{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T22:16:05Z","timestamp":1787004965104,"version":"build-2736575974"},"reference-count":25,"publisher":"Massachusetts Medical Society","issue":"16","license":[{"start":{"date-parts":[[2019,4,18]],"date-time":"2019-04-18T00:00:00Z","timestamp":1555545600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/www.nejmgroup.org\/legal\/terms-of-use.htm"}],"funder":[{"DOI":"10.13039\/501100002768","name":"Ministry of Economic Administration (MOEA), Taiwan","doi-asserted-by":"publisher","award":["104-EC-17-A-20-15-0007 - Support Phase II clinical"],"award-info":[{"award-number":["104-EC-17-A-20-15-0007 - Support Phase II clinical"]}],"id":[{"id":"10.13039\/501100002768","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002768","name":"Ministry of Economic Administration (MOEA), Taiwan","doi-asserted-by":"publisher","award":["Intramural Research Program of the National Instit"],"award-info":[{"award-number":["Intramural Research Program of the National Instit"]}],"id":[{"id":"10.13039\/501100002768","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["N Engl J Med"],"published-print":{"date-parts":[[2019,4,18]]},"DOI":"10.1056\/nejmoa1802264","type":"journal-article","created":{"date-parts":[[2019,4,17]],"date-time":"2019-04-17T17:01:21Z","timestamp":1555520481000},"page":"1535-1545","source":"Crossref","is-referenced-by-count":41,"title":["Effect of Anti-CD4 Antibody UB-421 on HIV-1 Rebound after Treatment Interruption"],"prefix":"10.1056","volume":"380","author":[{"given":"Chang-Yi","family":"Wang","sequence":"first","affiliation":[{"name":"From United Biomedical, Hauppauge, NY (C.-Y.W., B.-S.K., C.L.F., F.W.-S.); United Biomedical Asia (C.-Y.W., S.L.) and United BioPharma (C.-Y.W., B.-S.K., H.-W.S., C.-Y.L., F.-C.T., A.L., F.-H.Y., C.-H.L., W.T., M.-J.L.), Hsinchu, Taipei Veterans General Hospital, Taipei (W.-W.W., H.-Y.L.), and Kaohsiung Veterans General Hospital (H.-C.T.) and Kaohsiung Medical University Hospital (Y.-H.C.), Kaohsiung \u2014 all in Taiwan; National Institute of Allergy and Infectious Diseases, National Institutes of..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wing-Wai","family":"Wong","sequence":"additional","affiliation":[{"name":"From United Biomedical, Hauppauge, NY (C.-Y.W., B.-S.K., C.L.F., F.W.-S.); United Biomedical Asia (C.-Y.W., S.L.) and United BioPharma (C.-Y.W., B.-S.K., H.-W.S., C.-Y.L., F.-C.T., A.L., F.-H.Y., C.-H.L., W.T., M.-J.L.), Hsinchu, Taipei Veterans General Hospital, Taipei (W.-W.W., H.-Y.L.), and Kaohsiung Veterans General Hospital (H.-C.T.) and Kaohsiung Medical University Hospital (Y.-H.C.), Kaohsiung \u2014 all in Taiwan; National Institute of Allergy and Infectious Diseases, National Institutes of..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hung-Chin","family":"Tsai","sequence":"additional","affiliation":[{"name":"From United Biomedical, Hauppauge, NY (C.-Y.W., B.-S.K., C.L.F., F.W.-S.); United Biomedical Asia (C.-Y.W., S.L.) and United BioPharma (C.-Y.W., B.-S.K., H.-W.S., C.-Y.L., F.-C.T., A.L., F.-H.Y., C.-H.L., W.T., M.-J.L.), Hsinchu, Taipei Veterans General Hospital, Taipei (W.-W.W., H.-Y.L.), and Kaohsiung Veterans General Hospital (H.-C.T.) and Kaohsiung Medical University Hospital (Y.-H.C.), Kaohsiung \u2014 all in Taiwan; National Institute of Allergy and Infectious Diseases, National Institutes of..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yen-Hsu","family":"Chen","sequence":"additional","affiliation":[{"name":"From United Biomedical, Hauppauge, NY (C.-Y.W., B.-S.K., C.L.F., F.W.-S.); United Biomedical Asia (C.-Y.W., S.L.) and United BioPharma (C.-Y.W., B.-S.K., H.-W.S., C.-Y.L., F.-C.T., A.L., F.-H.Y., C.