{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,30]],"date-time":"2026-10-30T23:57:56Z","timestamp":1793404676243,"version":"4.5.0"},"reference-count":21,"publisher":"Massachusetts Medical Society","issue":"8","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["N Engl J Med"],"published-print":{"date-parts":[[2022,8,25]]},"DOI":"10.1056\/nejmoa2207323","type":"journal-article","created":{"date-parts":[[2022,7,21]],"date-time":"2022-07-21T17:00:11Z","timestamp":1658422811000},"page":"679-691","source":"Crossref","is-referenced-by-count":1961,"title":["Monkeypox Virus Infection in Humans across 16 Countries \u2014 April\u2013June 2022"],"prefix":"10.1056","volume":"387","author":[{"given":"John P.","family":"Thornhill","sequence":"first","affiliation":[{"name":"From the Blizard Institute and the SHARE Collaborative, Queen Mary University of London, and the Department of Infection and Immunity, Barts Health NHS Trust (J.P.T., V.A., C.M.O.), the Department of Genitourinary Medicine and Infectious Disease, Guys and St. Thomas\u2019 NHS Trust (A.N.), the Department of Sexual Health, Homerton University Hospital (I.R.), and the Clinical Infection Unit, St. George\u2019s University Hospitals NHS Foundation Trust (M.S.H.) \u2014 all in London; the Department of Medicine, Division of Infectious Diseases (S.B., L.B.H., M.B.K.), the J.D. MacLean Centre for Tropical Diseases (S.B.), the Research Institute of the McGill University Health Centre (S.B., M.B.K.), and the Chronic Viral Illness Service, Department of Medicine (M.B.K.), McGill University Health Centre, Montreal, and the Department of Medicine, University Health Network, University of Toronto (S.W.), the Division of Infectious Diseases and the MAP Centre for Urban Health Solutions, St. Michael\u2019s Hospital (D.T.), and the Departmen..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sapha","family":"Barkati","sequence":"additional","affiliation":[{"name":"From the Blizard Institute and the SHARE Collaborative, Queen Mary University of London, and the Department of Infection and Immunity, Barts Health NHS Trust (J.P.T., V.A., C.M.O.), the Department of Genitourinary Medicine and Infectious Disease, Guys and St. Thomas\u2019 NHS Trust (A.N.), the Department of Sexual Health, Homerton University Hospital (I.R.), and the Clinical Infection Unit, St. George\u2019s University Hospitals NHS Foundation Trust (M.S.H.) \u2014 all in London; the Department of Medicine, Division of Infectious Diseases (S.B., L.B.H., M.B.K.), the J.D. MacLean Centre for Tropical Diseases (S.B.), the Research Institute of the McGill University Health Centre (S.B., M.B.K.), and the Chronic Viral Illness Service, Department of Medicine (M.B.K.), McGill University Health Centre, Montreal, and the Department of Medicine, University Health Network, University of Toronto (S.W.), the Division of Infectious Diseases and the MAP Centre for Urban Health Solutions, St. Michael\u2019s Hospital (D.T.), and the Departmen..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sharon","family":"Walmsley","sequence":"additional","affiliation":[{"name":"From the Blizard Institute and the SHARE Collaborative, Queen Mary University of London, and the Department of Infection and Immunity, Barts Health NHS Trust (J.P.T., V.A., C.M.O.), the Department of Genitourinary Medicine and Infectious Disease, Guys and St. Thomas\u2019 NHS Trust (A.N.), the Department of Sexual Health, Homerton University Hospital (I.R.), and the Clinical Infection Unit, St. George\u2019s University Hospitals NHS Foundation Trust (M.S.H.) \u2014 all in London; the Department of Medicine, Division of Infectious Diseases (S.B., L.B.H., M.B.K.), the J.D. MacLean Centre for Tropical Diseases (S.B.), the Research Institute of the McGill University Health Centre (S.B., M.B.K.), and the Chronic Viral Illness Service, Department of Medicine (M.B.K.), McGill University Health Centre, Montreal, and the Department of Medicine, University Health Network, University of Toronto (S.W.), the Division of Infectious Diseases and the MAP Centre for Urban Health Solutions, St. Michael\u2019s Hospital (D.T.), and the Departmen..