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the Department of Pediatrics, Children\u2019s Hospital of Eastern Ontario and University of Ottawa (P.C., S.S., D.W., C.L., D.E.D., J.L.), the Department of Obstetrics and Gynecology, Division of Maternal\u2013Fetal Medicine, Ottawa Hospital, University of Ottawa (K.F.-K.-F., F.M.), and Children\u2019s Hospital of Eastern Ontario Research Institute (P.C., A.D.) \u2014 all in Ottawa; the University of California, San Francisco (UCSF) Benioff Children\u2019s Hospital and the UCSF Center for Maternal\u2013Fetal Precision Medicine, San Francisco (M.E.S., A.M.-G., B.R.L., P.H., T.C.M.); and the Department of Chemistry, University of Washington, Seattle (M.H.G., H.K.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pranesh","family":"Chakraborty","sequence":"additional","affiliation":[{"name":"From the Department of Pediatrics, Division of Medical Genetics (J.L.C., D.B., S.P.Y., P.S.K.), and the Department of Pathology (K.C.S.), Duke University, Durham, NC; the Department of Pediatrics, Children\u2019s Hospital of Eastern Ontario and University of Ottawa (P.C., S.S., D.W., C.L., D.E.D., J.L.), the Department of Obstetrics and Gynecology, Division of Maternal\u2013Fetal Medicine, Ottawa Hospital, University of Ottawa (K.F.-K.-F., F.M.), and Children\u2019s Hospital of Eastern Ontario Research Institute (P.C., A.D.) \u2014 all in Ottawa; the University of California, San Francisco (UCSF) Benioff Children\u2019s Hospital and the UCSF Center for Maternal\u2013Fetal Precision Medicine, San Francisco (M.E.S., A.M.-G., B.R.L., P.H., T.C.M.); and the Department of Chemistry, University of Washington, Seattle (M.H.G., H.K.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karen","family":"Fung-Kee-Fung","sequence":"additional","affiliation":[{"name":"From the Department of Pediatrics, Division of Medical Genetics (J.L.C., D.B., S.P.Y., P.S.K.), and the Department of Pathology (K.C.S.), Duke University, Durham, NC; the Department of Pediatrics, Children\u2019s Hospital of Eastern Ontario and University of Ottawa (P.C., S.S., D.W., C.L., D.E.D., J.L.), the Department of Obstetrics and Gynecology, Division of Maternal\u2013Fetal Medicine, Ottawa Hospital, University of Ottawa (K.F.-K.-F., F.M.), and Children\u2019s Hospital of Eastern Ontario Research Institute (P.C., A.D.) \u2014 all in Ottawa; the University of California, San Francisco (UCSF) Benioff Children\u2019s Hospital and the UCSF Center for Maternal\u2013Fetal Precision Medicine, San Francisco (M.E.S., A.M.-G., B.R.L., P.H., T.C.M.); 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the University of California, San Francisco (UCSF) Benioff Children\u2019s Hospital and the UCSF Center for Maternal\u2013Fetal Precision Medicine, San Francisco (M.E.S., A.M.-G., B.R.L., P.H., T.C.M.); and the Department of Chemistry, University of Washington, Seattle (M.H.G., H.K.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hamid","family":"Khaledi","sequence":"additional","affiliation":[{"name":"From the Department of Pediatrics, Division of Medical Genetics (J.L.C., D.B., S.P.Y., P.S.K.), and the Department of Pathology (K.C.S.), Duke University, Durham, NC; the Department of Pediatrics, Children\u2019s Hospital of Eastern Ontario and University of Ottawa (P.C., S.S., D.W., C.L., D.E.D., J.L.), the Department of Obstetrics and Gynecology, Division of Maternal\u2013Fetal Medicine, Ottawa Hospital, University of Ottawa (K.F.-K.-F., F.M.), and Children\u2019s Hospital of Eastern Ontario Research Institute (P.C., A.D.) \u2014 all in Ottawa; the University of California, San Francisco (UCSF) Benioff Children\u2019s Hospital and the UCSF Center for Maternal\u2013Fetal Precision Medicine, San Francisco (M.E.S., A.M.-G., B.R.L., P.H., T.C.M.); 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