-H.L., W.T., M.-J.L.), Hsinchu, Taipei Veterans General Hospital, Taipei (W.-W.W., H.-Y.L.), and Kaohsiung Veterans General Hospital (H.-C.T.) and Kaohsiung Medical University Hospital (Y.-H.C.), Kaohsiung \u2014 all in Taiwan; National Institute of Allergy and Infectious Diseases, National Institutes of..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Be-Sheng","family":"Kuo","sequence":"additional","affiliation":[{"name":"From United Biomedical, Hauppauge, NY (C.-Y.W., B.-S.K., C.L.F., F.W.-S.); United Biomedical Asia (C.-Y.W., S.L.) and United BioPharma (C.-Y.W., B.-S.K., H.-W.S., C.-Y.L., F.-C.T., A.L., F.-H.Y., C.-H.L., W.T., M.-J.L.), Hsinchu, Taipei Veterans General Hospital, Taipei (W.-W.W., H.-Y.L.), and Kaohsiung Veterans General Hospital (H.-C.T.) and Kaohsiung Medical University Hospital (Y.-H.C.), Kaohsiung \u2014 all in Taiwan; National Institute of Allergy and Infectious Diseases, National Institutes of..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shugene","family":"Lynn","sequence":"additional","affiliation":[{"name":"From United Biomedical, Hauppauge, NY (C.-Y.W., B.-S.K., C.L.F., F.W.-S.); United Biomedical Asia (C.-Y.W., S.L.) and United BioPharma (C.-Y.W., B.-S.K., H.-W.S., C.-Y.L., F.-C.T., A.L., F.-H.Y., C.-H.L., W.T., M.-J.L.), Hsinchu, Taipei Veterans General Hospital, Taipei (W.-W.W., H.-Y.L.), and Kaohsiung Veterans General Hospital (H.-C.T.) and Kaohsiung Medical University Hospital (Y.-H.C.), Kaohsiung \u2014 all in Taiwan; National Institute of Allergy and Infectious Diseases, National Institutes of..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jana","family":"Blazkova","sequence":"additional","affiliation":[{"name":"From United Biomedical, Hauppauge, NY (C.-Y.W., B.-S.K., C.L.F., F.W.-S.); United Biomedical Asia (C.-Y.W., S.L.) and United BioPharma (C.-Y.W., B.-S.K., H.-W.S., C.-Y.L., F.-C.T., A.L., F.-H.Y., C.-H.L., W.T., M.-J.L.), Hsinchu, Taipei Veterans General Hospital, Taipei (W.-W.W., H.-Y.L.), and Kaohsiung Veterans General Hospital (H.-C.T.) and Kaohsiung Medical University Hospital (Y.-H.C.), Kaohsiung \u2014 all in Taiwan; National Institute of Allergy and Infectious Diseases, National Institutes of..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katherine E.","family":"Clarridge","sequence":"additional","affiliation":[{"name":"From United Biomedical, Hauppauge, NY (C.-Y.W., B.-S.K., C.L.F., F.W.-S.); United Biomedical Asia (C.-Y.W., S.L.) and United BioPharma (C.-Y.W., B.-S.K., H.-W.S., C.-Y.L., F.-C.T., A.L., F.-H.Y., C.-H.L., W.T., M.-J.L.), Hsinchu, Taipei Veterans General Hospital, Taipei (W.-W.W., H.-Y.L.), and Kaohsiung Veterans General Hospital (H.-C.T.) and Kaohsiung Medical University Hospital (Y.-H.C.), Kaohsiung \u2014 all in Taiwan; National Institute of Allergy and Infectious Diseases, National Institutes of..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hsiao-Wen","family":"Su","sequence":"additional","affiliation":[{"name":"From United Biomedical, Hauppauge, NY (C.-Y.W., B.-S.K., C.L.F., F.W.-S.); United Biomedical Asia (C.-Y.W., S.L.) and United BioPharma (C.-Y.W., B.-S.K., H.-W.S., C.-Y.L., F.-C.T., A.L., F.-H.Y., C.-H.L., W.T., M.-J.L.), Hsinchu, Taipei Veterans General Hospital, Taipei (W.-W.W., H.-Y.L.), and Kaohsiung Veterans General Hospital (H.-C.T.) and Kaohsiung Medical University Hospital (Y.-H.C.), Kaohsiung \u2014 all in Taiwan; National Institute of Allergy and Infectious Diseases, National Institutes of..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chia-Ying","family":"Lin","sequence":"additional","affiliation":[{"name":"From United Biomedical, Hauppauge, NY (C.-Y.W., B.-S.K., C.L.F., F.W.-S.); United Biomedical Asia (C.-Y.W., S.L.) and United BioPharma (C.