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juergen","family":"Rockstroh","sequence":"additional","affiliation":[{"name":"From the Blizard Institute and the SHARE Collaborative, Queen Mary University of London, and the Department of Infection and Immunity, Barts Health NHS Trust (J.P.T., V.A., C.M.O.), the Department of Genitourinary Medicine and Infectious Disease, Guys and St. Thomas\u2019 NHS Trust (A.N.), the Department of Sexual Health, Homerton University Hospital (I.R.), and the Clinical Infection Unit, St. George\u2019s University Hospitals NHS Foundation Trust (M.S.H.) \u2014 all in London; the Department of Medicine, Division of Infectious Diseases (S.B., L.B.H., M.B.K.), the J.D. MacLean Centre for Tropical Diseases (S.B.), the Research Institute of the McGill University Health Centre (S.B., M.B.K.), and the Chronic Viral Illness Service, Department of Medicine (M.B.K.), McGill University Health Centre, Montreal, and the Department of Medicine, University Health Network, University of Toronto (S.W.), the Division of Infectious Diseases and the MAP Centre for Urban Health Solutions, St. Michael\u2019s Hospital (D.T.), and the Departmen..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"Antinori","sequence":"additional","affiliation":[{"name":"From the Blizard Institute and the SHARE Collaborative, Queen Mary University of London, and the Department of Infection and Immunity, Barts Health NHS Trust (J.P.T., V.A., C.M.O.), the Department of Genitourinary Medicine and Infectious Disease, Guys and St. Thomas\u2019 NHS Trust (A.N.), the Department of Sexual Health, Homerton University Hospital (I.R.), and the Clinical Infection Unit, St. George\u2019s University Hospitals NHS Foundation Trust (M.S.H.) \u2014 all in London; the Department of Medicine, Division of Infectious Diseases (S.B., L.B.H., M.B.K.), the J.D. MacLean Centre for Tropical Diseases (S.B.), the Research Institute of the McGill University Health Centre (S.B., M.B.K.), and the Chronic Viral Illness Service, Department of Medicine (M.B.K.), McGill University Health Centre, Montreal, and the Department of Medicine, University Health Network, University of Toronto (S.W.), the Division of Infectious Diseases and the MAP Centre for Urban Health Solutions, St. Michael\u2019s Hospital (D.T.), and the Departmen..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luke B.","family":"Harrison","sequence":"additional","affiliation":[{"name":"From the Blizard Institute and the SHARE Collaborative, Queen Mary University of London, and the Department of Infection and Immunity, Barts Health NHS Trust (J.P.T., V.A., C.M.O.), the Department of Genitourinary Medicine and Infectious Disease, Guys and St. Thomas\u2019 NHS Trust (A.N.), the Department of Sexual Health, Homerton University Hospital (I.R.), and the Clinical Infection Unit, St. George\u2019s University Hospitals NHS Foundation Trust (M.S.H.) \u2014 all in London; the Department of Medicine, Division of Infectious Diseases (S.B., L.B.H., M.B.K.), the J.D. MacLean Centre for Tropical Diseases (S.B.), the Research Institute of the McGill University Health Centre (S.B., M.B.K.), and the Chronic Viral Illness Service, Department of Medicine (M.B.K.), McGill University Health Centre, Montreal, and the Department of Medicine, University Health Network, University of Toronto (S.W.), the Division of Infectious Diseases and the MAP Centre for Urban Health Solutions, St. Michael\u2019s Hospital (D.T.), and the Departmen..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0047-0101","authenticated-orcid":false,"given":"Romain","family":"Palich","sequence":"additional","affiliation":[{"name":"From the Blizard Institute and the SHARE Collaborative, Queen Mary University of London, and the Department of Infection and Immunity, Barts Health NHS Trust (J.P.T., V.A., C.M.O.), the Department of Genitourinary Medicine and Infectious Disease, Guys and St. Thomas\u2019 NHS Trust (A.N.), the Department of Sexual Health, Homerton University Hospital (I.R.), and the Clinical Infection Unit, St. George\u2019s University Hospitals NHS Foundation Trust (M.S.H.) \u2014 all in London; the Department of Medicine, Division of Infectious Diseases (S.B., L.B.H., M.B.K.), the J.D. 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