{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T16:10:36Z","timestamp":1791648636013,"version":"4.3.4"},"reference-count":33,"publisher":"Massachusetts Medical Society","issue":"11","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["N Engl J Med"],"published-print":{"date-parts":[[2018,3,15]]},"DOI":"10.1056\/nejmoa1712770","type":"journal-article","created":{"date-parts":[[2018,3,14]],"date-time":"2018-03-14T21:00:41Z","timestamp":1521061241000},"page":"995-1003","source":"Crossref","is-referenced-by-count":501,"title":["Injection of Cultured Cells with a ROCK Inhibitor for Bullous Keratopathy"],"prefix":"10.1056","volume":"378","author":[{"given":"Shigeru","family":"Kinoshita","sequence":"first","affiliation":[{"name":"From the Departments of Frontier Medical Science and Technology for Ophthalmology (S.K., T.N., M.T., M.H.), Ophthalmology (M.U., K.I., H.T., Y.Y., T.I., J.B., C.S., J.H.), and Biostatistics (I.Y., S.T.), Kyoto Prefectural University of Medicine, and the Department of Biomedical Engineering, Doshisha University (N.K., N.O.) \u2014 both in Kyoto, Japan."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Noriko","family":"Koizumi","sequence":"additional","affiliation":[{"name":"From the Departments of Frontier Medical Science and Technology for Ophthalmology (S.K., T.N., M.T., M.H.), Ophthalmology (M.U., K.I., H.T., Y.Y., T.I., J.B., C.S., J.H.), and Biostatistics (I.Y., S.T.), Kyoto Prefectural University of Medicine, and the Department of Biomedical Engineering, Doshisha University (N.K., N.O.) \u2014 both in Kyoto, Japan."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Morio","family":"Ueno","sequence":"additional","affiliation":[{"name":"From the Departments of Frontier Medical Science and Technology for Ophthalmology (S.K., T.N., M.T., M.H.), Ophthalmology (M.U., K.I., H.T., Y.Y., T.I., J.B., C.S., J.H.), and Biostatistics (I.Y., S.T.), Kyoto Prefectural University of Medicine, and the Department of Biomedical Engineering, Doshisha University (N.K., N.O.) \u2014 both in Kyoto, Japan."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naoki","family":"Okumura","sequence":"additional","affiliation":[{"name":"From the Departments of Frontier Medical Science and Technology for Ophthalmology (S.K., T.N., M.T., M.H.), Ophthalmology (M.U., K.I., H.T., Y.Y., T.I., J.B., C.S., J.H.), and Biostatistics (I.Y., S.T.), Kyoto Prefectural University of Medicine, and the Department of Biomedical Engineering, Doshisha University (N.K., N.O.) \u2014 both in Kyoto, Japan."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kojiro","family":"Imai","sequence":"additional","affiliation":[{"name":"From the Departments of Frontier Medical Science and Technology for Ophthalmology (S.K., T.N., M.T., M.H.), Ophthalmology (M.U., K.I., H.T., Y.Y., T.I., J.B., C.S., J.H.), and Biostatistics (I.Y., S.T.), Kyoto Prefectural University of Medicine, and the Department of Biomedical Engineering, Doshisha University (N.K., N.O.) \u2014 both in Kyoto, Japan."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroshi","family":"Tanaka","sequence":"additional","affiliation":[{"name":"From the Departments of Frontier Medical Science and Technology for Ophthalmology (S.K., T.N., M.T., M.H.), Ophthalmology (M.U., K.I., H.T., Y.Y., T.I., J.B., C.S., J.H.), and Biostatistics (I.Y., S.T.), Kyoto Prefectural University of Medicine, and the Department of Biomedical Engineering, Doshisha University (N.K., N.O.) \u2014 both in Kyoto, Japan."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuji","family":"Yamamoto","sequence":"additional","affiliation":[{"name":"From the Departments of Frontier Medical Science and Technology for Ophthalmology (S.K., T.N., M.T., M.H.), Ophthalmology (M.U., K.I., H.T., Y.Y., T.I., J.B., C.S., J.H.), and Biostatistics (I.Y., S.T.), Kyoto Prefectural University of Medicine, and the Department of Biomedical Engineering, Doshisha University (N.K., N.O.) \u2014 both in Kyoto, Japan."