-Y.W., B.-S.K., H.-W.S., C.-Y.L., F.-C.T., A.L., F.-H.Y., C.-H.L., W.T., M.-J.L.), Hsinchu, Taipei Veterans General Hospital, Taipei (W.-W.W., H.-Y.L.), and Kaohsiung Veterans General Hospital (H.-C.T.) and Kaohsiung Medical University Hospital (Y.-H.C.), Kaohsiung \u2014 all in Taiwan; National Institute of Allergy and Infectious Diseases, National Institutes of..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fan-Chen","family":"Tseng","sequence":"additional","affiliation":[{"name":"From United Biomedical, Hauppauge, NY (C.-Y.W., B.-S.K., C.L.F., F.W.-S.); United Biomedical Asia (C.-Y.W., S.L.) and United BioPharma (C.-Y.W., B.-S.K., H.-W.S., C.-Y.L., F.-C.T., A.L., F.-H.Y., C.-H.L., W.T., M.-J.L.), Hsinchu, Taipei Veterans General Hospital, Taipei (W.-W.W., H.-Y.L.), and Kaohsiung Veterans General Hospital (H.-C.T.) and Kaohsiung Medical University Hospital (Y.-H.C.), Kaohsiung \u2014 all in Taiwan; National Institute of Allergy and Infectious Diseases, National Institutes of..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Annie","family":"Lai","sequence":"additional","affiliation":[{"name":"From United Biomedical, Hauppauge, NY (C.-Y.W., B.-S.K., C.L.F., F.W.-S.); United Biomedical Asia (C.-Y.W., S.L.) and United BioPharma (C.-Y.W., B.-S.K., H.-W.S., C.-Y.L., F.-C.T., A.L., F.-H.Y., C.-H.L., W.T., M.-J.L.), Hsinchu, Taipei Veterans General Hospital, Taipei (W.-W.W., H.-Y.L.), and Kaohsiung Veterans General Hospital (H.-C.T.) and Kaohsiung Medical University Hospital (Y.-H.C.), Kaohsiung \u2014 all in Taiwan; National Institute of Allergy and Infectious Diseases, National Institutes of..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fu-Hung","family":"Yang","sequence":"additional","affiliation":[{"name":"From United Biomedical, Hauppauge, NY (C.-Y.W., B.-S.K., C.L.F., F.W.-S.); United Biomedical Asia (C.-Y.W., S.L.) and United BioPharma (C.-Y.W., B.-S.K., H.-W.S., C.-Y.L., F.-C.T., A.L., F.-H.Y., C.-H.L., W.T., M.-J.L.), Hsinchu, Taipei Veterans General Hospital, Taipei (W.-W.W., H.-Y.L.), and Kaohsiung Veterans General Hospital (H.-C.T.) and Kaohsiung Medical University Hospital (Y.-H.C.), Kaohsiung \u2014 all in Taiwan; National Institute of Allergy and Infectious Diseases, National Institutes of..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chen-Han","family":"Lin","sequence":"additional","affiliation":[{"name":"From United Biomedical, Hauppauge, NY (C.-Y.W., B.-S.K., C.L.F., F.W.-S.); United Biomedical Asia (C.-Y.W., S.L.) and United BioPharma (C.-Y.W., B.-S.K., H.-W.S., C.-Y.L., F.-C.T., A.L., F.-H.Y., C.-H.L., W.T., M.-J.L.), Hsinchu, Taipei Veterans General Hospital, Taipei (W.-W.W., H.-Y.L.), and Kaohsiung Veterans General Hospital (H.-C.T.) and Kaohsiung Medical University Hospital (Y.-H.C.), Kaohsiung \u2014 all in Taiwan; National Institute of Allergy and Infectious Diseases, National Institutes of..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William","family":"Tseng","sequence":"additional","affiliation":[{"name":"From United Biomedical, Hauppauge, NY (C.-Y.W., B.-S.K., C.L.F., F.W.-S.); United Biomedical Asia (C.-Y.W., S.L.) and United BioPharma (C.-Y.W., B.-S.K., H.-W.S., C.-Y.L., F.-C.T., A.L., F.-H.Y., C.-H.L., W.T., M.-J.L.), Hsinchu, Taipei Veterans General Hospital, Taipei (W.-W.W., H.-Y.L.), and Kaohsiung Veterans General Hospital (H.-C.T.) and Kaohsiung Medical University Hospital (Y.-H.C.), Kaohsiung \u2014 all in Taiwan; National Institute of Allergy and Infectious Diseases, National Institutes of..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hsiao-Yi","family":"Lin","sequence":"additional","affiliation":[{"name":"From United Biomedical, Hauppauge, NY (C.-Y.W., B.