{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,17]],"date-time":"2026-10-17T03:26:45Z","timestamp":1792207605760,"version":"4.4.0"},"reference-count":26,"publisher":"Massachusetts Medical Society","issue":"24","license":[{"start":{"date-parts":[[2021,12,9]],"date-time":"2021-12-09T00:00:00Z","timestamp":1639008000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/www.nejmgroup.org\/legal\/terms-of-use.htm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["N Engl J Med"],"published-print":{"date-parts":[[2021,12,9]]},"DOI":"10.1056\/nejmoa2109522","type":"journal-article","created":{"date-parts":[[2021,8,11]],"date-time":"2021-08-11T17:01:15Z","timestamp":1628701275000},"page":"2241-2251","source":"Crossref","is-referenced-by-count":338,"title":["Evaluation of mRNA-1273 SARS-CoV-2 Vaccine in Adolescents"],"prefix":"10.1056","volume":"385","author":[{"given":"Kashif","family":"Ali","sequence":"first","affiliation":[{"name":"From Kool Kids Pediatrics, DM Clinical Research, Houston (K.A.); the Clinical Research Institute, Minneapolis (G.B.); and Moderna, Cambridge, MA (H.Z., W.D., V.F., M.C.-V., B.D., J.D., B.G., W.H., R.P., J.M.M., B.L., R.M.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gary","family":"Berman","sequence":"additional","affiliation":[{"name":"From Kool Kids Pediatrics, DM Clinical Research, Houston (K.A.); the Clinical Research Institute, Minneapolis (G.B.); and Moderna, Cambridge, MA (H.Z., W.D., V.F., M.C.-V., B.D., J.D., B.G., W.H., R.P., J.M.M., B.L., R.M.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Honghong","family":"Zhou","sequence":"additional","affiliation":[{"name":"From Kool Kids Pediatrics, DM Clinical Research, Houston (K.A.); the Clinical Research Institute, Minneapolis (G.B.); and Moderna, Cambridge, MA (H.Z., W.D., V.F., M.C.-V., B.D., J.D., B.G., W.H., R.P., J.M.M., B.L., R.M.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weiping","family":"Deng","sequence":"additional","affiliation":[{"name":"From Kool Kids Pediatrics, DM Clinical Research, Houston (K.A.); the Clinical Research Institute, Minneapolis (G.B.); and Moderna, Cambridge, MA (H.Z., W.D., V.F., M.C.-V., B.D., J.D., B.G., W.H., R.P., J.M.M., B.L., R.M.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Veronica","family":"Faughnan","sequence":"additional","affiliation":[{"name":"From Kool Kids Pediatrics, DM Clinical Research, Houston (K.A.); the Clinical Research Institute, Minneapolis (G.B.); and Moderna, Cambridge, MA (H.Z., W.D., V.F., M.C.-V., B.D., J.D., B.G., W.H., R.P., J.M.M., B.L., R.M.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria","family":"Coronado-Voges","sequence":"additional","affiliation":[{"name":"From Kool Kids Pediatrics, DM Clinical Research, Houston (K.A.); the Clinical Research Institute, Minneapolis (G.B.); and Moderna, Cambridge, MA (H.Z., W.D., V.F., M.C.-V., B.D., J.D., B.G., W.H., R.P., J.M.M., B.L., R.M.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Baoyu","family":"Ding","sequence":"additional","affiliation":[{"name":"From Kool Kids Pediatrics, DM Clinical Research, Houston (K.A.); the Clinical Research Institute, Minneapolis (G.B.); and Moderna, Cambridge, MA (H.Z., W.D., V.F., M.C.-V., B.D., J.D., B.G., W.H., R.P., J.M.M., B.L., R.M.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jacqueline","family":"Dooley","sequence":"additional","affiliation":[{"name":"From Kool Kids Pediatrics, DM Clinical Research, Houston (K.A.); the Clinical Research Institute, Minneapolis (G.B.); and Moderna, Cambridge, MA (H.Z., W.D., V.F., M.C.-V., B.D., J.D., B.G., W.H., R.P., J.M.M., B.L., R.M.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bethany","family":"Girard","sequence":"additional","affiliation":[{"name":"From Kool Kids Pediatrics, DM Clinical Research, Houston (K.A.); the Clinical Research Institute, Minneapolis (G.B.); and Moderna, Cambridge, MA (H.Z., W.D., V.F., M.C.-V., B.D., J.D., B.G., W.H., R.P., J.M.M., B.L., R.M.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William","family":"Hillebrand","sequence":"additional","affiliation":[{"name":"From Kool Kids Pediatrics, DM Clinical Research, Houston (K.A.); the Clinical Research Institute, Minneapolis (G.B.); and Moderna, Cambridge, MA (H.Z., W.D., V.F., M.C.-V., B.D., J.D., B.G., W.H., R.P., J.M.M., B.L., R.M.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rolando","family":"Pajon","sequence":"additional","affiliation":[{"name":"From Kool Kids Pediatrics, DM Clinical Research, Houston (K.A.); the Clinical Research Institute, Minneapolis (G.B.); and Moderna, Cambridge, MA (H.Z., W.D., V.F., M.C.-V., B.D., J.D., B.G., W.H., R.P., J.M.M., B.L., R.M.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jacqueline M.","family":"Miller","sequence":"additional","affiliation":[{"name":"From Kool Kids Pediatrics, DM Clinical Research, Houston (K.A.); the Clinical Research Institute, Minneapolis (G.B.); and Moderna, Cambridge, MA (H.Z., W.D., V.F., M.C.-V., B.D., J.D., B.G., W.H., R.P., J.M.M., B.L., R.M.