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takahiro","family":"Nakamura","sequence":"additional","affiliation":[{"name":"From the Departments of Frontier Medical Science and Technology for Ophthalmology (S.K., T.N., M.T., M.H.), Ophthalmology (M.U., K.I., H.T., Y.Y., T.I., J.B., C.S., J.H.), and Biostatistics (I.Y., S.T.), Kyoto Prefectural University of Medicine, and the Department of Biomedical Engineering, Doshisha University (N.K., N.O.) \u2014 both in Kyoto, Japan."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tsutomu","family":"Inatomi","sequence":"additional","affiliation":[{"name":"From the Departments of Frontier Medical Science and Technology for Ophthalmology (S.K., T.N., M.T., M.H.), Ophthalmology (M.U., K.I., H.T., Y.Y., T.I., J.B., C.S., J.H.), and Biostatistics (I.Y., S.T.), Kyoto Prefectural University of Medicine, and the Department of Biomedical Engineering, Doshisha University (N.K., N.O.) \u2014 both in Kyoto, Japan."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John","family":"Bush","sequence":"additional","affiliation":[{"name":"From the Departments of Frontier Medical Science and Technology for Ophthalmology (S.K., T.N., M.T., M.H.), Ophthalmology (M.U., K.I., H.T., Y.Y., T.I., J.B., C.S., J.H.), and Biostatistics (I.Y., S.T.), Kyoto Prefectural University of Medicine, and the Department of Biomedical Engineering, Doshisha University (N.K., N.O.) \u2014 both in Kyoto, Japan."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Munetoyo","family":"Toda","sequence":"additional","affiliation":[{"name":"From the Departments of Frontier Medical Science and Technology for Ophthalmology (S.K., T.N., M.T., M.H.), Ophthalmology (M.U., K.I., H.T., Y.Y., T.I., J.B., C.S., J.H.), and Biostatistics (I.Y., S.T.), Kyoto Prefectural University of Medicine, and the Department of Biomedical Engineering, Doshisha University (N.K., N.O.) \u2014 both in Kyoto, Japan."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michio","family":"Hagiya","sequence":"additional","affiliation":[{"name":"From the Departments of Frontier Medical Science and Technology for Ophthalmology (S.K., T.N., M.T., M.H.), Ophthalmology (M.U., K.I., H.T., Y.Y., T.I., J.B., C.S., J.H.), and Biostatistics (I.Y., S.T.), Kyoto Prefectural University of Medicine, and the Department of Biomedical Engineering, Doshisha University (N.K., N.O.) \u2014 both in Kyoto, Japan."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isao","family":"Yokota","sequence":"additional","affiliation":[{"name":"From the Departments of Frontier Medical Science and Technology for Ophthalmology (S.K., T.N., M.T., M.H.), Ophthalmology (M.U., K.I., H.T., Y.Y., T.I., J.B., C.S., J.H.), and Biostatistics (I.Y., S.T.), Kyoto Prefectural University of Medicine, and the Department of Biomedical Engineering, Doshisha University (N.K., N.O.) \u2014 both in Kyoto, Japan."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Satoshi","family":"Teramukai","sequence":"additional","affiliation":[{"name":"From the Departments of Frontier Medical Science and Technology for Ophthalmology (S.K., T.N., M.T., M.H.), Ophthalmology (M.U., K.I., H.T., Y.Y., T.I., J.B., C.S., J.H.), and Biostatistics (I.Y., S.T.), Kyoto Prefectural University of Medicine, and the Department of Biomedical Engineering, Doshisha University (N.K., N.O.) \u2014 both in Kyoto, Japan."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chie","family":"Sotozono","sequence":"additional","affiliation":[{"name":"From the Departments of Frontier Medical Science and Technology for Ophthalmology (S.K., T.N., M.T., M.H.), Ophthalmology (M.U., K.I., H.T., Y.Y., T.I., J.B., C.S., J.H.), and Biostatistics (I.Y., S.T.), Kyoto Prefectural University of Medicine, and the Department of Biomedical Engineering, Doshisha University (N.K., N.O.) \u2014 both in Kyoto, Japan."