-S.K., C.L.F., F.W.-S.); United Biomedical Asia (C.-Y.W., S.L.) and United BioPharma (C.-Y.W., B.-S.K., H.-W.S., C.-Y.L., F.-C.T., A.L., F.-H.Y., C.-H.L., W.T., M.-J.L.), Hsinchu, Taipei Veterans General Hospital, Taipei (W.-W.W., H.-Y.L.), and Kaohsiung Veterans General Hospital (H.-C.T.) and Kaohsiung Medical University Hospital (Y.-H.C.), Kaohsiung \u2014 all in Taiwan; National Institute of Allergy and Infectious Diseases, National Institutes of..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Connie L.","family":"Finstad","sequence":"additional","affiliation":[{"name":"From United Biomedical, Hauppauge, NY (C.-Y.W., B.-S.K., C.L.F., F.W.-S.); United Biomedical Asia (C.-Y.W., S.L.) and United BioPharma (C.-Y.W., B.-S.K., H.-W.S., C.-Y.L., F.-C.T., A.L., F.-H.Y., C.-H.L., W.T., M.-J.L.), Hsinchu, Taipei Veterans General Hospital, Taipei (W.-W.W., H.-Y.L.), and Kaohsiung Veterans General Hospital (H.-C.T.) and Kaohsiung Medical University Hospital (Y.-H.C.), Kaohsiung \u2014 all in Taiwan; National Institute of Allergy and Infectious Diseases, National Institutes of..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Flossie","family":"Wong-Staal","sequence":"additional","affiliation":[{"name":"From United Biomedical, Hauppauge, NY (C.-Y.W., B.-S.K., C.L.F., F.W.-S.); United Biomedical Asia (C.-Y.W., S.L.) and United BioPharma (C.-Y.W., B.-S.K., H.-W.S., C.-Y.L., F.-C.T., A.L., F.-H.Y., C.-H.L., W.T., M.-J.L.), Hsinchu, Taipei Veterans General Hospital, Taipei (W.-W.W., H.-Y.L.), and Kaohsiung Veterans General Hospital (H.-C.T.) and Kaohsiung Medical University Hospital (Y.-H.C.), Kaohsiung \u2014 all in Taiwan; National Institute of Allergy and Infectious Diseases, National Institutes of..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carl V.","family":"Hanson","sequence":"additional","affiliation":[{"name":"From United Biomedical, Hauppauge, NY (C.-Y.W., B.-S.K., C.L.F., F.W.-S.); United Biomedical Asia (C.-Y.W., S.L.) and United BioPharma (C.-Y.W., B.-S.K., H.-W.S., C.-Y.L., F.-C.T., A.L., F.-H.Y., C.-H.L., W.T., M.-J.L.), Hsinchu, Taipei Veterans General Hospital, Taipei (W.-W.W., H.-Y.L.), and Kaohsiung Veterans General Hospital (H.-C.T.) and Kaohsiung Medical University Hospital (Y.-H.C.), Kaohsiung \u2014 all in Taiwan; National Institute of Allergy and Infectious Diseases, National Institutes of..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tae-Wook","family":"Chun","sequence":"additional","affiliation":[{"name":"From United Biomedical, Hauppauge, NY (C.-Y.W., B.-S.K., C.L.F., F.W.-S.); United Biomedical Asia (C.-Y.W., S.L.) and United BioPharma (C.-Y.W., B.-S.K., H.-W.S., C.-Y.L., F.-C.T., A.L., F.-H.Y., C.-H.L., W.T., M.-J.L.), Hsinchu, Taipei Veterans General Hospital, Taipei (W.-W.W., H.-Y.L.), and Kaohsiung Veterans General Hospital (H.-C.T.) and Kaohsiung Medical University Hospital (Y.-H.C.), Kaohsiung \u2014 all in Taiwan; National Institute of Allergy and Infectious Diseases, National Institutes of..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mei-June","family":"Liao","sequence":"additional","affiliation":[{"name":"From United Biomedical, Hauppauge, NY (C.-Y.W., B.-S.K., C.L.F., F.W.-S.); United Biomedical Asia (C.-Y.W., S.L.) and United BioPharma (C.-Y.W., B.-S.K., H.-W.S., C.-Y.L., F.-C.T., A.L., F.-H.Y., C.-H.L., W.T., M.-J.L.), Hsinchu, Taipei Veterans General Hospital, Taipei (W.-W.W., H.-Y.L.), and Kaohsiung Veterans General Hospital (H.-C.T.) and Kaohsiung Medical University Hospital (Y.-H.C.), Kaohsiung \u2014 all in Taiwan; National Institute of Allergy and Infectious Diseases, National Institutes of..."