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brett","family":"Leav","sequence":"additional","affiliation":[{"name":"From Kool Kids Pediatrics, DM Clinical Research, Houston (K.A.); the Clinical Research Institute, Minneapolis (G.B.); and Moderna, Cambridge, MA (H.Z., W.D., V.F., M.C.-V., B.D., J.D., B.G., W.H., R.P., J.M.M., B.L., R.M.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roderick","family":"McPhee","sequence":"additional","affiliation":[{"name":"From Kool Kids Pediatrics, DM Clinical Research, Houston (K.A.); the Clinical Research Institute, Minneapolis (G.B.); and Moderna, Cambridge, MA (H.Z., W.D., V.F., M.C.-V., B.D., J.D., B.G., W.H., R.P., J.M.M., B.L., R.M.)."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"150","reference":[{"key":"e_1_3_5_2_2","unstructured":"World Health Organization. WHO Coronavirus Disease (COVID-19) Dashboard June 7 2021 (https:\/\/covid19.who.int\/)."},{"key":"e_1_3_5_3_2","unstructured":"Wallace M Oliver S. COVID-19 mRNA vaccines in adolescents and young adults: benefit-risk discussion. Atlanta: Centers for Disease Control and Prevention. June 23 2021 (https:\/\/www.cdc.gov\/vaccines\/acip\/meetings\/downloads\/slides-2021-06\/05-COVID-Wallace-508.pdf)."},{"key":"e_1_3_5_4_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41591-020-0962-9"},{"key":"e_1_3_5_5_2","doi-asserted-by":"publisher","DOI":"10.15585\/mmwr.mm7023e1"},{"key":"e_1_3_5_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/S2352-4642(21)00138-3"},{"key":"e_1_3_5_7_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.abe8372"},{"key":"e_1_3_5_8_2","doi-asserted-by":"publisher","DOI":"10.15585\/mmwr.mm6949a1"},{"key":"e_1_3_5_9_2","doi-asserted-by":"publisher","DOI":"10.1111\/inm.12735"},{"key":"e_1_3_5_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpubeco.2020.104258"},{"key":"e_1_3_5_11_2","unstructured":"European Centre for Disease Prevention and Control. SARS-CoV-2 transmission and children 2021 (https:\/\/www.ecdc.europa.eu\/en\/covid-19\/latest-evidence\/transmission)."},{"key":"e_1_3_5_12_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2028436"},{"key":"e_1_3_5_13_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2022483"},{"key":"e_1_3_5_14_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMc2103916"},{"key":"e_1_3_5_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2021.02.007"},{"key":"e_1_3_5_16_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2035389"},{"key":"e_1_3_5_17_2","unstructured":"Food and Drug Administration. Moderna COVID-19 vaccine. June 7 2021 (https:\/\/www.fda.gov\/emergency-preparedness-and-response\/coronavirus-disease-2019-covid-19\/moderna-covid-19-vaccine)."},{"key":"e_1_3_5_18_2","unstructured":"Centers for Disease Control and Prevention. Symptoms of COVID-19 2021 (https:\/\/www.cdc.gov\/coronavirus\/2019-ncov\/symptoms-testing\/symptoms.html)."},{"key":"e_1_3_5_19_2","doi-asserted-by":"publisher","DOI":"10.1001\/jamanetworkopen.2021.8824"},{"key":"e_1_3_5_20_2","doi-asserted-by":"publisher","DOI":"10.15585\/mmwr.mm6950e3"},{"key":"e_1_3_5_21_2","doi-asserted-by":"publisher","DOI":"10.1001\/jamapediatrics.2020.4573"},{"key":"e_1_3_5_22_2","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2020-048090"},{"key":"e_1_3_5_23_2","doi-asserted-by":"publisher","DOI":"10.15585\/mmwr.mm6932e3"},{"key":"e_1_3_5_24_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2107456"},{"key":"e_1_3_5_25_2","doi-asserted-by":"crossref","unstructured":"Food and Drug Administration. Coronavirus (COVID-19) update: FDA authorizes Pfizer-BioNTech COVID-19 vaccine for emergency use in adolescents in another important action in fight against pandemic. May 10 2021 (https:\/\/www.fda.gov\/news-events\/press-announcements\/coronavirus-covid-19-update-fda-authorizes-pfizer-biontech-covid-19-vaccine-emergency-use).","DOI":"10.47287\/cen-09931-buscon1"},{"key":"e_1_3_5_26_2","unstructured":"Shimabukuro T. COVID-19 vaccine safety updates. Atlanta: Centers for Disease Control and Prevention. June 23 2021 (https:\/\/www.cdc.gov\/vaccines\/acip\/meetings\/downloads\/slides-2021-06\/03-COVID-Shimabukuro-508.pdf)."},{"key":"e_1_3_5_27_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2027906"}],"container-title":["New England Journal of Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.nejm.org\/doi\/pdf\/10.1056\/NEJMoa2109522","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,6,11]],"date-time":"2025-06-11T19:23:50Z","timestamp":1749669830000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.nejm.org\/doi\/10.1056\/NEJMoa2109522"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,12,9]]},"references-count":26,"journal-issue":{"issue":"24","published-print":{"date-parts":[[2021,12,9]]}},"alternative-id":["10.1056\/NEJMoa2109522"],"URL":"https:\/\/doi.org\/10.1056\/nejmoa2109522","relation":{"has-review":[{"id-type":"doi","id":"10.3410\/f.740628329.793588745","asserted-by":"object"},{"id-type":"doi","id":"10.32388\/5ZAJ0U","asserted-by":"object"}]},"ISSN":["0028-4793","1533-4406"],"issn-type":[{"value":"0028-4793","type":"print"},{"value":"1533-4406","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,12,9]]}}}