{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,18]],"date-time":"2026-10-18T05:39:30Z","timestamp":1792301970340,"version":"4.4.0"},"reference-count":20,"publisher":"Massachusetts Medical Society","issue":"3","license":[{"start":{"date-parts":[[2018,7,19]],"date-time":"2018-07-19T00:00:00Z","timestamp":1531958400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/www.nejmgroup.org\/legal\/terms-of-use.htm"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["2U01NS062835"],"award-info":[{"award-number":["2U01NS062835"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["N Engl J Med"],"published-print":{"date-parts":[[2018,7,19]]},"DOI":"10.1056\/nejmoa1800410","type":"journal-article","created":{"date-parts":[[2018,5,16]],"date-time":"2018-05-16T06:01:11Z","timestamp":1526450471000},"page":"215-225","source":"Crossref","is-referenced-by-count":1232,"title":["Clopidogrel and Aspirin in Acute Ischemic Stroke and High-Risk TIA"],"prefix":"10.1056","volume":"379","author":[{"given":"S. Claiborne","family":"Johnston","sequence":"first","affiliation":[{"name":"From the Dean\u2019s Office, Dell Medical School, University of Texas at Austin, Austin (S.C.J.); the Department of Neurology, University of California, San Francisco, San Francisco (J.D.E., M.F., A.S.K.); the Department of Emergency Medicine, University of Michigan, Ann Arbor (W.B.); the Division of Clinical Research, National Institute of Neurological Disorders and Stroke, Bethesda (R.A.C.), and Emmes, Rockville (A.S.L.) \u2014 both in Maryland; and the Data Coordination Unit, Department of Public Health..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J. Donald","family":"Easton","sequence":"additional","affiliation":[{"name":"From the Dean\u2019s Office, Dell Medical School, University of Texas at Austin, Austin (S.C.J.); the Department of Neurology, University of California, San Francisco, San Francisco (J.D.E., M.F., A.S.K.); the Department of Emergency Medicine, University of Michigan, Ann Arbor (W.B.); the Division of Clinical Research, National Institute of Neurological Disorders and Stroke, Bethesda (R.A.C.), and Emmes, Rockville (A.S.L.) \u2014 both in Maryland; and the Data Coordination Unit, Department of Public Health..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mary","family":"Farrant","sequence":"additional","affiliation":[{"name":"From the Dean\u2019s Office, Dell Medical School, University of Texas at Austin, Austin (S.C.J.); the Department of Neurology, University of California, San Francisco, San Francisco (J.D.E., M.F., A.S.K.); the Department of Emergency Medicine, University of Michigan, Ann Arbor (W.B.); the Division of Clinical Research, National Institute of Neurological Disorders and Stroke, Bethesda (R.A.C.), and Emmes, Rockville (A.S.L.) \u2014 both in Maryland; and the Data Coordination Unit, Department of Public Health..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William","family":"Barsan","sequence":"additional","affiliation":[{"name":"From the Dean\u2019s Office, Dell Medical School, University of Texas at Austin, Austin (S.C.J.); the Department of Neurology, University of California, San Francisco, San Francisco (J.D.E., M.F., A.S.K.); the Department of Emergency Medicine, University of Michigan, Ann Arbor (W.B.); the Division of Clinical Research, National Institute of Neurological Disorders and Stroke, Bethesda (R.A.C.), and Emmes, Rockville (A.S.L.) \u2014 both in Maryland; and the Data Coordination Unit, Department of Public Health..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robin A.","family":"Conwit","sequence":"additional","affiliation":[{"name":"From the Dean\u2019s Office, Dell Medical School, University of Texas at Austin, Austin (S.C.J.); the Department of Neurology, University of California, San Francisco, San Francisco (J.D.E., M.F., A.S.K.); the Department of Emergency Medicine, University of Michigan, Ann Arbor (W.B.); the Division of Clinical Research, National Institute of Neurological Disorders and Stroke, Bethesda (R.A.C.), and Emmes, Rockville (A.S.L.) \u2014 both in Maryland; and the Data Coordination Unit, Department of Public Health..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jordan J.","family":"Elm","sequence":"additional","affiliation":[{"name":"From the Dean\u2019s Office, Dell Medical School, University of Texas at Austin, Austin (S.C.J.); the Department of Neurology, University of California, San Francisco, San Francisco (J.D.E., M.F., A.S.K.); the Department of Emergency Medicine, University of Michigan, Ann Arbor (W.B.); the Division of Clinical Research, National Institute of Neurological Disorders and Stroke, Bethesda (R.A.C.), and Emmes, Rockville (A.S.L.) \u2014 both in Maryland; and the Data Coordination Unit, Department of Public Health..