{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T20:53:12Z","timestamp":1790887992281,"version":"4.1.0"},"reference-count":20,"publisher":"Massachusetts Medical Society","issue":"25","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["N Engl J Med"],"published-print":{"date-parts":[[2020,6,18]]},"DOI":"10.1056\/nejmoa2008975","type":"journal-article","created":{"date-parts":[[2020,5,1]],"date-time":"2020-05-01T12:01:50Z","timestamp":1588334510000},"page":"2441-2448","source":"Crossref","is-referenced-by-count":908,"title":["Renin\u2013Angiotensin\u2013Aldosterone System Inhibitors and Risk of Covid-19"],"prefix":"10.1056","volume":"382","author":[{"given":"Harmony R.","family":"Reynolds","sequence":"first","affiliation":[{"name":"From the New York University (NYU) Grossman School of Medicine, New York."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samrachana","family":"Adhikari","sequence":"additional","affiliation":[{"name":"From the New York University (NYU) Grossman School of Medicine, New York."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claudia","family":"Pulgarin","sequence":"additional","affiliation":[{"name":"From the New York University (NYU) Grossman School of Medicine, New York."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea B.","family":"Troxel","sequence":"additional","affiliation":[{"name":"From the New York University (NYU) Grossman School of Medicine, New York."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eduardo","family":"Iturrate","sequence":"additional","affiliation":[{"name":"From the New York University (NYU) Grossman School of Medicine, New York."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephen B.","family":"Johnson","sequence":"additional","affiliation":[{"name":"From the New York University (NYU) Grossman School of Medicine, New York."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana\u00efs","family":"Hausvater","sequence":"additional","affiliation":[{"name":"From the New York University (NYU) Grossman School of Medicine, New York."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jonathan D.","family":"Newman","sequence":"additional","affiliation":[{"name":"From the New York University (NYU) Grossman School of Medicine, New York."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeffrey S.","family":"Berger","sequence":"additional","affiliation":[{"name":"From the New York University (NYU) Grossman School of Medicine, New York."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sripal","family":"Bangalore","sequence":"additional","affiliation":[{"name":"From the New York University (NYU) Grossman School of Medicine, New York."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stuart D.","family":"Katz","sequence":"additional","affiliation":[{"name":"From the New York University (NYU) Grossman School of Medicine, New York."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Glenn I.","family":"Fishman","sequence":"additional","affiliation":[{"name":"From the New York University (NYU) Grossman School of Medicine, New York."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dennis","family":"Kunichoff","sequence":"additional","affiliation":[{"name":"From the New York University (NYU) Grossman School of Medicine, New York."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu","family":"Chen","sequence":"additional","affiliation":[{"name":"From the New York University (NYU) Grossman School of Medicine, New York."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gbenga","family":"Ogedegbe","sequence":"additional","affiliation":[{"name":"From the New York University (NYU) Grossman School of Medicine, New York."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Judith S.","family":"Hochman","sequence":"additional","affiliation":[{"name":"From the New York University (NYU) Grossman School of Medicine, New York."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"150","reference":[{"key":"e_1_3_4_2_2","doi-asserted-by":"publisher","DOI":"10.1038\/nature02145"},{"key":"e_1_3_4_3_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMsr2005760"},{"key":"e_1_3_4_4_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.104.510461"},{"key":"e_1_3_4_5_2","first-page":"1280","article-title":"Angiotensin converting enzyme 2 activity and human atrial fibrillation: increased plasma angiotensin converting enzyme 2 activity is associated with atrial fibrillation and more advanced left atrial structural remodelling","volume":"19","author":"Walters TE","year":"2017","unstructured":"Walters TE, Kalman JM, Patel SK, Mearns M, Velkoska E, Burrell LM. Angiotensin converting enzyme 2 activity and human atrial fibrillation: increased plasma angiotensin converting enzyme 2 activity is associated with atrial fibrillation and more advanced left atrial structural remodelling. Europace 2017;19:1280-1287.27738071","journal-title":"Europace"},{"key":"e_1_3_4_6_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0198144"},{"key":"e_1_3_4_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0895-7061(99)00005-9"},{"key":"e_1_3_4_8_2","doi-asserted-by":"publisher","DOI":"10.1097\/FJC.0000000000000629"},{"key":"e_1_3_4_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/S2213-2600(20)30116-8"},{"key":"e_1_3_4_10_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2002032"},{"key":"e_1_3_4_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.abb.2008.09.019"},{"key":"e_1_3_4_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.chest.2016.02.161"},{"key":"e_1_3_4_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jss.2007.03.075"},{"key":"e_1_3_4_14_2","doi-asserted-by":"publisher","DOI":"10.1097\/SHK.0b013e3180310f3a"},{"key":"e_1_3_4_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.lfs.2016.10.010"},{"key":"e_1_3_4_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.pan.2016.05.395"},{"key":"e_1_3_4_17_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIR.0000000000000659"},{"key":"e_1_3_4_18_2","unstructured":"HFSA\/ACC\/AHA statement addresses concerns re: using RAAS antagonists in COVID-19. American College of Cardiology March 17 2020 (https:\/\/www.acc.org\/latest-in-cardiology\/articles\/2020\/03\/17\/08\/59\/hfsa-acc-aha-statement-addresses-concerns-re-using-raas-antagonists-in-covid-19)."},{"key":"e_1_3_4_19_2","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0258(19981015)17:19<2265::AID-SIM918>3.0.CO;2-B"},{"key":"e_1_3_4_20_2","doi-asserted-by":"crossref","unstructured":"Liu Y Huang F Xu J et al. Anti-hypertensive angiotensin II receptor blockers associated to mitigation of disease severity in elderly COVID-19 patients. March 27 2020 (https:\/\/www.medrxiv.org\/content\/10.1101\/2020.03.20.20039586v1.full.pdf) (preprint).","DOI":"10.1101\/2020.03.20.20039586"},{"key":"e_1_3_4_21_2","doi-asserted-by":"publisher","DOI":"10.1080\/22221751.2020.1746200"}],"container-title":["New England Journal of Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.nejm.org\/doi\/pdf\/10.1056\/NEJMoa2008975","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,3,26]],"date-time":"2024-03-26T20:46:02Z","timestamp":1711485962000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.nejm.org\/doi\/10.1056\/NEJMoa2008975"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,6,18]]},"references-count":20,"journal-issue":{"issue":"25","published-print":{"date-parts":[[2020,6,18]]}},"alternative-id":["10.1056\/NEJMoa2008975"],"URL":"https:\/\/doi.org\/10.1056\/nejmoa2008975","relation":{"has-review":[{"id-type":"doi","id":"10.3410\/f.737858036.793574341","asserted-by":"object"}]},"ISSN":["0028-4793","1533-4406"],"issn-type":[{"value":"0028-4793","type":"print"},{"value":"1533-4406","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,6,18]]}}}