":{"date-parts":[[2016,10,20]]},"DOI":"10.1056\/nejmoa1607948","type":"journal-article","created":{"date-parts":[[2016,9,18]],"date-time":"2016-09-18T11:00:23Z","timestamp":1474196423000},"page":"1532-1543","source":"Crossref","is-referenced-by-count":1709,"title":["Romosozumab Treatment in Postmenopausal Women with Osteoporosis"],"prefix":"10.1056","volume":"375","author":[{"given":"Felicia","family":"Cosman","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daria B.","family":"Crittenden","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jonathan D.","family":"Adachi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Neil","family":"Binkley","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edward","family":"Czerwinski","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Serge","family":"Ferrari","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lorenz C.","family":"Hofbauer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edith","family":"Lau","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E. Michael","family":"Lewiecki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akimitsu","family":"Miyauchi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cristiano A.F.","family":"Zerbini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cassandra E.","family":"Milmont","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Judy","family":"Maddox","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul D.","family":"Meisner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cesar","family":"Libanati","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andreas","family":"Grauer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"150","reference":[{"key":"r001","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(02)08657-9"},{"key":"r002","doi-asserted-by":"publisher","DOI":"10.1001\/jama.285.6.785"},{"key":"r003","doi-asserted-by":"publisher","DOI":"10.1002\/art.10787"},{"key":"r004","doi-asserted-by":"publisher","DOI":"10.1007\/s00198-003-1544-7"},{"key":"r005","doi-asserted-by":"publisher","DOI":"10.1007\/s00198-014-2827-x"},{"key":"r006","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/10.5.537"},{"key":"r007","doi-asserted-by":"publisher","DOI":"10.1086\/318811"},{"key":"r008","doi-asserted-by":"crossref","first-page":"1842","DOI":"10.1096\/fj.05-4221fje","volume":"19","author":"Poole KE","year":"2005","journal-title":"FASEB J"},{"key":"r009","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M413274200"},{"key":"r010","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1305224"},{"key":"r011","doi-asserted-by":"publisher","DOI":"10.1002\/jbmr.173"},{"key":"r012","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(15)61120-5"},{"key":"r013","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.164.18.2024"},{"key":"r014","doi-asserted-by":"publisher","DOI":"10.1002\/jbmr.5650080915"},{"key":"r015","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-84-4-393"},{"key":"r016","doi-asserted-by":"publisher","DOI":"10.1046\/j.1532-5415.2003.51110.x"},{"key":"r017","doi-asserted-by":"publisher","DOI":"10.1093\/gerona\/glt093"},{"key":"r018","doi-asserted-by":"publisher","DOI":"10.1016\/j.bone.2004.03.035"},{"key":"r019","doi-asserted-by":"publisher","DOI":"10.1007\/s00198-012-1964-3"},{"key":"r020","doi-asserted-by":"publisher","DOI":"10.1007\/s11657-015-0224-5"},{"key":"r021","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M504308200"},{"key":"r022","doi-asserted-by":"publisher","DOI":"10.1359\/jbmr.061002"},{"key":"r023","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0025900"},{"key":"r024","doi-asserted-by":"publisher","DOI":"10.1002\/jbmr.2152"}],"container-title":["New England Journal of Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.nejm.org\/doi\/pdf\/10.1056\/NEJMoa1607948","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,9,13]],"date-time":"2019-09-13T14:07:54Z","timestamp":1568383674000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.nejm.org\/doi\/10.1056\/NEJMoa1607948"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,10,20]]},"references-count":24,"journal-issue":{"issue":"16","published-print":{"date-parts":[[2016,10,20]]}},"alternative-id":["10.1056\/NEJMoa1607948"],"URL":"https:\/\/doi.org\/10.1056\/nejmoa1607948","relation":{"has-review":[{"id-type":"doi","id":"10.3410\/f.726756044.793524616","asserted-by":"object"},{"id-type":"doi","id":"10.3410\/f.726756044.793525428","asserted-by":"object"}]},"ISSN":["0028-4793","1533-4406"],"issn-type":[{"value":"0028-4793","type":"print"},{"value":"1533-4406","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,10,20]]}}}