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junji","family":"Hamuro","sequence":"additional","affiliation":[{"name":"From the Departments of Frontier Medical Science and Technology for Ophthalmology (S.K., T.N., M.T., M.H.), Ophthalmology (M.U., K.I., H.T., Y.Y., T.I., J.B., C.S., J.H.), and Biostatistics (I.Y., S.T.), Kyoto Prefectural University of Medicine, and the Department of Biomedical Engineering, Doshisha University (N.K., N.O.) \u2014 both in Kyoto, Japan."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"150","reference":[{"key":"r1","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-323-05714-1.00004-2"},{"key":"r2","first-page":"229","volume":"96","author":"Bourne WM","year":"1998","journal-title":"Trans Am Ophthalmol Soc"},{"key":"r3","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(12)60437-1"},{"key":"r4","volume-title":"2015 Eye banking statistical report.","year":"2016"},{"key":"r5","doi-asserted-by":"publisher","DOI":"10.1001\/jamaophthalmol.2015.4776"},{"key":"r6","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajo.2007.09.021"},{"key":"r7","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2009.07.010"},{"key":"r8","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajo.2016.07.002"},{"key":"r9","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2015.09.023"},{"key":"r10","doi-asserted-by":"publisher","DOI":"10.1097\/ICO.0000000000000915"},{"key":"r11","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.12-11320"},{"key":"r12","doi-asserted-by":"publisher","DOI":"10.1007\/BF02624143"},{"key":"r13","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.03-0814"},{"key":"r14","doi-asserted-by":"publisher","DOI":"10.1097\/01.ico.0000136666.63870.18"},{"key":"r15","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.03-1174"},{"key":"r16","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.03-0016"},{"key":"r17","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.05-0245"},{"key":"r18","doi-asserted-by":"publisher","DOI":"10.1016\/j.exer.2004.08.021"},{"key":"r19","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.05-0251"},{"key":"r20","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0051427"},{"key":"r21","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.07-0567"},{"key":"r22","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0028310"},{"key":"r23","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.08-2634"},{"key":"r24","doi-asserted-by":"publisher","DOI":"10.1038\/nature03228"},{"key":"r25","doi-asserted-by":"publisher","DOI":"10.1159\/000101298"},{"key":"r26","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajpath.2012.03.033"},{"key":"r27","doi-asserted-by":"publisher","DOI":"10.1038\/srep26113"},{"key":"r28","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.16-21170"},{"key":"r29","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.16-19770"},{"key":"r30","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.16-20703"},{"key":"r31","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcrs.2004.01.014"},{"key":"r32","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.15-19020"},{"key":"r33","doi-asserted-by":"publisher","DOI":"10.1038\/nri1224"}],"container-title":["New England Journal of Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.nejm.org\/doi\/pdf\/10.1056\/NEJMoa1712770","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2018,3,23]],"date-time":"2018-03-23T14:54:02Z","timestamp":1521816842000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.nejm.org\/doi\/10.1056\/NEJMoa1712770"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,3,15]]},"references-count":33,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2018,3,15]]}},"alternative-id":["10.1056\/NEJMoa1712770"],"URL":"https:\/\/doi.org\/10.1056\/nejmoa1712770","relation":{},"ISSN":["0028-4793","1533-4406"],"issn-type":[{"value":"0028-4793","type":"print"},{"value":"1533-4406","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,3,15]]}}}