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anthony S.","family":"Kim","sequence":"additional","affiliation":[{"name":"From the Dean\u2019s Office, Dell Medical School, University of Texas at Austin, Austin (S.C.J.); the Department of Neurology, University of California, San Francisco, San Francisco (J.D.E., M.F., A.S.K.); the Department of Emergency Medicine, University of Michigan, Ann Arbor (W.B.); the Division of Clinical Research, National Institute of Neurological Disorders and Stroke, Bethesda (R.A.C.), and Emmes, Rockville (A.S.L.) \u2014 both in Maryland; and the Data Coordination Unit, Department of Public Health..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne S.","family":"Lindblad","sequence":"additional","affiliation":[{"name":"From the Dean\u2019s Office, Dell Medical School, University of Texas at Austin, Austin (S.C.J.); the Department of Neurology, University of California, San Francisco, San Francisco (J.D.E., M.F., A.S.K.); the Department of Emergency Medicine, University of Michigan, Ann Arbor (W.B.); the Division of Clinical Research, National Institute of Neurological Disorders and Stroke, Bethesda (R.A.C.), and Emmes, Rockville (A.S.L.) \u2014 both in Maryland; and the Data Coordination Unit, Department of Public Health..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuko Y.","family":"Palesch","sequence":"additional","affiliation":[{"name":"From the Dean\u2019s Office, Dell Medical School, University of Texas at Austin, Austin (S.C.J.); the Department of Neurology, University of California, San Francisco, San Francisco (J.D.E., M.F., A.S.K.); the Department of Emergency Medicine, University of Michigan, Ann Arbor (W.B.); the Division of Clinical Research, National Institute of Neurological Disorders and Stroke, Bethesda (R.A.C.), and Emmes, Rockville (A.S.L.) \u2014 both in Maryland; and the Data Coordination Unit, Department of Public Health..."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"150","reference":[{"key":"e_1_3_4_2_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.284.22.2901"},{"key":"e_1_3_4_3_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.37991.635266.44"},{"key":"e_1_3_4_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(07)70274-0"},{"key":"e_1_3_4_5_2","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.167.22.2417"},{"key":"e_1_3_4_6_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1412981"},{"key":"e_1_3_4_7_2","doi-asserted-by":"publisher","DOI":"10.1161\/STR.0000000000000024"},{"key":"e_1_3_4_8_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.324.7329.71"},{"key":"e_1_3_4_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(97)04010-5"},{"key":"e_1_3_4_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(97)04011-7"},{"key":"e_1_3_4_11_2","doi-asserted-by":"publisher","DOI":"10.1161\/STR.0000000000000158"},{"key":"e_1_3_4_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2007.11.057"},{"key":"e_1_3_4_13_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1215340"},{"key":"e_1_3_4_14_2","doi-asserted-by":"publisher","DOI":"10.1111\/ijs.12129"},{"key":"e_1_3_4_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(07)60150-0"},{"key":"e_1_3_4_16_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1538-7836.2005.01204.x"},{"key":"e_1_3_4_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(08)70198-4"},{"key":"e_1_3_4_18_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2016.8662"},{"key":"e_1_3_4_19_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1603060"},{"key":"e_1_3_4_20_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(17)32849-0"},{"key":"e_1_3_4_21_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(17)30038-8"}],"container-title":["New England Journal of Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.nejm.org\/doi\/pdf\/10.1056\/NEJMoa1800410","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,3,26]],"date-time":"2024-03-26T20:40:50Z","timestamp":1711485650000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.nejm.org\/doi\/10.1056\/NEJMoa1800410"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,7,19]]},"references-count":20,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2018,7,19]]}},"alternative-id":["10.1056\/NEJMoa1800410"],"URL":"https:\/\/doi.org\/10.1056\/nejmoa1800410","relation":{},"ISSN":["0028-4793","1533-4406"],"issn-type":[{"value":"0028-4793","type":"print"},{"value":"1533-4406","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,7,19]]}}}