{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T12:03:25Z","timestamp":1792670605495,"version":"4.5.0"},"reference-count":37,"publisher":"Massachusetts Medical Society","issue":"8","license":[{"start":{"date-parts":[[2025,8,21]],"date-time":"2025-08-21T00:00:00Z","timestamp":1755734400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/www.nejmgroup.org\/legal\/terms-of-use.htm"}],"funder":[{"DOI":"10.13039\/100004326","name":"Bayer","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004326","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["N Engl J Med"],"published-print":{"date-parts":[[2025,8,21]]},"DOI":"10.1056\/nejmoa2415566","type":"journal-article","created":{"date-parts":[[2025,6,2]],"date-time":"2025-06-02T08:02:06Z","timestamp":1748851326000},"page":"753-763","source":"Crossref","is-referenced-by-count":67,"title":["Elinzanetant for Vasomotor Symptoms from Endocrine Therapy for Breast Cancer"],"prefix":"10.1056","volume":"393","author":[{"given":"Fatima","family":"Cardoso","sequence":"first","affiliation":[{"name":"Breast Unit, Champalimaud Clinical Center, Champalimaud Foundation, Lisbon, Portugal"},{"name":"ABC Global Alliance, Lisbon, Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susanne","family":"Parke","sequence":"additional","affiliation":[{"name":"Bayer, Berlin"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Donal J.","family":"Brennan","sequence":"additional","affiliation":[{"name":"University College Dublin Gynaecological Oncology Group, UCD School of Medicine, Mater Misericordiae University Hospital, Dublin"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paula","family":"Briggs","sequence":"additional","affiliation":[{"name":"Liverpool Women\u2019s Hospital, Liverpool, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gilbert","family":"Donders","sequence":"additional","affiliation":[{"name":"Department of Clinical Research for Women, Femicare, Tienen, Belgium"},{"name":"Department of Obstetrics and Gynecology, University Hospital, University of Antwerp, Antwerp, Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nick","family":"Panay","sequence":"additional","affiliation":[{"name":"Queen Charlotte\u2019s and Chelsea Hospital, Imperial College London, London"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nazanin","family":"Haseli-Mashhadi","sequence":"additional","affiliation":[{"name":"Bayer, Reading, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Block","sequence":"additional","affiliation":[{"name":"Bayer, Leverkusen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cecilia","family":"Caetano","sequence":"additional","affiliation":[{"name":"Bayer, Basel, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maja","family":"Francuski","sequence":"additional","affiliation":[{"name":"Bayer, Berlin"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claudia","family":"Haberland","sequence":"additional","affiliation":[{"name":"Bayer, Berlin"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kaisa","family":"Laapas","sequence":"additional","affiliation":[{"name":"Bayer, Espoo, Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian","family":"Seitz","sequence":"additional","affiliation":[{"name":"Bayer, Berlin"},{"name":"Charit\u00e9\u2013Universit\u00e4tsmedizin Berlin, Berlin"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lineke","family":"Zuurman","sequence":"additional","affiliation":[{"name":"Bayer, Basel, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"150","reference":[{"key":"e_1_3_5_2_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-024-74746-1"},{"key":"e_1_3_5_3_2","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.21.01392"},{"key":"e_1_3_5_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.annonc.2022.07.007"},{"key":"e_1_3_5_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.annonc.2023.11.016"},{"key":"e_1_3_5_6_2","unstructured":"National Comprehensive Cancer Network. Clinical practice guidelines in oncology: breast cancer. Version 6. 2024 (https:\/\/www.nccn.org\/professionals\/physician_gls\/pdf\/breast.pdf)."},{"key":"e_1_3_5_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(11)60993-8"},{"key":"e_1_3_5_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(12)61963-1"},{"key":"e_1_3_5_9_2","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.63333"},{"key":"e_1_3_5_10_2","unstructured":"Electronic Medicines Compendium. Arimidex 1mg film-coated tablet. July 2024 (https:\/\/www.medicines.org.uk\/emc\/product\/2199\/smpc)."},{"key":"e_1_3_5_11_2","doi-asserted-by":"publisher","DOI":"10.1007\/s11764-020-00908-5"},{"key":"e_1_3_5_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0378-5122(03)00087-2"},{"key":"e_1_3_5_13_2","unstructured":"Electronic Medicines Compendium. Tamoxifen 20mg film-coated tablets August 2021 (https:\/\/www.medicines.org.uk\/emc\/product\/2248\/smpc)."},{"key":"e_1_3_5_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(23)02802-7"},{"key":"e_1_3_5_15_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10549-007-9548-1"},{"key":"e_1_3_5_16_2","doi-asserted-by":"publisher","DOI":"10.1634\/theoncologist.11-2-96"},{"key":"e_1_3_5_17_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10549-012-2114-5"},{"key":"e_1_3_5_18_2","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21319"},{"key":"e_1_3_5_19_2","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.19.01758"},{"key":"e_1_3_5_20_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.yfrne.2013.07.003"},{"key":"e_1_3_5_21_2","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.1569-09.2009"},{"key":"e_1_3_5_22_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.peptides.2008.05.016"},{"key":"e_1_3_5_23_2","doi-asserted-by":"publisher","DOI":"10.1210\/en.2014-1651"},{"key":"e_1_3_5_24_2","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.2006.112508"},{"key":"e_1_3_5_25_2","doi-asserted-by":"publisher","DOI":"10.5665\/sleep.3208"},{"key":"e_1_3_5_26_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2024.14618"},{"key":"e_1_3_5_27_2","unstructured":"Panay N Joffe H Maki P et al. Efficacy and long-term safety of elinzanetant for the treatment of VMS associated with menopause: a phase 3 randomized trial (OASIS 3). In: Proceedings and abstracts of the 2024 Annual Meeting of the Menopause Society September 11\u201314 2024. Chicago: Menopause Society 2024."},{"key":"e_1_3_5_28_2","doi-asserted-by":"publisher","DOI":"10.1097\/GME.0000000000002354"},{"key":"e_1_3_5_29_2","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2015.64.3866"},{"key":"e_1_3_5_30_2","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2009.25.9655"},{"key":"e_1_3_5_31_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.breast.2022.01.012"},{"key":"e_1_3_5_32_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(05)70316-8"},{"key":"e_1_3_5_33_2","doi-asserted-by":"publisher","DOI":"10.1097\/GME.0000000000002028"},{"key":"e_1_3_5_34_2","doi-asserted-by":"publisher","DOI":"10.1097\/GME.0000000000002200"},{"key":"e_1_3_5_35_2","doi-asserted-by":"publisher","DOI":"10.1007\/s11764-021-01114-7"},{"key":"e_1_3_5_36_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(11)70364-3"},{"key":"e_1_3_5_37_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(20)30666-5"},{"key":"e_1_3_5_38_2","doi-asserted-by":"publisher","DOI":"10.3332\/ecancer.2019.909"}],"container-title":["New England Journal of Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.nejm.org\/doi\/pdf\/10.1056\/NEJMoa2415566","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T14:03:00Z","timestamp":1761573780000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.nejm.org\/doi\/10.1056\/NEJMoa2415566"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,8,21]]},"references-count":37,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2025,8,21]]}},"alternative-id":["10.1056\/NEJMoa2415566"],"URL":"https:\/\/doi.org\/10.1056\/nejmoa2415566","relation":{},"ISSN":["0028-4793","1533-4406"],"issn-type":[{"value":"0028-4793","type":"print"},{"value":"1533-4406","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,8,21]]}}}