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"150","reference":[{"key":"e_1_3_4_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(13)61809-7"},{"key":"e_1_3_4_3_2","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.1600343"},{"key":"e_1_3_4_4_2","doi-asserted-by":"publisher","DOI":"10.1097\/QAD.0b013e328340a239"},{"key":"e_1_3_4_5_2","doi-asserted-by":"publisher","DOI":"10.1097\/QAD.0b013e328353f3f1"},{"key":"e_1_3_4_6_2","first-page":"132","article-title":"2017 Update of the drug resistance mutations in HIV-1.","volume":"24","author":"Wensing AM","year":"2017","unstructured":"Wensing AM, Calvez V, G\u00fcnthard HF, et al. 2017 Update of the drug resistance mutations in HIV-1. Top Antivir Med 2017;24:132-133.28208121","journal-title":"Top Antivir Med"},{"key":"e_1_3_4_7_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMc1611639"},{"key":"e_1_3_4_8_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12985-016-0628-x"},{"key":"e_1_3_4_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.coviro.2016.03.004"},{"key":"e_1_3_4_10_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1608243"},{"key":"e_1_3_4_11_2","doi-asserted-by":"publisher","DOI":"10.1038\/nature18929"},{"key":"e_1_3_4_12_2","doi-asserted-by":"publisher","DOI":"10.1038\/nm.4268"},{"key":"e_1_3_4_13_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.96.18.10367"},{"key":"e_1_3_4_14_2","unstructured":"Wang CY Wong WW Tsai HC et al. A phase 2 open-label trial of antibody UB-421 monotherapy as a substitute for HAART. Presented at the Conference on Retroviruses and Opportunistic Infections (CROI) 2017 Seattle February 13\u201316 2017:450LB-450LB. abstract."},{"key":"e_1_3_4_15_2","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v19.i31.5174"},{"key":"e_1_3_4_16_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0003305"},{"key":"e_1_3_4_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.smim.2012.02.006"},{"key":"e_1_3_4_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.virusres.2015.10.009"},{"key":"e_1_3_4_19_2","doi-asserted-by":"publisher","DOI":"10.1080\/15284336.2018.1452842"},{"key":"e_1_3_4_20_2","doi-asserted-by":"publisher","DOI":"10.1086\/652190"},{"key":"e_1_3_4_21_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.00942-08"},{"key":"e_1_3_4_22_2","unstructured":"Lin H-H Lee S-J Wang NC et al. Intramuscular ibalizumab: pharmacokinetics safety and efficacy vs intravenous administration. Presented at the Conference on Retroviruses and Opportunistic Infections (CROI) 2017 Seattle February 13\u201316 2017:438-438. abstract."},{"key":"e_1_3_4_23_2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.02237-10"},{"key":"e_1_3_4_24_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1711460"},{"key":"e_1_3_4_25_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2012-07-409755"},{"key":"e_1_3_4_26_2","doi-asserted-by":"publisher","DOI":"10.1097\/QAI.0000000000000919"}],"container-title":["New England Journal of Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.nejm.org\/doi\/pdf\/10.1056\/NEJMoa1802264","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,3,26]],"date-time":"2024-03-26T20:46:16Z","timestamp":1711485976000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.nejm.org\/doi\/10.1056\/NEJMoa1802264"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,4,18]]},"references-count":25,"journal-issue":{"issue":"16","published-print":{"date-parts":[[2019,4,18]]}},"alternative-id":["10.1056\/NEJMoa1802264"],"URL":"https:\/\/doi.org\/10.1056\/nejmoa1802264","relation":{"has-review":[{"id-type":"doi","id":"10.3410\/f.735565924.793559447","asserted-by":"object"}]},"ISSN":["0028-4793","1533-4406"],"issn-type":[{"value":"0028-4793","type":"print"},{"value":"1533-4406","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,4,18]]}}}